Hi, all members and thanks to Dr. Mira mem  to invite and encourage me for participation in discussion.

 

Discussion topic is ethical issue in medicine development

 

Points to be considered:

 

- Most of the drugs which are banned at worldwide are available in india.and other developing countries and use frequently by consumers.

 

- Many multinational companies coming in india

because human volunteers are easily available(most of coming for money) in developing countries.so cost for production of new drugs is very much reduced than in developed countries.

 

- In developing countries most of the drugs (including schedule X) given as OTC by pharmacist. and sometimes serious ADR developed due to this.

 

- Animals are killed for testing of well known effects like contraction of rat colon and gineapig ileum by acetylcholine.

 

Most important factor is no any action taken by regulatory authority.According to my views following actions should be taken.

 

- There should be some active regulatory authority which prevents production and utilisation of these banned drugs.

 

- For conducting clinical trial strict ethical rules should be followed.

 

- There should be penalty to pharmacist for giving as well as consumer for taking schedule drugs as OTC. Regulatory authority should take action to production of those branded drugs which cause serious ADR.

 

- Animals should be killed only for new research and at places where appropiate facility available for testing of all organs of killed animal. For students few months posting should be given in pharmaceutical industry for animal experiments.

                                                           Akash Patel

                                                           Resident in Pharmacology

                                                           B. J. Medical College

                                                           Ahmedabad