Hi,
Kinetin is a suppressor of sexual development in plants. Suppression
of sexual development favors anti aging in most models that I am
aware of and as such it would seem likely to apply to all biological
systems including humans given other plant hormone research. Auxin
comes to mind as a complementary adjunct. "Lucidril"
Regards,
Peter Giles

[Note: Peter's use of the word "Lucidril" (a brand name for centrophenoxine)
relates to the connection between centrophenoxine, a compound of two
biochemicals - dimethylaminoethanol (DMAE) and parachlorophenoxyacetate (pCPA),
and "a variety of plant hormones called 'auxins'" to which pCPA is "similar"
according to http://www.smart-drugs.net/JamesSouth-centrophenoxine.htm --Paul]


--- In morelife@yahoogroups.com, "Paul Antonik Wakfer" <paul@...>
wrote:
>
> [Note: Kinetin, N(6)-furfuryladenine, is a cytokinin that is a
plant growth factor naturally found in plant extracts and even in
human urine - http://pmid.us/11112419. Animal in vitro studies have
shown it to have important effects on cellular differentiation and
apoptosis and, specifically, to be "a strong inhibitor of oxidative
and glycoxidative protein-damage" - http://pmid.us/11027621.
> Because such studies have also shown Kinetin to have anti-aging
effects in human cells, its effects on skin have been researched for
several years and it began appearing in skin care products a couple
of years ago (at least in Toronto that I and Kitty saw). It is a
chemical that some knowledgeable people have suggested may have human
life extension benefits - http://pmid.us/11708719 and therefore I
have been watching it for some time now.
>
> The following email exchange is being posted because it supplies the
> first mammalian ingestion information that I have heard, even if
entirely anecdotal. For those who may be concerned, the permission of
the other respondant was obtained before this posting. --Paul]
>
> Mark Patterson wrote on 8/7/2007:
> > Paul & Kitty,
> >
> > This is VERY preliminary and antecdotal, but oral consumption of
> > kinetin may be very important and you are the first I wanted to
tell.
>
> Hi Mark,
>
> I have known about kinetin and have been following it since at least
> 2000. I spoke to one of its chief researchers and promoters (SI
> Rattan) at Aubrey de Grey's initial Cambridge life extension
> conference in 2002. Unfortunately since that time all the major
> research on kinetin has been geared towards its cosmetic dermal use
> and none towards ingestion.
>
>
> > 2 70 ml doses of kinetin solution per day
> >
> > I add one dose to a liter of water (the solution I use to take my
> > supplements - also includes 15 g creatine plus an amino acid
mixture
> > glycine/L-arginine pyroglutamate/carnosine/taurine) and the second
> > does to a green tea mixture (green tea/grape juice/lemon
juice/fiber).
> >
> > Kinetin solution created by adding .4 g of kinetin to a liter of
> > clear vinegar. In the future I'll be dissolving the kinetin in
> > glacial acetic acid to achieve a more complete solution.
> >
> > I appear to be regaining my sight (nearsightedness) reducing the
> > need for glasses, I can now sprint faster than my 17 year old son,
> > my complexion seems to be improving.
> >
> > Wishful/positive thinking? Quite possibly. If so I hope the
> > benefits of a positive attitude continue because I like what I'm
> > experiencing.
>
> This all sounds very positive and may well be the result of the
kinetin.
> I have not sought to take it nor to make it available to others
> because it has not had even one testing of ingestion in mammals as
far
> as I know. IMO, without some such testing it is too risky to take at
> this time.
>
> If you know of any others who are ingesting kinetin then it would be
> very useful to compile such a list, and their anecdotal reports of
> effects. This would be better than the total lack of information
that
> is currently available in the scientific literature and would at
least
> show the general short term safety of the dosages being taken. As
the
> duration of ingestion time increases for these "guinea pigs", the
> longer term safety would also become apparent.
> What is really needed is a lifespan study in mice or rats of kinetin
> versus controls and CR.
>
> --Paul
>