PFPC Daily - January 16, 2004

New Prozac Blues
Dutch study raises new concerns for some users

Time - Jan. 16, 2005

By SORA SONG

Adding to the concerns about antidepressant use, a Dutch report in
the Archives of Internal Medicine highlighted another problem with
the pills: abnormal bleeding.

Patients taking drugs that strongly inhibit reuptake of serotonin
— a neurotransmitter that aids both mood and blood clotting —
were at least twice as likely to be hospitalized for bleeding in the
brain, uterus and other sites than patients taking weaker drugs.
So-called SSRIs, including Prozac and Paxil, were among the strongest
drugs.

The risk is small, however, and most serious for patients already at
elevated risk for bleeding.

SOURCE:
http://tinyurl.com/67hxr