For Everyone,
When I cured the "stealthy" infestation on the back of my left hand, (with [DMSO
+ 1% fluconazole]), and later cured the back of my right hand, (with [DMSO + 10%
fluconazole]), one important question occurred to me that I've never been able
to answer well. The question:
"Why should we even bother to cure a 'stealthy' infestation, that is basically
invisible, and never seems to give us much 'trouble'?"

Recently, I found a possible answer. The nature of "fungal infestations" is
that they commonly produce "mycotoxins", which serve to "digest" the nutrients
surrounding the fungi.
So we are led to ask:
"What will the effects be, if such "fungal infestation" mycotoxins end up in our
bloodstream, and throughout our body, for years or even for decades?"
I touch on the answer to this question, in the following recent private email
exchange, and it may surprise everyone. If this "Theory of Mechanism" proves to
be valid, the curative power of [DMSO + fluconazole] will certainly range far
beyond our original expectations.
God Bless, ITN & IDFN,
Dave Fleming ---TEXT OF EMAILS FOLLOW, (in reverse chronological order)-------

Dave Fleming wrote:
Hi, [name deleted],
Thank you for the compliment of your interest in my input.
I deeply appreciate your apparent trust of my opinions, but I have to report to
you that I am a "layman", with very little "absolute knowledge" about this.
Experience is my strong point in this matter of curing rosacea with [DMSO +
fluconazole].

I like to point out facetiously, that, because of some experience in my
background in pharmaceutical laboratory research with animals, (in which I
became a fairly proficient heart surgeon), I know just enough to make me
dangerous. I am therefore certainly not in the usual "awe" of the "white
coats", with their self-serving, pretentious, and usually obfuscating jargon.
:-)

But I would like to cut to the chase, and wonder with you and your colleagues,
exactly what is the "ROOT CAUSE" of rosacea? Knowing this "ROOT CAUSE" would,
of course, make any "opinions", about IPL/laser, Accutane, (or even [drug name
deleted], whatever that is), much more trustworthy. As long as we're in the
dark, concerning the "ROOT CAUSE" of rosacea, it seems to me that our "opinions"
about how to best get rid of it are almost moot, especially given the fact that
no one has been able to guarantee getting rid of anyone's rosacea, much less all
rosacea.

That's why I consider my "accidental" experience with [DMSO + fluconazole] to be
so revolutionary, revealing and valuable. I tried to describe it, at:
http://groups.yahoo.com/group/rosacea-cure/message/2
When I started posting this claim, in April 2003, I couldn't even spell
"rosacea" correctly.
Knowing what little I do, I've always resisted the urge to insist that rosacea
is "fungal based", because the bottom line is that we cannot know that 100%,
just because an antifungal with a mysteriously penetrating "DMSO vehicle" cured
my rosacea/rhinophyma. And besides, we never HAVE to know how it "works", to
cure all rosacea.

But it's a pretty easy and reliable sounding assumption to reach.
That leaves us wondering why no one, (apparently), has ever been able to
"detect" the "rosacea causing fungal entity". But fungi, [fun-ji], are so
diverse and powerful, that it should not surprise us if their hyphae, [hi-fee],
are so "fragile" as to escape detection by gross microscopy.

So, we have a cure for rosacea, (i.e. topical, {and probably also oral}, [DMSO +
fluconazole]), but we don't really know for sure why or how it is "working",
although even any fool should conclude that some sort of "fungal, parasitical
entity" is the "ROOT CAUSE".
Voila, a fait accompli (!!!)

So, I would hope that we can all agree that any "discussions" of "rosacea
remedies" such as IPL/laser, or Accutane, or [drug name deleted], have become
academic, in the light of this [DMSO + fluconazole] cure for rosacea.

The fact that this [DMSO + fluconazole] cure is excruciatingly slow, cumbersome,
and psychologically problematic, (since our face will look worse, before it
looks better), is admittedly slowing its acceptance, but I feel that the truth
will out. And if necessary, we will use [DMSO + fluconazole] just as we used
Aspirin for so many decades, without ever understanding its "pharmacological
mechanism(s)" in the least.
(1) "Oh, Aspirin gets rid of fever and relieves pain? Great! Take it, even
though we don't know how it works!"

