Hello Group,

I am currently on the editorial staff of four peer-reviewed
dermatological journals.  I review mostly rosacea articles and acne
articles.  Anyway, I have been inundated with 9 new manuscripts on
the role of demodex in rosacea.  7 out of the 9 manuscripts are very
well done.

I believe that most people know my feelings on the role that demodex
play in rosacea -- minimal to none.  However, as a medical scientist
I must continue to keep my eye open and perform research without
bias.  I am realizing that in a significant portion of rosacea
sufferers (possibly 30% to 40%) that demodex may play a secondary
role in rosacea symptoms. They are NOT the underlying cause of
rosacea, but they can cause papules, pustules, itchiness, extreme
skin hypersensitivity, cosmetic intolerance syndrome, folliculitis,
burning, chronic facial redness and increase the intensity/duration
of flushing.

What has changed my mind?  The above mentioned studies.  Oral
treatment with an anti-mite drug has resulted in substantial
improvement in all the above symptoms in approximately 40% of the
cases (several hundred cases within the 9 articles).  They are not
using topical sulfur, Eurax or permetherin because it takes a long
time to kill the mites topically and the inactive ingredient bases
are usually quite irritating and very drying.

Oral Ivermectin (Stromectol) is making a huge difference in these
sufferers facial symptoms and flushing triggers (yes, I said
flushing triggers).  Ivermectin is an anti-mite drug that is related
to the macrolide antibiotics.  It has a very good safety profile and
less side effects than most antibiotics (and not one major side
effect).  In addition, the treatment regimen is so simple and it can
be used for treatment and diagnoses:

Treatment Regimen:

For patients under 100 pounds -- 6 mgs per day with food.  For
patients over 100 pounds -- 12 mgs per day with food.

Treatment of Mild Demodex Infestation:  One single treatment every 6
months

Treatment of Moderate Demodex Infestation:  One treatment every week
for 4 weeks.  This is followed by one single treatment every 6
months.

Treatment of Severe Demodex Infestation:  One treatment every day
for two weeks.  This is followed by one single treatment every 6
months.


It is quite inexpensive and may be worth a try for those who are not
responding to other treatments or have angry face sydrome or severe
skin hypersensitivity. You know who you are.


Regards,

Geoffrey
______________________________

Dr. Geoffrey Nase
Ph.D. Microvascular Physiologist
http://www.drnase.com
______________________________

I personally used the loose.  It's so funny you asked this today...I was just
talking to an
esthetician that specializes in JI about which is better for oily skin.  She
said it was a matter of
preference.  You see, the loose has a bit of a shimmer to it, so some people
don't like it.  That's
the only difference between the loose and the pressed.  I am on the younger side
of the age
spectrum, so I like the trendy shimmery effect.  I also hear people with dull
skin likes it because
it gives the skin a bit of luminosity.  So it really is just a matter of
preference.

I hope this helps.  Please feel free to ask me any sort of makeup/cover up
questions.  I'm not a PhD
like some of the great folks on this list (and my hat's off to each and every
one of you; I went the
law route instead of the med school route), but I have worn makeup for over half
of my life, so if
it's out there I've probably tried it all at one point or another.

Sincerely,
Melanie

*-----Original Message-----
*From: Ly, An [mailto:An.Ly@...]
*Sent: Wednesday, October 20, 2004 5:50 AM
*To: Atlanta Bastet
*Subject: RE: [rosacea] Ladies w/oily skin - what foundation do you use?
*
*Do you use the purepressed minerals or the amazing loose powder?
*
*Thanks
*
*-----Original Message-----
*From: Atlanta Bastet [mailto:atlanta.bastet@...]
*Sent: 20 September 2004 18:42
*To: rosacea-support@yahoogroups.com
*Subject: RE: [rosacea] Ladies w/oily skin - what foundation do you use?
*
*
*I personally use Jane Iredale's mineral makeup
*(http://www.janeiredale.com/index.html).  It works great as
*long as you have exfoliated the flakes off.  Otherwise, like
*most foundations, you look scaly.  If you don't have a flake
*problem, though, it is fantastic and doubles as a strong,
*waterproof sunscreen as well.  It kept my lilly white
*sensitive skin safe in Cancun in May.  I was so impressed.
*And it is easy to wash off.  I just use my regular cleanser.
*
*Sincerely,
*Melanie
*New List Member

I don't know if any of you live in or near Birmingham Alabama, but I
heard on the radio that they were doing a study on rosacea and were
trying new stuff. I cannot participate because of other health issue.
But if any of your interested the number is 205-933-2292. I hope all
are having a redless day.


Kathy

I am considering giving the products a try, I would like to hear from anyone who
is currently or has used these products.

An

*******************************************************************
CONFIDENTIALITY NOTICE/DISCLAIMER
This email and any attachments are confidential, protected by
copyright/intellectual property rights and may be legally privileged. The
information transmitted is intended only for the person or entity to which it is
addressed.  If you are not the intended recipient, dissemination or copying of
this email is prohibited.
If you have received this in error, please notify us by forwarding this email to
the following address: info@... , and then delete the email
completely from your system.
This email and any attachments have been scanned for computer viruses by a
market leading anti-virus system. However, it is the responsibility of the
recipient to conduct its own security measures. No responsibility is accepted by
ROOM Solutions Limited for loss or damage arising from the receipt or use of
this email and any attachments.
No responsibility is accepted by ROOM Solutions Limited for personal emails.
ROOM Solutions Ltd, http://www.roomsolutions.net
********************************************************************

