E-MOVE reports anual Meeting of the American Academy of
Neu held in Honolulu March 29-April 5 2003. Poster numbers, session
numbers, and pages are from Neurology 2003;60.

Continued efficacy and safety of subcutaneous injections of
apomorphine in the treatment of off episodes in Parkinson's disease
JH Sherry, PJ Guyton, B Van Lunen, PB Bottini S09.005 A81

Apomorphine injections continue to be effective for off period rescue
for at least 3 months, according to this study.

Sixty-two PD patients who had used apomorphine for at least 3 months
(average of 2 doses per day) were randomized to receive either
placebo or apomorphine, either at their standard dose or with an
additional 2 milligrams, administered during an off period.
Improvement in Webster Step-Seconds was seen by 7.5 minutes.
Improvement in UPDRS motor score was significantly better at both 10
and 20 minutes, with a return to baseline by 90 minutes.