Hello Group,

I am currently on the editorial staff of four peer-reviewed
dermatological journals. I review mostly rosacea articles and acne
articles. Anyway, I have been inundated with 9 new manuscripts on
the role of demodex in rosacea. 7 out of the 9 manuscripts are very
well done.

I believe that most people know my feelings on the role that demodex
play in rosacea -- minimal to none. However, as a medical scientist
I must continue to keep my eye open and perform research without
bias. I am realizing that in a significant portion of rosacea
sufferers (possibly 30% to 40%) that demodex may play a secondary
role in rosacea symptoms. They are NOT the underlying cause of
rosacea, but they can cause papules, pustules, itchiness, extreme
skin hypersensitivity, cosmetic intolerance syndrome, folliculitis,
burning, chronic facial redness and increase the intensity/duration
of flushing.

What has changed my mind? The above mentioned studies. Oral
treatment with an anti-mite drug has resulted in substantial
improvement in all the above symptoms in approximately 40% of the
cases (several hundred cases within the 9 articles). They are not
using topical sulfur, Eurax or permetherin because it takes a long
time to kill the mites topically and the inactive ingredient bases
are usually quite irritating and very drying.

Oral Ivermectin (Stromectol) is making a huge difference in these
sufferers facial symptoms and flushing triggers (yes, I said
flushing triggers). Ivermectin is an anti-mite drug that is related
to the macrolide antibiotics. It has a very good safety profile and
less side effects than most antibiotics (and not one major side
effect). In addition, the treatment regimen is so simple and it can
be used for treatment and diagnoses:

Treatment Regimen:

For patients under 100 pounds -- 6 mgs per day with food. For
patients over 100 pounds -- 12 mgs per day with food.

Treatment of Mild Demodex Infestation: One single treatment every 6
months

Treatment of Moderate Demodex Infestation: One treatment every week
for 4 weeks. This is followed by one single treatment every 6
months.

Treatment of Severe Demodex Infestation: One treatment every day
for two weeks. This is followed by one single treatment every 6
months.


It is quite inexpensive and may be worth a try for those who are not
responding to other treatments or have angry face sydrome or severe
skin hypersensitivity. You know who you are.


Regards,

Geoffrey
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Dr. Geoffrey Nase
Ph.D. Microvascular Physiologist
http://www.drnase.com
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