New Agents being Tested for Neural Burning and Neuropathic Pain


Agents that may soon be available for the treatment of neuropathic
pain and neural burning include: 1) butyl–para–aminobensoate
(Butamben®), an ester local anesthetic, 2) bupivacaine
microspheres,and  3) SNX–III, a selective calcium channel blocker.
Nicotinic acetylcholine receptor agonists such as ABT–594, which may
also prove efficacious, are in preliminary research stages. Animal
studies have revealed the following as potential therapies in
neuropathic pain 1) electroconvulsive treatment 2) intrathecal
injection of chromaffin cells 3) inrathecal injection of Nitric
oxide synthase inhibitor L–N––G–nitro arginine methyl ester (L–NAME)
4) intrathecal neostigmine. A clinically available agent which is
currently being investigated for the treatment of neuropathic pain
is levodopa.


Regards,

Geoffrey
______________________________

Dr. Geoffrey Nase
Ph.D. Microvascular Physiologist
http://www.drnase.com
______________________________

Hi everybody,

I've got some improtant questions about IPL and would REALLY
appreciate it if anyone who has experience with IPl would inform me
about this.

I've been struggling with rosacea for 5 years now and my life has
become a hellthe last year(am 25 now, student in Holland). Lately
it's getting really bad. I can't use anything on my face anymore and
am flushed very often. It's painful and my skin get's more and more
dry, since I can't moisturize it anymore (burns too much). Moxonidine
helps to reduce the flushing a bit, but makes me too dizzy. I flush
soo often and it hurts so much. I can't life a normal life anymore
and my skin seems to get more thin and sensitive with time I feel.
I've had contact with docter Patterson in the UK and he is willing to
treat me, but I would like to know soemthing from someone who has
already been treated.

Could you maybe tell me something about your experiences?

-My skin is extremely dry and sensitive: does IPL in the long run
decrease this in your experience? And can I expect it to get worse
and more irritated at first?

-For a while I had lots of papulas and infections, but lately it has
calmed down a bit. Does IPL make this worse in the beginning? I'm
scared I might have a more irritated and sensitive skin and not
beying able to calm it down.

-I've got seb derm as well: does IPL make that worse?

-Has anyone experienced his or her skin to become less sensitive in
the long run after IPL?

Would LOVE to hear about your experienceS, since this seems tio be
the biggest thing I will have to do in years and I would love to be
well informed.
Thanks, natalja Oosterbaan, Holland.

I have the same question, but different skin issues. I have dry, sun
damaged skin. I'm dying to use the cool new "anti- aging" products
(yes I know, no retinols <ugh!>) but I don't know what, if anything
is appropriate for my rosacea skin. I have got the cleansing part
down, but after that what? The metro gel? Then what? Moisturize I
guess, but are the new products out of the question? Any word on Olay
of Olay regenerist line? Wrinkles or redness, this is my dilemma.

Has anyone experienced increased acne while beginning the acnelamp?
Does acne get worse before it gets better?
Any info would be appreciated?
Tracey

I can't even tell you how excited I am to hear this news!  My face
has been buring a lot lately and I was wondering if there would
ever be some kind of cream I could try.  Will it work? Who knows,
but it's worth a shot and the pay off could be tremendous for us.

Thank you Dr. Nase for doing what you do!

Tricia



--- In rosacea-support@yahoogroups.com, "drnase2000" <
drnase1000@h...> wrote:
>
>
> Neural Burning Treatment Options
>
> Hello Group,
>
> I just got off the phone with the head pharmacist at Community
Drug
> Compounding Pharmacy.  Her name is Susan Marrenthin.  I
detailed
> some of the latest research on topical treatments for neural
pain,
> neural burning, sensory burning and discussed rosacea with
her in
> depth.
>
> Basically, there are three well known prescription-based
topicals
> that have been shown in clinical studies to relieve neural
burning
> and pain sensations, each based on a different mechanism.
>
> 1.  6% Gabapentin in an emollient cream base for sensitive
skin (not
> PLO base)
> 2.  2% Amitryptilline in an emollient cream base for sensitive
skin
> (not PLO base)
> 3.  2% Clonidine in an emollient cream base for sensitive skin
(not
> PLO base)
>
> Community drug makes all three of these creams and places
them in 30
> 1ml syringes (30 grams per month) so the patient can
dispense it
> directly into the hand via syringe with the exact amount needed
> without overdoing it.  The syringes also keep the medication
fresh
> and keep them from oxidizing (most compounding
pharmacies just place
> the cream into large jars that are open to the air and you scoop
out
> the cream with your hand).  The base is very rosacea friendly
> without alcohols or major penetration enhancers.
>
> We spoke in-depth about rosacea neural pain and her
specialty is in
> the treatment of different forms of neuropathic pain.  There are
> many ways that she can make this up for rosacea sufferers.
>
> 1.  Each one individually as detailed above.
> 2.  An elegant mixture of all three (6% Gabapentin, 2%
> Amitryptilline and 2% clonidine in one emollient cream)
> 3.  A combination of all three with a patented form of alpha
lipoic
> acid compounded into the cream.
>
>
> The cost for a one month supply would run $50 to $80 (for 30
> grams).  This is a very reasonable price and may be covered
by some
> insurance companies.  You should apply the cream one to two
times
> daily and if they are going to have a positive effect one should
> start noticing improvement within 45 to 60 days.
>
> If you have neural rosacea pain, then these may be worth a try.
You
> can get a script made out from your doctor and send it in to
> community drug.com.  But the only problem is that the
Pennsylvania
> regulations state that they cannot fill scripts outside the USA.
> So, I spoke to her about this problem.  She knows an online
medical
> physician who dispenses scripts to all over the world.  The
> physician works at medicalwellnesscenter.com.  A patient
outside the
> US would be charged a one time consultation fee and the
script would
> be sent directly to community drug and then shipped out to
you.  I
> have no idea how much shipping is though or the online
consultation
> for 6 refills..
>
> This is not set up yet.  Community drug is going to get in touch
> with the physician this week and set up the above mentioned
script
> options so the physician can basically just OK the script and
send
> it to community drug after a brief medical history online.
>
> I will contact the group once this system is set up.  You can
start
> out conservatively by trying only one of the compounds or try
the
> three compound cream with or without alpha lipoic acid.  The
> interesting thing about the three pronged combination is that
they
> each have a different mechanism of action and therefore has a
much
> better potential for relieving neural burning because peripheral
> sensory burning involves several pathways.
>
> Let me stress something.  I am in no way affiliated with the
online
> drugstore or online physician.  I don't make a single penny off
of
> anything, nor do I get recognition or anything out of this.  I just
> wanted to make these treatments available to everyone in a
user
> friendly fashion (e.g. everything online) without any boundaries
> outside the US.  I also wanted to remove the inevitable
frustrating
> debates with physicians who don't know much about rosacea
and are
> not willing to prescribe anything other than metrogel.
>
> You will need to monitor your heart rate and blood pressure as
> clonidine may lower the blood pressure slightly in a small
(less
> than 5% chance) group.
>
> I will keep everyone updated.  I hope this ends up helping
some.
>
> Onwards and Forwards,
>
> Geoffrey
> ______________________________
>
> Dr. Geoffrey Nase
> Ph.D. Microvascular Physiologist
> http://www.drnase.com
> ______________________________

