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Post exposure prophylaxis for HIV in Medicos: Awareness and practice   Message List  
Reply | Forward Message #8686 of 9100 |
Re: HIV Transmission and Risk Factors: Some life saving facts!

Dear NetRUMians,
It seems that the topic is gaining momentum.

Disclaimer: I apologize before hand if my comments, explanations, remarks and discussion are felt offensive to anyone. I'm trying to be plain, simple and blunt in "fact" reporting!

@Anupama
@Meenal
@Nishant
It would be great if we can give our reasons for choosing the answers.

Instead of just giving answers I would rather like to discuss them let you all decide your scores.

Q2: When we talk of HIV transmission it basically depends on the duration of contact and surface area of at risk surface (when the amount of virus aka dose of infective material remains the same)
This is the reason direct blood inoculation like blood transfusion has 90+ transmission rate.
 So when we compare man to woman and woman to man transmission, it seems obvious that it is the fairer species which are at a greater risk for getting HIV infection. The surface area of vaginal mucosa (exposed surface) is way more than the corresponding area in man (glans). Also in case of woman the infective material aka semen remains in vagina for a longer duration than the brief exposure of glans to vaginal fluids during sex!
All this logic holds only if we see "per sexual encounter" rates!

Q3: Another important factor in the transmission of HIV is the exposed surface itself. So intact keratinized skin is more resistant to HIV than a traumatized mucosa.
Now if we think closely into the physical aspect of different types of "Sex" (aka "the ACT"), we may realize that more the trauma (in the "heat") more will be the chances is HIV transmission.
And Bingo we get the answer: Anal canal is not naturally designed for being a receptacle for "member" but as an outlet for the residue of digestive process. Add to it lack of lubrication and we end up in having more trauma to both parties' exposed mucosa. This equates to higher risk of HIV transmission than both oral and vaginal Sex.

Q4: Again the more traumatized the exposed surface is, the higher is the risk for HIV infection.
During menstruation the endometrium is sloughed off making it more susceptible for HIV transmission!

Q5: HIV is a rather delicate virus (It seems a stark contrast when compared to its capabilities). Until now there has been no known report of HIV transmission by:
1. Mosquito bite
2. Using same toilet seat
3. "Social" kiss aka "peck-on-cheeks"
HIV fails to survive in  these "harsh" environments!

Q6: Now this one is rather interesting.
In deep kissing aka "French" kiss there is prolonged contact of infective material (saliva- Yes, HIV has been detected in saliva!) and oral mucosa. Theoretically HIV can penetrate any mucosa (which is
nonkeratinized). Also if there are any cuts aka breeches in the mucosa HIV can be transmitted. Though there never has been any reported case of HIV transmission by a French Kiss! :)
For Oral Sex similar logic holds true. Trauma to exposed mucosa + infective material (semen) = HIV getting one more victim!
HIV is transmitted via breast milk!


Waiting to hear your comments.
Sincerely,
Navneet


Dr Navneet Kumar,

MBBS,

Government Medical College,

Nagpur,

India
 
 


