Many patients with rosacea are unable to tolerate extended treatment periods
with
topical agents because of the unusually high skin sensitivity that often
accompanies
rosacea. Kinetin (N(6)-furfuryladenine) is a plant cytokinin that reportedly
helps restore
skin barrier function and may be useful to ameliorate the signs and symptoms of
rosacea. The purpose of this open-label study was to determine the tolerance and
efficacy of twice-daily application of kinetin 0.1% lotion for improving the
signs
and symptoms of mild to moderate facial rosacea. Subjects applied kinetin 0.1%
lotion
twice daily to the face, with daily use of a sunscreen of sun protection factor
30.
Subjects were evaluated at baseline and at 4-week intervals for 12 weeks to
assess
efficacy and tolerance. Results of this study suggest that kinetin 0.1% lotion
is a well-
tolerated moisturizing lotion option for subjects with mild to moderate
inflammatory
rosacea.

For more info:

http://members.rosacea-research-and-development-institute.org/index.php?
showtopic=400