Hi Matt,

I did some searching, but couldn't find anything on B.Oleronius and
porphyrins either. I also did a search on the species and porphyrins
but did not find anything that would indicate that all members of the
species would contain porphyrins...

Dan

--- In rosacea-support@yahoogroups.com, Matthew I <mtthw_i@...> wrote:
>
> Hi Dan,
>
> Yeah that confirms a few things.
>
> When i was trying to find whether B.Oleronius contained naturally
occuring Porphyrins, I couldn't find any matches, so did a quick
search to find if other Negative Gram bacteria contained Porphyrins,
but it seems to vary.
>
> I think it is established that the production of singlet oxygen
produced by the light reacting with the porphyrin is destructive to
the bacteria, However I cannot locate if porphyrin is naturally
occuring in B.Oleronius. Any ideas there?
>
> Yeah i share your concern about the statement that had the words
"Proliferative" and "Pseudomonas aeruginosa" in the same sentence.
With consideration to the fact that it is apparently an opportunistic
bacteria that thrives in burns, wounds and cuts.
>
> http://textbookofbacteriology.net/pseudomonas.html
>
> One of the major marketed uses of LED therapy is for wound healing.
If it could possibly have a proliferative affect on some form of gram
negative bacteria this could be a problem.
>
> Matt.
>
>
--------------------------------------------------------------------------------\
----------------
>
> Hi Matt,
>
> Thanks for posting this info. I found it very interesting,
> particularly since most articles I've read haven't mentioned naturally
> occuring porphyrins in bacteria, but rather concentrate on application
> of additional porphyric substances in addition to light therapy.
>
> I couldn't dig up too much more that helped explain this, but here's
> an article discussing light therapy (mostly laser, but again, I don't
> think the light source is all that important here) and porphyrins.
> It explains pretty well how they work together, namely, "Light energy
> is absorbed by bacterial porphyrins, triggering production of toxic
> singlet oxygen which damages or destroys the bacteria":
>
> http://www.shorelas er.com/LaserAcne Rx.html
>
> So with your articles and other suggesting that certain bacterial seem
> to have naturally occuring porphyrins, potentially light therapy can
> be antibacterial for these bacteria even without the use of additional
> photoactive substances (like ALA, etc).
>
> Along these lines, the only thing that worries me is the statement
> "all energy densities of Ar ion laser showed a proliferative effect on
> Pseudomonas aeruginosa".
>
> Does this sort of answer your questions? If not, let me know and
> I'll take another stab at answering...
>
> Thanks again...
>
> Dan
>
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>
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>