Hi Georgia!

Yes! It is nice to see they are moving along in all
the research now!

Hope you are feeling well!

Casey
--- Georgie B <Georgieb99@...> wrote:

> Thanks for this very interesting info. I had heard
> this theory for years but now it's been
> substantiated.
>
> Georgia Borland, an "Old Crohn"
>
>
> ----- Original Message -----
> From: Casey Smith
> To: OC CCFA yahoo group
> Sent: Saturday, May 31, 2008 9:54 AM
> Subject: [oc_ccfa] Scientists ID New Genetic
> Markers for Bowel Disease
>
>
> Scientists ID New Genetic Markers for Bowel
> Disease
>
> FRIDAY, April 4 (HealthDay News) -- Researchers
> have
> identified new genetic markers for Crohn's disease
> and
> ulcerative colitis in a study they say provides
> further evidence that people of Ashkenazi Jewish
> descent are more likely to develop the conditions.
>
> Up to 30 percent of people in the United States
> with
> inflammatory bowel disease (IBD) have a family
> history
> of the condition, and about 25 percent of those
> families have histories of both Crohn's and
> ulcerative
> colitis, according to background information in
> this
> multi-center American and Canadian study. People
> of
> Ashkenazi Jewish (eastern European) descent are at
> least twice as likely to develop a form of IBD and
> are
> more likely to have a family history of IBD.
>
> Crohn's is most frequently characterized by
> inflammation of the final section of the small
> bowel
> and parts of the colon, while ulcerative colitis
> involves inflammation of the internal lining of
> the
> rectum and colon.
>
> In this study, researchers looked for DNA
> variations
> called single nucleotide polymorphisms (SNPs) in
> 993
> families (244 of whom were Ashkenazi Jews) with
> Crohn's and ulcerative colitis.
>
> Among those of Ashkenazi Jewish descent, the
> researchers found evidence of genetic markers for
> familial Crohn's disease on previously identified
> areas of chromosomes 1 and 3. They also pinpointed
> a
> previously unidentified region of chromosome 13 in
> both Jewish and non-Jewish families with Crohn's.
>
> The researchers also identified areas on
> chromosomes 2
> and 19 that may be related to ulcerative colitis
> in
> both groups.
>
> The findings were published in the March issue of
> Genes and Immunity.
>
> Until now, no gene regions implicated in IBD were
> specific to Ashkenazi Jews, and there was no
> genetic
> evidence to explain why they were twice as likely
> to
> develop the disorder, said study senor author Dr.
> Steven R. Brant, a gastroenterologist at Johns
> Hopkins.
>
> "This increased risk for some Jewish people makes
> our
> study and results especially significant, since
> this
> is the first sample size of Jewish families, 244,
> that
> was large enough to identify novel gene regions
> for
> familial predisposition in this ethnic group,"
> Brant
> said in a prepared statement.
>
>
>
http://www2.healthtalk.com/go/crohns-disease/news/article?aid=1B741360-3048-8581\
-84B7EDC78BA645CA&utm_source=HTNL
>
> I thought this was interesting! I hope all of you
> are
> flare free!
>
> Hugs, Casey
>
>
>
>


Love, and Blessings,
Casey Smith


"Those who hope in the Lord will renew their strength. They will soar on wings
like eagles; they will run and not grow weary, they will walk and not be faint"
Isaiah 40:31