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Hydrocodone is in a group of drugs called narcotic pain relievers. It is similar to codeine. Acetaminophen is a less potent pain reliever that increases the effects of hydrocodone.

Chronic use of Pills can result in tolerance to the medication so that higher doses must be taken to obtain the same effects. Long-term use also can lead to physical dependence—the body adapts to the presence of the substance and withdrawal symptoms occur if use is reduced abruptly.

People become dependent upon Pills for a feeling of well-being and will often get multiple prescriptions from different doctors to support their habit. Addictive drugs activate the brain's reward systems.

The combination of acetaminophen and hydrocodone is used to relieve moderate to severe pain. Medication may also be used for purposes other than those listed in this medication guide.

The ability of addictive drugs to strongly activate brain reward mechanisms and their ability to chemically alter the normal functioning of these systems can produce an addiction.

Do not use this medication if you are allergic to acetaminophen or hydrocodone, or other narcotic pain relievers such as fentanyl (Actiq, Duragesic), hydromorphone (Dilaudid, Palladone), methadone (Methadose, Dolophine), morphine (Kadian, MS Contin, Oramorph, and others), oxycodone (Oxycontin), and oxymorphone (Opana).

Hydrocodone may be habit-forming and should be used only by the person it was prescribed for. Pills should never be given to another person, especially someone who has a history of drug abuse or addiction.

Keep the medication in a secure place where others cannot get to it.

Keep track of how many tablets have been used from each new bottle of this medicine.