--- In rosacea-support@yahoogroups.com, "antonio32ca" <tdeto@w...>
wrote:
>
>
> Just wondering if its safe to work out
> with weights (nothing major)just a 30 min
> workout 3x a week while taking 10mg 3x a week?
> thanks.


No probelmo.  Go for it.

Regards,

Geoffrey
______________________________

Dr. Geoffrey Nase
Ph.D. Microvascular Physiologist
http://www.drnase.com
______________________________

This is for Michelle, who inquired about Cetaphil Daily Faicial
Moisturizer SPF 15, taken from www.cetaphil.com
Cetaphil® Daily Facial Moisturizer SPF 15 with Parsol® 1789
Cetaphil Daily Facial Moisturizer SPF 15 with Parsol 1789 Two in one!
Advanced sun protection plus elegant facial moisturizer.

Cetaphil® Daily Facial Moisturizer SPF 15 with Parsol® 1789 and
octocrylene is specially formulated to be highly effective, light and
cosmetically pleasing to the face. Plus, it offers an added bonus –
advanced protection against damaging UVA and UVB rays. This is very
important because the average person is exposed to 18 hours of UV ray
exposure each week from simple activities such as walking to work. It
also helps to prevent premature aging, by reducing the appearance of
fine lines and wrinkles and preventing future sun damage to your skin.
This moisturizer is lightweight, silky-smooth, fragrance-free and
suitable for use under makeup or after shaving. Provides gentle
moisturization for all skin types.

Ingredients: Avobenzone, Octocrylene, Purified Water, Diisapropyl
Adipate, Cyclomethicone, Glyceryl Stearate (AND) PEG-100 Stearate,
Glycerin, Polymethyl Methacrylate, Phenoxyethanol, Benzyl Alcohol,
Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Tocopheryl Acetate,
Caroborner 940, Disodium EDTA, Triethanolamine.
Clare

I have tried manythings including ets/medication/topicals for
blushing/flushing.  I am ready to try a laser.  Can somebody clue me
in on which is the best type for intense flushing associated with
rosacea.  I also am developing a permanent redness.  I would really
appreciate it.  Also, if anybody has any idea on the best setting, or
best dr.  Dr. Nase has already posted the name of a good vbeam dr. in
the indy area.

Thanks so much,
gsrandal

Looks like the good doctor may be willing to work with us.  She just
emailed me the note below.


Dear Dr. Nase,

Susan Merenstein from Community Drug contacted me in regards to your
research activities on Rosacea.  I am a physician and do online
prescribing for a very limited number of medications for benign
recurring  or chronic previously diagnosed conditions.  In addition
I work in preventive and alternative medicine and skin care via  a
Medical Spa so I deal with Rosacea patients.

I am very interested in your work and would possibly consider
working with you as described by Susan from Community Drug.  Please
email me more information about your research and include a
curriculum vitae.

Look forward to hearing from you.

Sincerely,
Joan Katz, MD

Has anyone heard of  a Dr. Roy G. Geronemus in NYC? I heard he was
pretty good. Does anyone have an opinion to share?











--- In rosacea-support@yahoogroups.com, "drnase2000"
<drnase1000@h...> wrote:
>
>
> > Hi,
> >
> > I have rosacea & I am going for a consultation with this Dr. next
> > week.  I was wondering if anyone has ever seen her before for
> > photofacial sessions?
> >
> > Thanks
> > Marianne
>
>
> Hello,
>
> In my opinion, one of the better practitioners that you could see.
> Very dedicated.
>
> Regards,
>
> Geoffrey
> ______________________________
>
> Dr. Geoffrey Nase
> Ph.D. Microvascular Physiologist
> http://www.drnase.com
> ______________________________

--- In rosacea-support@yahoogroups.com, "Beth Adams" <badams01@r...>
wrote:
>

Dr. Nase,

I would like to second what Beth said.  Thank you for taking time out
of your busy schedule to help those of us with neural burning.  I
appreciate all of the information you have been posting lately on the
subject.  We are all very grateful to you.

