"In what clinical situation can a localised/specific
iron chelation be utalised Willie."

Well, Poyap, that is something to think about! I mean
something that is given systemically but can act more
locally where the inflammation is to inhibit the
availabillity of iron. I guess it is a problem of drug
design & delievery systems-a problem for the
pharmacologists

Good analagee,... but the 'country's innocent, citizens
may also be starved to death' because of the generalized
anemia, especially as you know if there are other medical
problems, especially cardio-respiratory conditions etc.

As I know innate immunity is the frontline line, mainly
nonspecific defence against invaders.

Probably, we could say, that this system protects from
further infection & also to suppress the growth of already
invading bugs. But not totally effective in completely
clearing the bugs.

Dendritic cells are also component of the innate immunty.
As I have mentioned several times before, OK-432 or killed
bacteria have been used to activate them to keep them more
alert than usual to effectively & quickly attack any bugs
& even cancer cells. It is said, that they have a certain
degree of specificity too. Hepcidin system is another
component of the innate immunity that tries to minimise
infection.

Broadly speaking, is it the innate immunity or the
adaptive (more specific & effective, but slower) immunity
we should utillize to control infection? That means
specific vaccines/vacination.

Any other views?

William

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