(2) "Oh, [DMSO + fluconazole] gets rid of rosacea/rhinophyma, and tinea
versicolor, and ringworm, and athlete's foot, and nail fungus, and God knows how
many "non-specific" stealthy skin and other diseases that have been incurable
since time immemorial? Great! Pour it on, even though we don't know how it
works!"

And, as Aspirin did, which was a coal tar derivative "accidentally" found to
"work", [DMSO + fluconazole] has, (since Jan. 2004), escaped Pfizer's (17
year?) patent, and is as we type becoming more and more dirt-cheap, worldwide.
And DMSO has always been relatively cheap. :-D

The best opinion I've gathered, about Accutane, is that it has horrific side
effects, that caused one fellow cured by Dr. Syrokomsky to call it "rat poison".

IPL/laser is simply no more nor less than a burning of the skin, so I fail to
see any integrity in its use, (to "treat" rosacea), and my opinion is that it is
making a whole lot of bamboozling folks a whole lot of money, with the guarantee
that rosaceans will have to keep coming back for more, until the day they die,
still having rosacea.

I look forward to seeing that article you found, stating that the "oral azoles"
had a positive effect on SD and rosacea. However, remember that the "oral
azoles" have some horrific potential side effects. Not the least of these, is
an "endocrine effect", (especially attributed to ketoconazole, but none to
fluconazole), which makes men grow breasts and causes women to have
gynecological problems.

Permanent liver damage and death are also expected side effects, with high doses
of the "oral azoles".

Fluconazole appears to be best known as the "azole" with the least side effects,
and doctors have continued to increase the acceptable dosage, even
astronomically, to 30mg/kg of body weight, per day, if my memory serves me.
(That's 3,000 mg per day, for a 100 kg guy!!!) The absolute maximum acceptable
dose of fluconazole at first was 400 mg per day.

Topical [DMSO + fluconazole] is looking better and better, eh, [name deleted]?
In fact, even oral [DMSO + fluconazole] is fine, since most of the med will be
"trapped", (by the "reservoir effect" of DMSO), in the tissue it contacts, with
only less than 10% entering the bloodstream, to have beneficial, healing "whole
body effects", wherever it "discovers" these insidious, parasitical fungi, which
incidentally are very likely to be pouring mycotoxins into our whole bodies,
even though they many times appear "stealthy".

Such chronic, whole-body, low-level, (and therefore impossible to detect),
mycotoxins could very well be responsible for some of the mysterious "chronic
fatigue syndrome(s)" we've been hearing about, as well as for other
unexplainable "diseases". So we can at least strongly suspect that diseases
with no known cause could be caused by the effects and cascade effects of the
mycotoxins any "fungal infestation" in our body would likely produce.

And remember, we do not have to "diagnose" these "stealthy, parasitical, fungal
infestations", to destroy/cure them. [DMSO + fluconazole] is so safe, that it
can be used prophylactically, (i.e. preemptively), to "seek-and-destroy" such
POSSIBLE "infestations". [DMSO + fluconazole] would be administered with the
intention of possibly detecting such "fungal infestations", (as they are cured),
by the "reaction" that occurs in "infested skin", when this med is used.

When I used [DMSO + 10% fluconazole] on my hand, some of the med circulated in
my bloodstream, and I found myself "itching" at more than one place on my left
arm. When I applied the 10% med directly on these "itching spots", I discovered
that I was curing these "infestations" completely. I "self-diagnosed" one of
those spots as tinea versicolor, and it was quite a dramatic cure, with many
"changes" that occurred in the skin, that proved it was cured.

Following is a rudimentary list of "idiopathic" diseases, (i.e. diseases with
unknown causes), that may very well turn out to be curable, by destroying the
ROOT CAUSE "fungal infestations" with [DMSO + fluconazole]:
* Autoimmune disorders:
rheumatoid arthritis, multiple sclerosis, Type 1 diabetes, scleroderma,
myasthenia gravis

* Endocrine diseases

* Syndromes and diseases of unknown etiology, or of mixed causes:
Alzheimer's disease, cancer, hypoglycemia, chronic fatigue syndrome, acquired
neuromyotonia (Isaac's syndrome), Guillain-Barre syndrome, Stevens-Johnson
syndrome, Meniere's disease

* Neurological disorders and mental illnesses:
schizophrenia, bipolar disorder, depression, obsessive-compulsive disorder,
eating disorders, dementia

* Psychogenic illness
multiple chemical sensitivity --- "MCS", mass sociogenic illness, ...