Sincerely,

Patty



> Dr Nase,
>
> I just wanted to thank you sincerely for taking what must have been
a
> considerable amount of time in your day to help those who have the
pain
> aspect of Rosacea.
>
> Knowing that you have gone the extra mile without expecting a thing
in
> return is the true measure of a friend.
>
> With gratitude,
> Beth
>
>
>
>  ----- Original Message -----
> From: "drnase2000" <drnase1000@h...>
> To: <rosacea-support@yahoogroups.com>
> Sent: Tuesday, October 19, 2004 3:57 PM
> Subject: [rosacea] Neural Burning Treatment Options for Rosacea
Sufferers
>
>
> >
> >
> >
> > Neural Burning Treatment Options
> >
> > Hello Group,
> >
> > I just got off the phone with the head pharmacist at Community
Drug
> > Compounding Pharmacy.  Her name is Susan Marrenthin.  I detailed
> > some of the latest research on topical treatments for neural pain,
> > neural burning, sensory burning and discussed rosacea with her in
> > depth.
> >
> > Basically, there are three well known prescription-based  topicals
> > that have been shown in clinical studies to relieve neural burning
> > and pain sensations, each based on a different mechanism.
> >
> > 1.  6% Gabapentin in an emollient cream base for sensitive skin
(not
> > PLO base)
> > 2.  2% Amitryptilline in an emollient cream base for sensitive
skin
> > (not PLO base)
> > 3.  2% Clonidine in an emollient cream base for sensitive skin
(not
> > PLO base)
> >
> > Community drug makes all three of these creams and places them in
30
> > 1ml syringes (30 grams per month) so the patient can dispense it
> > directly into the hand via syringe with the exact amount needed
> > without overdoing it.  The syringes also keep the medication fresh
> > and keep them from oxidizing (most compounding pharmacies just
place
> > the cream into large jars that are open to the air and you scoop
out
> > the cream with your hand).  The base is very rosacea friendly
> > without alcohols or major penetration enhancers.
> >
> > We spoke in-depth about rosacea neural pain and her specialty is
in
> > the treatment of different forms of neuropathic pain.  There are
> > many ways that she can make this up for rosacea sufferers.
> >
> > 1.  Each one individually as detailed above.
> > 2.  An elegant mixture of all three (6% Gabapentin, 2%
> > Amitryptilline and 2% clonidine in one emollient cream)
> > 3.  A combination of all three with a patented form of alpha
lipoic
> > acid compounded into the cream.
> >
> >
> > The cost for a one month supply would run $50 to $80 (for 30
> > grams).  This is a very reasonable price and may be covered by
some
> > insurance companies.  You should apply the cream one to two times
> > daily and if they are going to have a positive effect one should
> > start noticing improvement within 45 to 60 days.
> >
> > If you have neural rosacea pain, then these may be worth a try.
You
> > can get a script made out from your doctor and send it in to
> > community drug.com.  But the only problem is that the Pennsylvania
> > regulations state that they cannot fill scripts outside the USA.
> > So, I spoke to her about this problem.  She knows an online
medical
> > physician who dispenses scripts to all over the world.  The
> > physician works at medicalwellnesscenter.com.  A patient outside
the
> > US would be charged a one time consultation fee and the script
would
> > be sent directly to community drug and then shipped out to you.  I
> > have no idea how much shipping is though or the online
consultation
> > for 6 refills..
> >
> > This is not set up yet.  Community drug is going to get in touch
> > with the physician this week and set up the above mentioned script
> > options so the physician can basically just OK the script and send
> > it to community drug after a brief medical history online.
> >
> > I will contact the group once this system is set up.  You can
start
> > out conservatively by trying only one of the compounds or try the
> > three compound cream with or without alpha lipoic acid.  The
> > interesting thing about the three pronged combination is that they
> > each have a different mechanism of action and therefore has a much
> > better potential for relieving neural burning because peripheral
> > sensory burning involves several pathways.
> >
> > Let me stress something.  I am in no way affiliated with the
online
> > drugstore or online physician.  I don't make a single penny off of
> > anything, nor do I get recognition or anything out of this.  I
just
> > wanted to make these treatments available to everyone in a user
> > friendly fashion (e.g. everything online) without any boundaries
> > outside the US.  I also wanted to remove the inevitable
frustrating
> > debates with physicians who don't know much about rosacea and are
> > not willing to prescribe anything other than metrogel.
> >
> > You will need to monitor your heart rate and blood pressure as
> > clonidine may lower the blood pressure slightly in a small (less
> > than 5% chance) group.
> >
> > I will keep everyone updated.  I hope this ends up helping some.
> >
> > Onwards and Forwards,
> >
> > Geoffrey
> > ______________________________
> >
> > Dr. Geoffrey Nase
> > Ph.D. Microvascular Physiologist
> > http://www.drnase.com
> > ______________________________
> >
> >
> >
> >
> >
> >
> >
> >
> >
> >
> > --
> > Please read the list highlights and FAQ before posting to the
whole group
> (http://rosacea.ii.net).
> > Yahoo! Groups Links
> >
> >
> >
> >
> >
> >
> >
> >

I have just recently been diagnosed with rosacea (im 24) Right now
my cheeks are just "rosy" and its not that noticeable, but im
starting to notice that i am getting those spider veins in my
cheeks. Will those ever go away without the laser treatment?