--- In netrum@yahoogroups.com, anupama sukhlecha <anupama_acad@...> wrote:
>
> Dear Navneet,
>  Except for the first answer, my answers are similar to Nishant's. Probably it is 1-a
>  
> Anupama
>
> --- On Tue, 3/11/09, nishant singh nishantsingh2001@... wrote:
>
>
> From: nishant singh nishantsingh2001@...
> Subject: Re: [netrum] HIV Transmission and Risk Factors: Some life saving facts!
> To: netrum@yahoogroups.com
> Date: Tuesday, 3 November, 2009, 7:16 PM
>
>
>  
>
>
>
>
>
>
>
>
> 2 b
> 3.c
> 4. c
> 5. d
> 6. d
>
>
> hope i got all of em correct!!
>
>
> Dr Nishant Singh
> JR 2 @ GMC Amritsar
> --- On Tue, 3/11/09, Neet <navneet_malviya@ yahoo.com> wrote:
>
>
> From: Neet <navneet_malviya@ yahoo.com>
> Subject: [netrum] HIV Transmission and Risk Factors: Some life saving facts!
> To: netrum@yahoogroups. com
> Date: Tuesday, 3 November, 2009, 12:11 AM
>
>
>  
>
> Dear NetRUMians,
>
> If you think you know all about how we can get HIV infection, just go through the following questions and post your answers.
> We'll concentrate on some important "fine print" facts about transmission and risk factors for HIV.
>
> (ii) Transmission of HIV:
>
>
>      2. During sexual contact HIV infection is more frequently transmitted from:
>        a.      Man to woman.
>         b.     Woman to man.
>
>         c.      Both are equally infective.
>         d.     Nocorrelation.
>       e.   Don't know.
> 3.  Sexual act by which route carries highest risk for HIV transmission:
>       a.  Vaginal
>       b.  Oral
>       c.  Anal
>      d.  All are at equal risk.
>      e.  Don't know.
>
> 4. During which period of menstrual cycle is a woman at a higher risk for HIV infection after coitus:
>    a. Before menstruation.
>    b. After menstruation.
>    c. During menstruation.
>    d. Equal risk during entire cycle.
>    e. Don't know.
>
> 5. HIV can not be transmitted from an HIV positive person by:
>    a. Mosquito bite.
>    b. Using the same toilet seat.
>    c. Social kiss.
>    d. All of the above.
>    e. Don't know.
>
> 6. HIV infection may be transmitted by:
>    a. Deep kissing.
>    b. Oral Sex.
>    c. Breast feeding.
>    d. All of the above.
>    e. Don't know.
>
> Lets see how much we know?
> In hope of lessening our chances of getting HIV infection by using the power of knowledge,
>
> Navneet
>
> -- In netrum@yahoogroups. com, "Neet" <navneet_malviya@ ...> wrote:>
> >
> > Dear NetRUmians,
> >
> >
> > @ Dr Meenal: Bingo! You scored the opening point!
> >
> >
> >
> >
> >
> > As Dr Meenal as hascorrectly pointed towards the main hurdle in the
> > triumph of HIV vaccine which is thehigh mutability of HIV.
> >
> > Recently there were reportsof the results of a Phase III trial of ALVAC,
> > a recombinant canarypox vector vaccine and AIDSVAX, arecombinant
> > glycoprotein 120 subunit vaccine which was stated to showpositive
> > results against HIV-1:
> > http://www.guardian .co.uk/world/ 2009/sep/ 24/hiv-infection -vaccine- aids-b\
> > reakthrough
> > <http://www.guardian .co.uk/world/ 2009/sep/ 24/hiv-infection -vaccine- aids-\
> > breakthrough>
> >
> > But as rosy as it may seemsif one goes through the original article:
> > http://content. nejm.org/ cgi/content/ full/NEJMoa09084 92
> > <http://content. nejm.org/ cgi/content/ full/NEJMoa09084 92>
> >
> > we can see the results are a bit hazy.
> >
> > The modest effect shown bythis trial was based on a handful of cases- 23
> > to be exact although it was equivalent to being statistically
> > significant- p= 0.04! Strangely "Vaccinationdid not affect the
> > degree of viremia or the CD4+ T-cell count insubjects in whom HIV-1
> > infection was subsequently diagnosed"!! !??!!!
> >
> >
> >
> >
> >
> >
> >
> >
> > Do give your valuable comments on this.
> >
> > In hope of a miracle against HIV,
> >
> >
> >
> >
> > Navneet
> >
> >
> >
> >
> >
> >
> >
> >
> > --- In netrum@yahoogroups. com <mailto:netrum@ yahoogroups. com ,
> > "drmeenal.tiwari04" drmeenal.tiwari04@ wrote:
> > >
> > > Hello everyone,
> > >
> > > The cause of lack in development of a potential vaccine against AIDS
> > is that HIV is a highly mutable virus...this is what I can say from my
> > knowledge about AIDS
> > > lets see what others have to say ..!!
> > >
> >
>
>
>
> Now, send attachments up to 25MB with Yahoo! India Mail. Learn how.
>
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> Keep up with people you care about with Yahoo! India Mail. Learn how. http://in.overview.mail.yahoo.com/connectmore
>


Thu Nov 5, 2009 2:59 am

navneet_malviya
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Message #8686 of 9100 |
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Let's take out a minute and pray to the Almighty to grant strength to Vijay Sir and his family and may Panacea shower her blessings on Dada ji! Dear Members, ...
Neet
navneet_malviya
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Nov 1, 2009
3:49 am

