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Hi
I work in a lab and test warfarin levels (INRs) all the time...Hopefully I can be of some help here.
If Glen has been on 15mg of warfarin this whole time, then more time is not going to increase his level. It only takes 4-5 days for a change in dose to become effective. So I think Glen actually needs a small increase in dose, then INRs done every 3 days or so to see if it stabilises in the 2-2.5 range. Taking Clexane will help prevent any clots meantime, but doesn't affect the INR at all - it works an entirely different way. No one actually bleeds on warfarin unless their INR is about 8...unless they have liver disease or other bleeding tendencies anyway. So don't let too much time go by before getting the doc to agree to try another 2mg of warfarin.
Liz (wife of Mark - with AA3 on Carboplatin chemo, having failed everything else offered)
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