Has anyone ever tried B Kamins-Chemist products? They have a rosacea
starter kit that I am interested in trying.

Also, what does everyone do about working out? I love to run and I
dont really enjoy anything else but running....what do runners do to
control the redness after working out?

please help!
Megan

Maize

Kristen,

Most people would think we are 'nuts' to hear we can't eat all those 'healthy'
foods!  Kristen, I was wondering if you  or others had the same problems with
organic fruits or fruits that you know have been vine ripened?  Most of what we
get in the grocery store is ripe when we buy it but it may have been weeks
before that the fruit was picked (unripe) and we would have no way of knowing
it.  I know I have the same issues with peaches and strawberries, on occassion,
.and a few others.  Come to think of it, I had no problems with the strawberries
we picked ourselves last summer. They were perfectly vine ripened and wonderful.
I overate them and feared I would flush but  had no problem.

I seriously wonder if there is a problem with fuits, in general, that have been
picked while unripe for the purpose of shipping.
Possibly drawing at straws!  Perhaps Rosaceans have a sensitivity to this
phenomenon.

Calling Dr. Nase... Do you know anything about this?  Also wondering if you knew
of any studies linking asthma with bananas as I described in previous thread.

Susan in PA
Hi Susan-

Thanks for the educational reply :) ...Maybe it has something to do
with humans only being what is it-3 links in difference to the
banana on the DNA chain-LOL.

Apples..I can see how the sour ones (Macs which happened to be my
fav :(  )and Granny, would cause flushing upon palette contact..Even
Washingtons can be somewhat tart. I seem to be ok with a few raw
slices of Golden Delicious, even some in my cereal. But when I tried
to eat just half of a Roman, I got a terrible flush after it was in
my system. :(

About the only fruit I find safe anymore is blueberries or 1/2 a
pear. I've had to give up all my strawberries and raspberries :(
Peaches make me go hot(high salicylate fruit?)..It has a lot to do
with how much I eat too.Never any whole pieces of fruit :(, just
half. However, just 2 large strawberries and I have an obvious
reaction. Not much left after those since the entire citrus family
is out...It becomes painfully obvious w/nasty flushing, things I
thought I could tolerate as a mild person, such as strawberries,were
a problem all along.

I feel like going equestrian instead of vegetarian because at least
I know oats are safe. Just need to get a feedbag. Some days I look
like Mr. Ed anyway.      A _ A
                                          [(")]
                                            | |
                                           (")
                                           U

take care-
Kristen




--- In rosacea-support@yahoogroups.com, "Susan" <skarppala@a...>
wrote:
>
> Bananas are a trigger not only for Rosacea but also for asthma, as
well.  There was a doctor on the Oprah show many, many years ago
that said that picking them green (in order to ship) makes them
ripen incorrectly.  The molecular structure of the banana cells are
very sharp and somehow perforate the human blood cells when
ingested, which triggers the histamine response, if I remember
correctly.  If bananas are allowed to ripen correctly on the tree
this phenonemon does not occur.  When I stopped eating them a number
of years ago my allergies disappeared! (That was pre-rosacea).  I
now can have an occassional banana but if I eat them two days in a
row, I get terrible flushing.  More often than not I will eat only a
half of banana, maybe once or twice a week or so with no problem.
>
> There might be something to what you say about apples.  I had been
enjoying a reprieve of my rosacea symptoms for a couple of months
now until a good friend gave me a bushel of apples.  The past week
or so I've had flushing and also allergies which I haven't had in a
while.  Could it be because I've been eating a couple of apples a
day????  I won't eat any for a few days and see what happens and let
you know.    What a cruel joke it will be if it is true.  I love
apples!  I also suspect the spices in apple pie including, cinnamon,
cloves and ginger may also be culprits.
>
> Susan in apple country, PA



---
Outgoing mail is certified Virus Free.
Checked by AVG anti-virus system (http://www.grisoft.com).
Version: 6.0.778 / Virus Database: 525 - Release Date: 10/15/2004


[Non-text portions of this message have been removed]

> Hi,
>
> I have rosacea & I am going for a consultation with this Dr. next
> week.  I was wondering if anyone has ever seen her before for
> photofacial sessions?
>
> Thanks
> Marianne


Hello,

In my opinion, one of the better practitioners that you could see.
Very dedicated.

Regards,

Geoffrey
______________________________

Dr. Geoffrey Nase
Ph.D. Microvascular Physiologist
http://www.drnase.com
______________________________

Dr Nase,

I just wanted to thank you sincerely for taking what must have been a
considerable amount of time in your day to help those who have the pain
aspect of Rosacea.

Knowing that you have gone the extra mile without expecting a thing in
return is the true measure of a friend.