Admittedly, it might be a "stretch", to assert that "fungal infestation" chronic
mycotoxins are the ROOT CAUSE of "mental illnesses", (although it is possible),
but it is quite believable that our immune system could be radically altered by
such chronic low-level mycotoxins, (put out for decades by parasitical fungi
that have already defeated our immune system).
Such undetected, (and probably undetectable), mycotoxins could lead to
autoimmune disorders, and even to other complex damage to our immune system,
which could very well CAUSE "MCS" and other allergy manifestations. This
complex "interplay" of the mycotoxins and our immune systems might also explain
the allergic "triggers" that plague rosaceans.

Incidentally, every surgery or dental procedure that has ever occurred has most
likely introduced these extremely slow-growing fungi into our bodies, with all
the long-term implications of those "infestations". Because they grow slowly,
no one has ever proven that they are "caused" by surgery/dentistry.

Now, if we can overcome the "status-quo juggernaut", that seeks to suppress this
news about [DMSO + fluconazole], we need not live with the damage from that sort
of "infestation" any more. Surgeons may end up routinely using [DMSO +
fluconazole] to prevent such fungal infestations, just as antibiotics are used
now to "pre-empt" potential bacterial infections. Or maybe not, because no
proof exists that [DMSO + fluconazole] would destroy or inhibit "fungal spores".
But "whole body" systemic [DMSO + fluconazole] would presumably work later, to
destroy the growing "fungal entity" in the body.

Thank you for your interest, [name deleted]. I hope you and your colleagues
will be able to promote [DMSO + fluconazole] more effectively than I have.
God Bless, ITN & IDFN,
Dave Fleming
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Date: Sun, 10 Jul 2005 16:56:46 -0700
From: [name deleted]
To: <fulltruth40@...>
Subject: accutane/lasers

Dave,
I believe I read in a dermatology journal that mentioned oral fluconazole,
itraconazole, and oral ketoconazole all had a positive effect on Seborrheic derm
and had potent anti-inflammatory effects helpful for rosacea induced skin.
There are a few links that touch on this but I will try to find you the article
that I read.

Also, in case you were interested, I am involved in a study from [company name
deleted] testing [drug name deleted] for SD and for rosacea. I work with a team
of derms weekly and discuss with them options for rosacea/SD. The [drug name
deleted] is mildly effective in controlling the flaking of the SD, but I think
the topical actually contributes to progressing the rosacea. I would not
recommend it for any rosacean.

Interestingly enough, some of the derms are pro low dose accutane and some are
totally against its use. There is one doc who believes in relatively high
(120mg/d) dose accutane for rosacea. All however, agree that IPL and the use of
lasers for rosacea is counter-intuitive, but I've read of many first hand
accounts that attest to its efficacy.

Your thoughts on accutane and IPL would be greatly appreciated.

Thank you once again for your response and effort in this cause.
[name deleted]
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BEGINNING OF NEXT EMAIL
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Date: Sun, 10 Jul 2005 18:09:39 -0400
From: fulltruth40 <fulltruth40@...>
To: [name deleted]
Subject: RE: rosacea-cure, and SD

Dave Fleming wrote:
Hi, [name deleted],
Thank you for your positive input.
I am quite surprised, at your statement that, "fluconazole has been proven
effective against rosacea in clinical trials".
Do you mean ORALLY ADMINISTERED fluconazole???
I know of no such proof, that ORAL fluconazole CURES rosacea. Do you?
Could you possibly tell me where I can see the evidence of those clinical
trials?
My mind has been very closed to that possibility, because I believe that the
dosage and chronic, long-term use of ORAL fluconazole would have serious side
effects in 100% of all cases.

