Paul Wakfer wrote:

>A post on sci.life-extension of the abstract http://pmid.us/18294626
>was of great interest to me because of my fairly low testosterone -
>the result of having only one testicle since the occurrence of
>accidental torsion at age 31 - albeit without any major symptoms of
>low testosterone. The referenced paper is a review of thymic
>involutions particularly as affected and reversed by sex steroids >and,
>respectively, their elimination. Notably, I have been able to >maintain
>a high level of immunity into my 70s, possibly aided by my lower >level
>of testosterone reducing my rate of thymic involution.
>
>Since I was able to obtain the full paper, I replied to the posting >of
>the abstract with some elucidating quotes from the paper at the link:
>http://tinyurl.com/5nvuzl
>
>Any additional comments or questions should be posted to
>sci.life-extension since that is where the thread began.
>This note is merely for those people who may be interested, but don't
>regularly read sci.life-extension as I and Kitty do.

It seems that low T has it's own set of problems though:

Urology. 2006 Dec;68(6):1263-7.
Prevalence of prostate cancer among hypogonadal men
with prostate-specific antigen levels of
4.0 ng/mL or less.
Morgentaler A, Rhoden EL.
Division of Urology, Department of Surgery,
Beth Israel Deaconess Medical Center,
Harvard Medical School,
Boston, Massachusetts, USA.
amorgent@...

OBJECTIVES:
To determine the prevalence of prostate cancer in
hypogonadal men with a prostate-specific antigen (PSA)
level of 4.0 ng/mL or less.

METHODS:
A total of 345 consecutive hypogonadal men with a
PSA level of 4.0 ng/mL or less underwent evaluation
with digital rectal examination and prostate biopsy
before initiating a program of testosterone replacement
therapy. All men had low serum levels of total or
free testosterone, defined as less than 300 and 1.5 ng/dL,
respectively.

RESULTS:
Cancer was identified in 15.1%. The cancer detection
rate was 5.6%, 17.5%, 26.4%, and 36.4% for a PSA level
of 1.0 or less, 1.1 to 2.0, 2.1 to 3.0, and 3.1
to 4.0 ng/mL, respectively (P < 0.05). Cancer was
detected in 26 (30.2%) of 86 men with a PSA level of
2.0 to 4.0 ng/mL. Cancer was detected in 21% of men
with a testosterone level of 250 ng/dL or less compared
with 12% of men with a testosterone level greater
than 250 ng/dL (P = 0.04). Men with free testosterone
levels of 1.0 ng/dL or less had a cancer rate of
20% compared with 12% for men with greater values
(P = 0.04). The odds ratio of cancer detection
for men in the lowest tertile compared with the
highest tertile was 2.15 (95% confidence interval
1.01 to 4.55) for total testosterone and 2.26
(95% confidence interval 1.07 to 4.78) for
free testosterone.

CONCLUSIONS:
Prostate cancer was present in more than 1 of 7
hypogonadal men with PSA of 4.0 ng/mL or less.
An increased risk of prostate cancer was associated
with more severe reductions in
testosterone.

PMID: 17169647

[Note: This abstract was the subject of an initiating thread message posted on
sci.life-extension in December 2007 - http://tinyurl.com/6fsjry Google Groups
does not permit reply to messages beyond 60 days (to the hour!) - this one is
"over the limit". **Kitty]