With gratitude,
Beth



  ----- Original Message -----
From: "drnase2000" <drnase1000@...>
To: <rosacea-support@yahoogroups.com>
Sent: Tuesday, October 19, 2004 3:57 PM
Subject: [rosacea] Neural Burning Treatment Options for Rosacea Sufferers


>
>
>
> Neural Burning Treatment Options
>
> Hello Group,
>
> I just got off the phone with the head pharmacist at Community Drug
> Compounding Pharmacy.  Her name is Susan Marrenthin.  I detailed
> some of the latest research on topical treatments for neural pain,
> neural burning, sensory burning and discussed rosacea with her in
> depth.
>
> Basically, there are three well known prescription-based  topicals
> that have been shown in clinical studies to relieve neural burning
> and pain sensations, each based on a different mechanism.
>
> 1.  6% Gabapentin in an emollient cream base for sensitive skin (not
> PLO base)
> 2.  2% Amitryptilline in an emollient cream base for sensitive skin
> (not PLO base)
> 3.  2% Clonidine in an emollient cream base for sensitive skin (not
> PLO base)
>
> Community drug makes all three of these creams and places them in 30
> 1ml syringes (30 grams per month) so the patient can dispense it
> directly into the hand via syringe with the exact amount needed
> without overdoing it.  The syringes also keep the medication fresh
> and keep them from oxidizing (most compounding pharmacies just place
> the cream into large jars that are open to the air and you scoop out
> the cream with your hand).  The base is very rosacea friendly
> without alcohols or major penetration enhancers.
>
> We spoke in-depth about rosacea neural pain and her specialty is in
> the treatment of different forms of neuropathic pain.  There are
> many ways that she can make this up for rosacea sufferers.
>
> 1.  Each one individually as detailed above.
> 2.  An elegant mixture of all three (6% Gabapentin, 2%
> Amitryptilline and 2% clonidine in one emollient cream)
> 3.  A combination of all three with a patented form of alpha lipoic
> acid compounded into the cream.
>
>
> The cost for a one month supply would run $50 to $80 (for 30
> grams).  This is a very reasonable price and may be covered by some
> insurance companies.  You should apply the cream one to two times
> daily and if they are going to have a positive effect one should
> start noticing improvement within 45 to 60 days.
>
> If you have neural rosacea pain, then these may be worth a try.  You
> can get a script made out from your doctor and send it in to
> community drug.com.  But the only problem is that the Pennsylvania
> regulations state that they cannot fill scripts outside the USA.
> So, I spoke to her about this problem.  She knows an online medical
> physician who dispenses scripts to all over the world.  The
> physician works at medicalwellnesscenter.com.  A patient outside the
> US would be charged a one time consultation fee and the script would
> be sent directly to community drug and then shipped out to you.  I
> have no idea how much shipping is though or the online consultation
> for 6 refills..
>
> This is not set up yet.  Community drug is going to get in touch
> with the physician this week and set up the above mentioned script
> options so the physician can basically just OK the script and send
> it to community drug after a brief medical history online.
>
> I will contact the group once this system is set up.  You can start
> out conservatively by trying only one of the compounds or try the
> three compound cream with or without alpha lipoic acid.  The
> interesting thing about the three pronged combination is that they
> each have a different mechanism of action and therefore has a much
> better potential for relieving neural burning because peripheral
> sensory burning involves several pathways.
>
> Let me stress something.  I am in no way affiliated with the online
> drugstore or online physician.  I don't make a single penny off of
> anything, nor do I get recognition or anything out of this.  I just
> wanted to make these treatments available to everyone in a user
> friendly fashion (e.g. everything online) without any boundaries
> outside the US.  I also wanted to remove the inevitable frustrating
> debates with physicians who don't know much about rosacea and are
> not willing to prescribe anything other than metrogel.
>
> You will need to monitor your heart rate and blood pressure as
> clonidine may lower the blood pressure slightly in a small (less
> than 5% chance) group.
>
> I will keep everyone updated.  I hope this ends up helping some.
>
> Onwards and Forwards,
>
> Geoffrey
> ______________________________
>
> Dr. Geoffrey Nase
> Ph.D. Microvascular Physiologist
> http://www.drnase.com
> ______________________________
>
>
>
>
>
>
>
>
>
>
> --
> Please read the list highlights and FAQ before posting to the whole group
(http://rosacea.ii.net).
> Yahoo! Groups Links
>
>
>
>
>
>
>
>

Hello All,

I am a 30 year old who has been suffering from Rosacea since my early
twenties and seb derm since my teans.  Like most who suffer from both
know the chemical creams for the sd have some effect on the severity
of rosacea.

I am an active, outgoing person who has been mentally and physically
effected by the pain and loss in confidence in my apprearance. When
my rosacea / sd does clear up with the use of the only thing that has
ever worked, diet and Rosacea LTD III, I am a happier more positive
person.  Being single it is difficult sometimes to be religious about
putting the topical treatment on every night and I know it is not
getting at the root cause.  I have been tested and diagnosed with
food allergies to both eggs and cow's milk. Naturopaths have
suggested that I do not have enough acid in my stomach to kill
bacteria and have prescribed b12 shots etc...

I have cut out caffeine and limit my alchohol consumption and know
and eat all the best foods for rosacea (alkaline vs acidic).

I have been hesitant to go the prescrpiption drug route as I feel
that they may do more harm in the long-run.  I take OPC3, a great
grape seed extract antioxidant in the morning and take esterC, b12,
digestive enzymes, and flaxseed oil daily. Although this more natural
route is my preference I am at a point where I am up for any
suggestions. I have inquired to my GP about accupuncture and if there
has been any studies showing success.  That would be my first choice
before starting Moxonodine,Clarithroymycin or Isotretinoin. Photoderm
or the newer therapy I see written about in this group (photodynamic
tx(sp))would be great but without being covered by insurance it is
not a viable option for me.

I own Dr. Nase's book and find it to be the most comprehensive
definition and treatment guide for Rosacea sufferers. It has helped
me and some of my family members understand my condition.  Family - I
know rosacea runs in my father's family but since they were treated
without any of the antibiotics or chemical creams even in their old
age they are not at the moderate-severe stage of rosacea I am.

