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Medication is available with a prescription under the brand names Ultram and Ultram ER. Other brand or generic formulations may also be available.

Do not crush the pill tablet. This medicine is for oral (by mouth) use only. Powder from a crushed tablet should not be inhaled or diluted with liquid and injected into the body.

Ask your pharmacist any questions you have about this medication, especially if it is new to you. Using this medicine by inhlation or injection can cause life-threatening side effects, overdose, or death.

Do not stop taking medication suddenly without talking to your doctor. If you suddenly stop taking medication, you may experience side effects. Your doctor will probably decrease your dose gradually.

While you are taking pill, do not drink alcohol or use drugs that make you sleepy (such as cold medicine, other pain medications, muscle relaxants, and medicine for seizures, depression or anxiety). These drugs may slow your breathing or increase drowsiness when used together with pill.

Then tell your doctor and pharmacist what other prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking. If you experience a serious side effect, you or your doctor may send a report to the administration.