See the below study, which indicates Demodex is the carrier. I thought this
excerpt was pretty interesting: "typical treatment for rosacea
initially includes oral antibiotics that destroy B. oleronius.
Interestingly, he said, antibiotics that are not harmful to these
bacteria generally are not effective in the management of rosacea. "
-Artist


The role of bacterial antigen(s) in the etiology and persistence of
papulopustular bacteria.
Dr. Kevin Kavanagh, Department of Biology, National University of
Ireland - Maynooth, and Dr. Frank Powell, consultant dermatologist,
Mater Misericordiae Hospital, Dublin.

Bacteria associated with microscopic mites known as Demodex
folliculorum may play a role in the development of papulopustular
(subtype 2) rosacea, according to the results of a study funded by a
National Rosacea Society grant and reported at the 2004 annual meeting
of the Society for Investigative Dermatology.

In the completed study, Dr. Kevin Kavanagh and colleagues found that
the bacterium Bacillus oleronius stimulated an immune system response,
inducing high levels of T-cell proliferation, in 79 percent of
patients with subtype 2 rosacea, compared with only 29 percent of
patients without the disorder. T-cell proliferation induces an
inflammatory response, evident as papules and pustules.

"This indicates that the Bacillus bacteria found in the Demodex mite
produce an antigen that could be responsible for the tissue
inflammation associated with papulopustular rosacea," Dr. Kavanagh
said.

The researchers located the bacteria in Demodex folliculorum, which
are normal inhabitants of human skin. Because these microorganisms
often occur in much greater numbers in patients with rosacea,
researchers have long theorized that they may play a part in the
development of the disorder.

The researchers offered several possibilities that may explain how
Demodex and bacteria interact to cause inflammation in rosacea. The
Demodex mites may carry the pathogenic bacteria into areas of the face
susceptible to the changes of rosacea, so that the increased mite
density in rosacea patients may result in a higher density of bacteria
that produce the papules and pustules. Alternatively, Demodex mites
may be attracted to an area of facial skin rich in these bacteria and
increase in numbers in this "fertile territory."

Another possibility is that the mites in rosacea patients are infected
with these bacteria, which in turn produce stimulatory antigens that
trigger the disorder in susceptible patients.

Dr. Kavanagh noted that the potential role for bacteria in causing
papulopustular rosacea is supported by the fact that typical treatment
for rosacea initially includes oral antibiotics that destroy B.
oleronius. Interestingly, he said, antibiotics that are not harmful to
these bacteria generally are not effective in the management of
rosacea.

Moreover, the possibility that antigens may play a role in disease
processes has been demonstrated in other disorders. For example,
antigens produced by Streptococcus and Staphylococcus bacteria have
been linked with such disorders as psoriasis, food poisoning and toxic
shock syndrome.

Dr. Kavanagh and his colleagues are now developing antibodies against
the antigen produced by B. oleronius to confirm its presence on the
faces of patients with papulopustular rosacea and to define its
relationship with Demodex mites.



--- In rosacea-support@yahoogroups.com, Matthew I <mtthw_i@...> wrote:
>
> Did a little more research. Unfortunately without more background
knowledge it's only speculation, but seems to be heading somewhere.
>
> There is a gram negative bacteria found within the Demodex Mite
called Bacillus Oleronius.
>
>
> The following is an article on LLLT and Gram Negative Bacteria. It
mentions two other types of Bacteria, being the Gram Negative
Pseudomonas aeruginosa and the Gram Positive Staphylococcus aureus.
>
> They classify the difference as follows. Gram-negative bacteria are
those that do not retain crystal violet dye in the Gram staining
protocol. Gram-positive bacteria will retain the dark blue dye after
an alcohol wash, whereas Gram-negative bacteria do not. In a Gram
stain test, a counterstain is added after the crystal violet, which
colors all Gram-negative bacteria a red or pink color. The test itself
is useful in classifying two distinctly different types of bacteria
based on structural differences in their cell walls.
>
> Here is a quote…
>
> "All energy densities of Ar ion laser showed a proliferative effect
on Pseudomonas aeruginosa and inhibitory effect on Staphylococcus
aureus. Similarly, SHG Nd:YAG and He-Ne lasers with chosen energy
densities were again proliferating for Pseudomonas aeruginosa and
inhibitory for Staphylococcus aureus"
>
> http://www.springerlink.com/content/e072158g52487462/
>
> This shows that LLLT definitely has an affect on Gram-Negative/
Positive bacteria.
>
> Unfortunately you have to purcahse the article to see it in its
entirety. If you look at the google search though it mentions
something about Gram negative Bacteria with higher amounts of
porphyrins, so it gives a teaser to possibly releasing some
information there.
>
> http://www.google.com.au/search?hl=en&q=gram-
negative+bacteria+respiratory+chain+porphyrin&meta=
>
>
> This article mentions Bacillus, Porphyrin and respiratory chain but
there was soo much medical jargon it was hard to put it all together.
Maybe Dan could decipher this one for us if he has a spare minute?
>
> http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=197023
>
>
> This article from the Rosacea Archives relates a possible cause to
Bacillus Oleronius also.
>
> http://www.rosacea.org/press/archive/20040503.php
>
> Hmm, All I can add is that LLLT definitely has an affect on
bacteria. But for Bacillus Oleronius specifically though, I am
unsure.
>
> Matt.
>
> -------------------------------------------------------------
>
> Matt wrote: "I did some quick googling but couldn't find what the
demodex mite uses for its respiratory chain."
>
> Hi Matt,
>
> Thanks for your contribution to the discussion on this topic, which
was of course rather more detailed than the snippet above. ;)
>
> I wonder if anyone else might like to take up the challenge and
locate a study with this information? You never know, someone might
have a bit of time on their hands and want to demonstrate their
superior abilities with search engines. No harm in cautious optimism,
is there? :)
>
> Kind regards,
>
> Aurelia
>
> Send instant messages to your online friends http://au.messenger.
yahoo.com
>
> [Non-text portions of this message have been removed]
>