RE: [nathanfaustmantrials] Re: This is a joke, right?
OK, so maybe this is a cheesy analogy, but this debate seems to be equivalent to some one saying, "I have a problem, I need to move 10,000 people every day from New York to Los Angeles." One person says "OK, let's build some airplanes and fly them there. " The next guys says, "No, I don't know how to build an airplane. Let's just walk."
Subject: [nathanfaustmantrials] Re: This is a joke, right?
I, for one, couldn't disagree more. The human trial, even on just TEN people would still require multiple blood tests, perhaps even several a day while they are figuring out dosage and frequency. I double-checked my data, and doing the blood tests by hand, just ONE test, takes a day and a half! The automation process makes it take minutes. We don't want a half-*&#ed job here. We want it thorough, and right. The money won't roll in, because this is a phase 1 trial. We don't want pharmaceutical money, because they have been known to squelch cure work because it's more profitable for them and their stockholders to maintain sick people instead of cure them.
Dr. Faustman HAS been doing work, validating that the same defect that exists in the NOD mice does also exist in humans. There's also other labs out there that continue to produce supporting data. Check out the Bike the Miles for Human Trials website for some more details about the research. They really have a great site, putting it in layman's terms, and demonstrate why we are where we are, very well. They talk about some possible reasons other cures in mice have failed in human trials (and how THIS one is different), and other labs with supporting data. Specifically, I found these links very helpful:
Seriously, we ALL understand feeling frustrated. Every time I have to calculate and inject a shot into my daughter's tender skin, every clinic visit I have to attend, every carb I have to count, every sick day I have to worry, I PRAY for the cure to come, and to come now.
However, I want the REAL and PERMANENT cure to come, not a false hope. I want them to do this right, and if that requires some patience on my part, then I will do that.
There are never any guarantees with discovery work such as this. We all just have to have trust in the process they are doing to get us to the cure. Having met Dr. Faustman, and discussed all of this at length with her, I completely trust her. Let's channel all our frustrated energy into helping this move forward.
Stacy Lavery Team Maryland Captain, Join Lee Now Campaign Moderator, Nathan/Faustman Trials Yahoo Group
--- In nathanfaustmantrials@yahoogroups.com, "stilltypeone" <stilltypeone@...> wrote: > > Bernard, what would happen if the trials began without the > equipment, and say 10 people were successfully treated? Then the > $$$$$ would rush to MGH. The theory would have been proven. > Again, I think the cart is before the horse on this. > Prove that BCG can successfully "cure" type I diabetes, then work > on "automating the process". > What happens if the automation process is completed, and the > treatment(s) are unsuccessful? Millions or dollars and more > importantly the efforts of thousands will have been wasted. > > > > > > > > > > > > > --- In nathanfaustmantrials@yahoogroups.com, "Bernard Farrell" > <bernard.farrell@> wrote: > > > > I know I'd love it all to be available now. But I also know some of > > what it takes to work with the FDA and others on new stuff. So I'm > > accepting this will be a long process. And I'll also bet there are > > obstacles coming we can't even see right now, so I expect some > future > > frustrations as well. > > > > I figure the biggest way I can make a difference is by raising > funds > > to support the research. What would happen if the MGH group > received > > $100 million in support money? I bet they'd start to make HUGE > progress. > > > > So...why not just pull out those credit cards and donate to the > > Iacocca Foundation (http://www.iacoccafoundation.org)? Last > weekend we > > shook some cans at the transfer station for a few hours and raised > > nearly $100, it all adds to the forward momentum! > > > > Bernard > > > > --------------------------------------------------------- > > Help me to cure Type 1 diabetes > > http://bernardfarrell.com/ride.html > > >
It's not negativity to question the process, the project plan, and where the money is going. It's smart business, particularly if some of us are contributing a...
OK, so maybe this is a cheesy analogy, but this debate seems to be equivalent to some one saying, "I have a problem, I need to move 10,000 people every day...
That's not the analogy. What if we did not know if LA existed? Wouldn't it make sense to send a couple people on foot first before building the plane? I...
THANK YOU LARA!!!!!!!!!!!! ... before ... be ... Did ... before ... move ... next ... just ... even ... I ... take ... thorough, ... been ... defect ... have ...
The project timeline has not been extended...it has always been estimated at 3 years costing approximately $11 million. The Iacocca Foundation and MGH publicly...
Thanks, Sue. I believe different dates were mentioned early in the fundraising process. I realize nothing can start until the researchers receive the grants. ...
I understand everybody is upset with the 2008 start date. Yes, it stinks and when I think about it I do get depressed. I have type 1 for 19 years and am just...
Well said, I agree 100%.Thank you. From: "imcimc1" <imcimc1@...> Reply-To: nathanfaustmantrials@yahoogroups.com To: nathanfaustmantrials@yahoogroups.com...
To be honest, I am 31 years old, have had Type I since the age of 1 and I do not believe there would be a cure in my life time. Ever since I could remember,...
In reading several postings in this group, it has become clear to me that many people here know a lot about Faustman's research, there are many gaps in the...
Reposting a message: This message was originally posted by Sue Root yesterday, and approved last night, but somehow was lost. Here it is again: Joshua, Here...
Joshua, Here is some additional information for you: Most people at this forum are aware that the NOD mouse is the animal model scientists routinely use to...
I have a good friend who works in cancer research and feels Dr. Faustman is the only one "on target." She feels that Dr. Trucco's work with dendritic cells is...
Joshua, I just received several emails from Dr. Trucco and Dr. Giannoukakis. They have yet to begin Phase I trials. Best estimate is safety trials will not...
This displays an important point about the use of BCG in the Nathan/Faustman trial - there won't need to be any safety trials since it's been around forever,...
Stacy, by definition Dr. Faustman's work will need to go through "Phase I" trials. Here are the definitions. Phase I: Researchers test a new drug or treatment...
... How right you are. I remember reading about several studies involving BCG and type-1 diabetes. Some looked at type-1 diabetes rates amoung people who had...
... Dr. Faustman showed regeneration of islet cells with and without using spleen cell transplants. The significance of her research demonstrated that those...
Sue, any idea what Dr. Faustman proposes to use as the second compound to make the "cure" permanent? ... using ... demonstrated ... times ... to no ... using ...
From what I understand, they know what to target and the effect they need to produce. I believe they plan to investigate and use a generic readily available...
Isn't there something called "toxicity trials" that can be avoided? Forgive me, though I have tried to educate myself as much as possible, I'm still learning...