Sorry for taking up all of your time with this lengthy cry for help
but I know most of you have some of the same feelings and are the
only people that truly understand.

All the best,

John - Seattle, WA

Neural Burning Treatment Options

Hello Group,

I just got off the phone with the head pharmacist at Community Drug
Compounding Pharmacy.  Her name is Susan Marrenthin.  I detailed
some of the latest research on topical treatments for neural pain,
neural burning, sensory burning and discussed rosacea with her in
depth.

Basically, there are three well known prescription-based  topicals
that have been shown in clinical studies to relieve neural burning
and pain sensations, each based on a different mechanism.

1.  6% Gabapentin in an emollient cream base for sensitive skin (not
PLO base)
2.  2% Amitryptilline in an emollient cream base for sensitive skin
(not PLO base)
3.  2% Clonidine in an emollient cream base for sensitive skin (not
PLO base)

Community drug makes all three of these creams and places them in 30
1ml syringes (30 grams per month) so the patient can dispense it
directly into the hand via syringe with the exact amount needed
without overdoing it.  The syringes also keep the medication fresh
and keep them from oxidizing (most compounding pharmacies just place
the cream into large jars that are open to the air and you scoop out
the cream with your hand).  The base is very rosacea friendly
without alcohols or major penetration enhancers.

We spoke in-depth about rosacea neural pain and her specialty is in
the treatment of different forms of neuropathic pain.  There are
many ways that she can make this up for rosacea sufferers.

1.  Each one individually as detailed above.
2.  An elegant mixture of all three (6% Gabapentin, 2%
Amitryptilline and 2% clonidine in one emollient cream)
3.  A combination of all three with a patented form of alpha lipoic
acid compounded into the cream.


The cost for a one month supply would run $50 to $80 (for 30
grams).  This is a very reasonable price and may be covered by some
insurance companies.  You should apply the cream one to two times
daily and if they are going to have a positive effect one should
start noticing improvement within 45 to 60 days.

If you have neural rosacea pain, then these may be worth a try.  You
can get a script made out from your doctor and send it in to
community drug.com.  But the only problem is that the Pennsylvania
regulations state that they cannot fill scripts outside the USA.
So, I spoke to her about this problem.  She knows an online medical
physician who dispenses scripts to all over the world.  The
physician works at medicalwellnesscenter.com.  A patient outside the
US would be charged a one time consultation fee and the script would
be sent directly to community drug and then shipped out to you.  I
have no idea how much shipping is though or the online consultation
for 6 refills..

This is not set up yet.  Community drug is going to get in touch
with the physician this week and set up the above mentioned script
options so the physician can basically just OK the script and send
it to community drug after a brief medical history online.

I will contact the group once this system is set up.  You can start
out conservatively by trying only one of the compounds or try the
three compound cream with or without alpha lipoic acid.  The
interesting thing about the three pronged combination is that they
each have a different mechanism of action and therefore has a much
better potential for relieving neural burning because peripheral
sensory burning involves several pathways.

Let me stress something.  I am in no way affiliated with the online
drugstore or online physician.  I don't make a single penny off of
anything, nor do I get recognition or anything out of this.  I just
wanted to make these treatments available to everyone in a user
friendly fashion (e.g. everything online) without any boundaries
outside the US.  I also wanted to remove the inevitable frustrating
debates with physicians who don't know much about rosacea and are
not willing to prescribe anything other than metrogel.

You will need to monitor your heart rate and blood pressure as
clonidine may lower the blood pressure slightly in a small (less
than 5% chance) group.

I will keep everyone updated.  I hope this ends up helping some.

Onwards and Forwards,

Geoffrey
______________________________

Dr. Geoffrey Nase
Ph.D. Microvascular Physiologist
http://www.drnase.com
______________________________

There are a few reports at the rosacea treament database:

http://www.rosacea.co.uk

Here are the results of a search just for her reports (using the
search box on the home-page)

http://tinyurl.com/5ztka

Andrew.

--- In rosacea-support@yahoogroups.com, "mariannebadolato"
<mariannebadolato@y...> wrote:
>
>
> Hi,
>
> I have rosacea & I am going for a consultation with this Dr. next
> week.  I was wondering if anyone has ever seen her before for
> photofacial sessions?
>
> Thanks
> Marianne

I'm now very much considering going the low-dose Accutane route
since unfortunately nobody in the Milwaukee area offers the
photodynamic treatment.  Is it okay to do the low-dose Accutane
method if you don't have p & p's?  Also, I have been taking Zoloft
for over a month for depression, but it really doesn't seem like
it's helped that much anyway.  I've heard that Accutane can have
psychological side effects, so does this mean I should go off of the
Zoloft before starting the Accutane?  Thanks!

Hello

I usually throw this out every several months so here goes- can
anyone recommend a good Toronto derm?

Thanks,
Nicole

Hi Dr. Nase:

Just briefly, I joined the group last week and posted for the first
time. Unfortunately I did not receive any responses, so after reading
posts since then, I am trying YOU!  :)

Brief history....have had rosacea for many years (I think!).  I am
36, and have always gotten red in the face after being out in cold
then in warm.  Oddly enough, as a kid, after being in the cold, or
now even cool temps, my feet would numb up, and my hands too, then
they would swell HUGE after coming indoors.  Any relation???