Hello everyone, The cause of lack in development of a potential vaccine against AIDS is that HIV is a highly mutable virus...this is what I can say from my...
drmeenal.tiwari04
drmeenal.tiw...
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Nov 1, 2009
5:29 pm

Dear NetRUmians, @ Dr Meenal: Bingo! You scored the opening point! As Dr Meenal as hascorrectly pointed towards the main hurdle in the triumph of HIV vaccine...
Neet
navneet_malviya
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Nov 2, 2009
2:34 am

Hello Navneet,   You have selected a wonderful topic which is still in the grey area. It is also helpful for the exam going PG students like me, and a great...
swapnil jaiswal
drswapniljai...
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Nov 2, 2009
6:28 pm

Dear NetRUMians, @ Dr Swapnil: You pinned the facts correctly. There are in fact a lot of gray areas which one can come across when we go through the complete...
Neet
navneet_malviya
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Nov 2, 2009
7:28 pm

Dear NetRUMians, If you think you know all about how we can get HIV infection, just go through the following questions and post your answers. We'll concentrate...
Neet
navneet_malviya
Offline Send Email
Nov 2, 2009
6:42 pm

2 b3.c4. c5. d6. d hope i got all of em correct!! Dr Nishant SinghJR 2 @ GMC Amritsar--- On Tue, 3/11/09, Neet <navneet_malviya@...> wrote: From: Neet...
nishant singh
nishantsingh...
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Nov 3, 2009
1:46 pm

Dear Navneet,  Except for the first answer, my answers are similar to Nishant's. Probably it is 1-a   Anupama ... From: nishant singh...
anupama sukhlecha
anupama_acad
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Nov 4, 2009
3:48 am

Dear NetRUMians, It seems that the topic is gaining momentum. Disclaimer: I apologize before hand if my comments, explanations, remarks and discussion are felt...
Neet
navneet_malviya
Offline Send Email
Nov 5, 2009
3:04 am

\Dear Navneetmy answers were there coz of the same reasonings..anyways if the 2nd quest had an option of " man to man" then the correct ans wud`ve been this...
nishant singh
nishantsingh...
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Nov 5, 2009
6:21 pm

Dear NetRUMains, @ Nishant I completely approve your option but we must keep in mind its secondarily to the fact that "man to man" transmission would have a ...
Neet
navneet_malviya
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Nov 5, 2009
6:45 pm

Dear NetRUMians, Apologies for the unexpected delay in this post! So with the discussion getting hot, lets see how we fare on these some less known facts on...
Neet
navneet_malviya
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Nov 8, 2009
11:24 pm

hello Neet you did not post your replies to q .7,8and 9. I am waiting to get them.  kunda ... From: Neet <navneet_malviya@...> Subject: [netrum]...
kunda gharpure
gharpurekunda
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Nov 12, 2009
5:39 am

Dear Navneet, My answers are 7.   d 8.   c 9.   a   May we know the right answers?   Anupama ... From: kunda gharpure <gharpurekunda@...> ...
anupama sukhlecha
anupama_acad
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Nov 12, 2009
9:11 am

Dear Navneet, These are my answers for the three questions given, 7. d 8. c 9. b Thanks Samson....
Samson George
sampg762000
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Nov 13, 2009
6:26 am

Dear NetRUMians, Apologies for the delay in my post. I had been busy with my USMLE stuff. Result: A good news to share- I cleared my USMLE Step 3 Examinations!...
Neet
navneet_malviya
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Nov 14, 2009
5:29 pm

Congrats Navneet for clearing USMLE!   Anupama ... From: Neet <navneet_malviya@...> Subject: [netrum] Re: Continued: HIV Transmission and Risk Factors:...
anupama sukhlecha
anupama_acad
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Nov 15, 2009
1:44 am

Dear NetRUMians, Thanks a ton for all of your best wishes! Hope the discussion stirred our minds and relieved of some of our doubts regarding HIV. [#-o] This...
Neet
navneet_malviya
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Nov 18, 2009
1:25 am

Dear NetRUMians, All the MCQs which I will be posting under this discussion are all covered under Intellectual Property Rights. They have been painstakingly ...
Neet
navneet_malviya
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Nov 5, 2009
8:27 am
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