I have a idea which I don't know if it's viable. Your knowledge
about chemistry, could help me.
I'm thinking to buy a preparing for 1 month supply = MCT Oil (950
cm3) + Fish Oil (250 cm3) + Primrose Oil (250 cm3 - I'm not
convinced about Borage Oil because even one part per million of the
toxin amabiline may prove harmful long term).
[The amabiline is only in the leaves and flowers, not the seeds from which the
oil is pressed. It is of so little concern that there is not a single PubMed
abstract about amabiline toxicity from borage oil. In fact, I could find no peer
reviewed reference about the amabiline content of borage oil. In addition, there
is hepatotoxicity in many, many of the things we all eat. That is why Kitty and
I take lots of N-acetyl-cysteine, silymarin, alpha lipoic acid to prevent any
liver damage. However evening primrose oil is the GLA oil that has been used in
most of the studies, and in may be slightly better apart from any amabiline
considerations. --Paul]
Is it possible to make an oil, emulsified with large amounts of fat
and water soluble nutrients, plus minerals without any problem (I
have people that can makes me it, but they're not so sure)
[Let's first clarify the meaning of "emulsion". From the Meriam-Webster online
encyclopedia:
"Mixture of two or more liquids in which one is dispersed in the other as
microscopic or ultramicroscopic droplets (see colloid). Emulsions are stabilized
by agents (emulsifiers) that form films at the droplets' surface (e.g., for soap
or detergent molecules) or impart mechanical stability (e.g., for colloidal
carbon, bentonite clay, proteins, or carbohydrate polymers). Less stable
emulsions separate spontaneously into two liquid layers; more stable ones can be
destroyed by inactivating the emulsifier, by freezing, or by heating.
Polymerization reactions are often carried out in emulsions. Many familiar and
industrial products are oil-in-water (o/w) or water-in-oil (w/o) emulsions: milk
(o/w), butter (w/o), latex paints (o/w), floor and glass waxes (o/w), and many
cosmetic and personal-care preparations and medications (either type)."
Thus, it appears that such a scheme would work for vitamins if done properly.
However, the digestive system will quite naturally inactivate the emulsion,
separate the nutrients into their oil and water soluble components and digest
them in the standard way. Therefore, I don't think that you would get any
enhanced absorption.
A better way might be to micellize the water soluble nutrients so that they
would be absorbed within the fat micelles and avoid the saturable absorption
kinetics of the intestinal cells. This has been done before, but it is not a
simple operation. For a simple definition of "micelle" see:
http://en.wikipedia.org/wiki/Micelle --Paul]
(Fat-soluble: Vitamin E, Tocotrienols from Annatto beans,
[Annatto (also called achiote and anatta) is a food colorant and flavoring which
we also use for a great meat/fish dish cooking flavor. While it is true that
Annatto beans contain tocotrienols and are used as the source by some
manufacturers, not all tocotrienols are in it. It contains 90% delta and 10%
beta form. Palm oil is the only source that contains all four forms. --Paul]
Co-Q10, Zeaxanthin, Alpha Lipoic Acid, Vitamin A and Vitamin D)
(Water Soluble: The rest: Acetil-L-Carnitine, Choline, CDP-Choline,
N-Acetil-L-Cysteine, absolutely every member of B Family (including
12 g / day of B5 for some acne I'm still suffering), Vitamin C,
Hesperidin, Quercitin, Resveratrol, Rutin and Grapeseed Extract.)
(Minerals minerals like Zinc, Copper, Selenium, Molybdenum,
Vanadium, Magnesium, Boron, Manganese, Chromium, Iodine.)
May be it's better not mix the 3 oils together and add all these
nutrients just to the MCT Oil and mix the unsaturated fish and
primrose oils in other bottle. Saturated fats are very stable and
haven't problems to light exposure and oxidation like the
unsaturated ones. I'm not sure if it's good to add some artificial
antioxidants to preserve it better.
[I am not at all sure that MCT (medium chained triglycerides) oil will work for
what you want and it has little value on its own. Because MCT oil is not a long
chain, it is both not metabolized, but also not absorbed via the same processes
(as micelles) as are longer chain fats. Since it is these micelles that also
carry many of the fat soluble nutrients into the blood stream, the MCT may not
be a good carrier for fat soluble vitamins. Instead, I suggest that you use
extra virgin olive oil for your "carrier". With the high amounts of polyphenols
from the first cold pressing, this oil is very beneficial and very stable (it
effectively contains is own antioxidants). I see no problem mixing the
polyunsaturated fats and the fact soluble vitamins and nutrients with extra
virgin olive oil. Those vitamins and nutrients plus the polyphenols in the extra
virgin oil should be plenty of antioxidant power to keep it fresh. If you are
concerned, then add a little BHT which is a safe, powerful and beneficial
antioxidant for oils.
Extra virgin olive oil should also be used in both cooking and salads. --Paul]
My principal objective is to take everything in one step, achieve
the absorption of every nutrient and principally which have very
hard bioavailability like B12, B1, Chromium, Vanadium and Manganese
and avoid each antagonism existent (aspect which could make me
forget to me zinc and copper antagonism -and removes some copper-
and calcium vs. magnesium, when the doses are high -indeed I've
formulated 0,9 g of elemental Magnesium Aspartate daily in one of
the formulas I buy, and in the other hand 12 grams of Calcium
Pantotenate, equivalent to 1,2 g of elemental calcium-)
[I fully understand your goal. Everyone of us would like to accomplish these
things also. However the human digestive system is not at all cooperative in
this respect and there is no proven method to achieve such a goal. I would
suggest getting your compounding pharmacy to make you two preparations: one of
the oil soluble supplements in oil, and the other of the water soluble
supplements as mixed powders in capsules. --Paul]
I read at your diet you're taking additional Riboflavin. I've read,
no more 27 mg are absorbed, the rest is excreted.
http://www.pdrhealth.com/drug_info/nmdrugprofiles/nutsupdrugs/rib_0263.shtml
[Such statements as this are standard establishment propaganda for just about
every B-vitamin and many others (including vitamin C). However there are several
reasons to ignore such statements.
1) These tests were done with bolus (single oral dose) amounts on an empty
stomach.
2) The fact that a nutrient it excreted in the urine is proof that it has
entered the blood stream and has been available to the cells for a certain
length of time.
3) If nutrients are taken with food, then the absorption is slowed and more
likely to not saturate the intestinal transport processes.
4) If a dosage is distributed at 3 meals, then the slower, more gradual amount
absorbed will decrease the rate of metabolism and excretion, so that the average
blood levels (and availability to cells) will be higher.
5) After the intestinal transport process are saturated, a small percentage
continues to be absorbed by passive diffusion. (That is why over 1 mg of B12
will still give a reasonable amount of absorption for those who have lost the
ability to biochemically process it - ie they have no intrinsic factor.) --Paul]