But back to the rosacea, I was sent to a doc. about 6-7 years ago by
ob-gyn as she noticed my red cheeks and wanted me tested for
LUPUS!!!!!!  The doc mentioned rosacea, but I never followed up with
it because I have been pregnant or nursing, dealing with cancer, and
postpartum depression for the better part of the past 8 years.  I was
afraid to use meds, and also afraid of doing more harm than good,
etc.

So I am pretty sure I'm done having babies (#4 sent me through PPD
hell), and I am tired of having to cake on the makeup (I use
prescriptives) just to walk out the door to go to the gym.  I know I
do things that are "triggers" as I have read the list from the
handout from dermatologist.  I exercise, drink hot decaf, occasional
wine or beer, go outdoors without a hat, etc.  And I have faced the
reality that I am not willing to give most of these up.  (I know, I
know).

That being said, I finally went to the derm. who quickly prescribed
doxycycline (200 mg/day) indefinitely, and Finacea.  I have the red
cheeks, my nose flushes, a little reddish bumpiness below my bottom
lip on each side, and I get pustules (?) on my cheeks (little white
easily popped things), mainly the two weeks before my period.  I
balked at the long term use of antibiotics, and she said she's been
taking it for her rosacea for 15 years, but to take 100 mg instead.

I have done a little reading up on this group, but my 4 little kids
and my devotion to helping those women with PPD take up much of my
time.  I did read that the Finacea won't help with the redness.  I
also read that once you start the antibiotic, if you stop the rosacea
will come back WORSE!!!!  I am opposed to having to take antibiotics
forever.  So I am looking for a place to start.  I have seen people
talk about the rosacea disks, the zinco, etc.  I am so confused that
I simply do NOTHING!!!  I am afraid that I have already let it go too
long without doing anything and have caused more damage.

Can you possibly give me some guidance as to where I should begin?
Do I do the treatment she prescribed?  What about cleansers and
moisturizers?  Also, makeup/coverup that covers but looks natural,
but also lasts?  She sent me to her estheti. who gave me samples of
Toleraine wash and cream.

I truly appreciate your time and dedication to this cause.  Thank you
so much.

Wendy

I'm talking about photodynamic treatment, not photoderm.  Thanks anyway.

Laura <laura@...> wrote:


hello there, i have had such incredible success with photoderm
for my rosacea.

i googled 'laser, vein, photoderm, and wisconsin', and came up
with

http://www.lasercentersofwi.com/how.html

click on 'photorejeuvenation' on the left!!!

Laser Centers of Wisconsin
5201 North Port Washington Rd.
Milwaukee, WI 53217 ·
ph 414.963.0275 ·
fx 414.963.0667 ·
800.821.5532 in Wisconsin only

cheers,
Laura in NC








--
Please read the list highlights and FAQ before posting to the whole group
(http://rosacea.ii.net).
Yahoo! Groups Links









__________________________________________________
Do You Yahoo!?
Tired of spam?  Yahoo! Mail has the best spam protection around
http://mail.yahoo.com

[Non-text portions of this message have been removed]

Just wondering if its safe to work out
with weights (nothing major)just a 30 min
workout 3x a week while taking 10mg 3x a week?
thanks.

Clare,

I know a few people in my office block who use the Rosacea-ltd disks
with good results. Can you tell me more about the Cetaphil
Moisturizer? Do you know the ingredients? I like the cleansing bar,
but I haven't seen the moisturizer in my area.

Michelle

--- In rosacea-support@yahoogroups.com, "Clare" <cslavor@b...> wrote:
>
>
> Pinal - I've been using Rosacea LTD discs for about 4-5 yrs.  I am
a
> fair skinned redhead, and nothing I'd tried from the dermatologist
> worked for the long term (metrogel, metrocreme, antibiotics).
Rosacea
> LTD has kept my redness to a minimum.  For me, it has been like a
> miracle.  I combine this w/Cetaphil Gentle Cleansing Bar (soap) and
> Cetaphil SPF 15 moisturizer.  This regime works for me.  Good
luck.
> Clare in Louisiana

Hi Dr. Nase,

I had an IPL treatment four days ago (this past Friday).  I am
getting increasingly concerned about the condition of my skin since,
as I had four treatments from the same doctor in the past using
almost identical settings (570 filter, single pulse, 47 J +/- 0.5 J)
with nowhere near the reaction I'm currently getting.  In the past, I
had significant swelling lasting for several days, moderate redness
that faded rapidly after two or three days, and some increased
bumpiness.  This time, I had swelling but it was much milder and is
now nearly gone, but the intense redness has only faded maybe 5%, and
I had the bumpiest skin I could ever imagine (though that has now
faded by about 75%).  I had no obvious blistering, but everything
just looked burnt to me.  Everyday that I awake and see that the
redness has not faded leaves me more concerned.  In addition, the
itchiness and inflamed feeling is driving me nuts, and even woke me
up last night.  Basically I'm concerned because I've had nearly
identical treatments in the past with nowhere near the post-treatment
problems I'm having now.  Those treatments turned out to be very
helpful, and I had high hopes going into this next round, but I'm
currently very concerned over what I'm experiencing, and I'm just
praying I didn't pay to have things made worse.

First off, do you have any thoughts about my scenario and what's
going on?  Second, is there anything I can safely use to take the
edge off the itchy and inflamed state that my skin is currently in?

Many thanks,
Brad

Hi,

I have rosacea & I am going for a consultation with this Dr. next
week.  I was wondering if anyone has ever seen her before for
photofacial sessions?

Thanks
Marianne