Furthermore, I am convinced that this "parasitical rosacea entity" is at least
partially "hiding" INSIDE damaged human cells, which would require the DMSO as
the "vehicle" to get the fluconazole where it can CURE ALL the rosacea, since
ORAL fluconazole in the bloodstream cannot get inside the human cells. I spoke
of this at:
http://health.groups.yahoo.com/group/rosacea-cure/message/192
http://health.groups.yahoo.com/group/rosacea-cure/message/193

The possible side effects and normal dosages of fluconazole are at:
http://health.groups.yahoo.com/group/rosacea-cure/message/111
There, they state:
"(3) Dermatologic: Patients have rarely developed exfoliative skin disorders
during treatment with DIFLUCAN/fluconazole. In patients with serious underlying
diseases, (predominantly AIDS and malignancy), these have rarely resulted in a
fatal outcome. Patients who develop rashes during treatment with DIFLUCAN should
be monitored closely and the drug discontinued if lesions progress."

These "exfoliative skin disorders" are listed as possible SIDE EFFECTS of ORAL
fluconazole, which confuses this issue even more.
I am convinced that these "exfoliative skin disorders", LABELED AS SIDE EFFECTS,
may very well be the ORAL fluconazole PARTIALLY FIGHTING many types of "stealthy
parasitical skin diseases", (including rosacea).
But my opinion is that the ORAL fluconazole could NEVER CURE these skin
diseases, because they require repetitious, long-term use of the fluconazole,
which would be toxic to the liver, kidneys, and possibly the whole body, even
causing death. Also, only [DMSO + fluconazole] can penetrate inside the human
cells, to kill ALL the disease, while keeping the systemic levels of fluconazole
extremely low.

~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
Please let me know if your statement that "fluconazole has been proven effective
against rosacea in clinical trials" is a mistake. If it's true, it is a
tremendous shock to me.
~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~

As for your question about "seborrhea", I assume you mean "Seborrheic
Dermatitis".
My opinion, is that [DMSO + fluconazole], (I'm not sure what percentage of the
fluconazole would be best), is most likely the best "treatment", (to get rid of
the symptoms), for SD, which apparently has a strong genetic vector. Because of
this genetic vector, we may have to assume that SD cannot be cured at this time,
until we invent some genetic cure.

I don't know.
I do know of one case of a man who told me that the [DMSO + 1% fluconazole] and
the [DMSO + 10% fluconazole] got rid of his SD symptoms, but they returned
within a week or two, as I remember. I spoke of that, at:
http://groups.yahoo.com/group/rosacea-cure/message/232
Of course, we never know whether what we receive on the Internet is true or not.

If you have very little time, I think my best post on SD was at:
http://health.groups.yahoo.com/group/sebderm/message/2964
http://www.dermadoctor.com/pages/newsletter66.asp?AID=6024

Here are all the posts I've made, on that SD group board:
http://health.groups.yahoo.com/group/sebderm/message/3133
http://health.groups.yahoo.com/group/sebderm/message/2964
http://health.groups.yahoo.com/group/sebderm/message/2391
http://health.groups.yahoo.com/group/sebderm/message/2267
http://health.groups.yahoo.com/group/sebderm/message/2265
http://health.groups.yahoo.com/group/sebderm/message/2223
http://health.groups.yahoo.com/group/sebderm/message/2192
http://health.groups.yahoo.com/group/sebderm/message/2177
http://health.groups.yahoo.com/group/sebderm/message/2175
http://health.groups.yahoo.com/group/sebderm/message/2167

So, I hope this helps. I would appreciate your updating me, in the future, of
your results, and especially what your doctor(s) might say, and especially if
your doctor(s) would "go public" with any positive opinions.
Thank you much, for your positive interest and info.
God Bless, ITN & IDFN,
Dave Fleming
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--- On Sat 07/09, [name deleted]> wrote:
From: [name deleted]
To: fulltruth40@...
Date: Sat, 9 Jul 2005 17:37:44 -0700
Subject: thank you

Dave,
Thank you very much for your response. I've spoken with several MD's who agree
that this treatment makes sense and are willing to prescribe it. I'm uncertain
as to why some have given this such a bad report when fluconazole has been
proven effective against rosacea in clinical trials.
Out of curiosity, do you know how this med acts on seborrhea?
I'm willing to try it and will keep you posted on the results.
Thanks again,
[name deleted]



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