Having problems with message search?
Athabasca, Alberta, Canada is also on for MMM 2005.
Since the Cures-not-wars.org (CNW) site was down for awhile, then
if you sent email to Dana Beal or CNW, and did not get a reply, or
sent in info for other cities for MMM 2005, and that info is not
listed in the compilation email below or on the basic city list here:
http://www.geocities.com/tents444/mmm2005map.htm
then please resubmit the email and city info to:
dana@..., cnw@...,
tents444@... and you can use the MMM contact form, too:
http://corporatism.tripod.com/webform.htm
----Forwarded email begins----
Dana Beal <dana@...> wrote:
Date: Sat, 5 Feb 2005 20:52:14 -0500
From: Dana Beal
Subject: ``GMM 2005 #7: CNW Down Since Jan 27--Re-Post if You Tried to
Join 122 Cities on the Global Marijuana March May 7, 2005!
Important: get your city on the list for the Global Marijuana March, May 7, 2005!So far we have confirmed 122 cities:AlbanyAlbuquerqueAshevilleAthensAtlantaAucklandBskersfieldBergenBerlinBirminghamBooneBoulderBristolBudapestBuenos AiresBurlingtonCapetownCheltenhamChicagoChicoChristchurchCincinnatiColorado SpringsColumbiaDarwinDes MoinesDetroitDoverDublinDunedinEast LansingEau ClaireEugeneFayettevilleFrankfurtFt. SmithGrass ValleyHachitaHalifaxHartfordHiloHoustonHullJerusalemKansas CityKristiansandLethbridgeLexingtonLondonLos AngelesLyonMadridMexico CityMinneapolisMissoulaMontrealMoscowNashvilleNewarkNew PaltzNew YorkNimbinOgdenOrlandoOsakaOsloOuluPaiaParisPeoriaPhiladelphiaPhoenixPortlandPortlandPotsdamPragueRaleighRapid CityRenoRichmondRoanokeRomeRosarioRostockSalemSan AntonioSan FranciscoSan MarcosSanta BarbaraSanta CruzSapporoSarasotaSavannahSpokaneStavangerStevens PointSt. LouisStockholmTallahasseeTampaTel AvivThunder BayToledoTokyoTorontoTraverse CityTromsoeTrondheimTucsonTupeloTurkuTwin OaksUpper LakeVancouverViennaVisaliaWaikikiWarsawWashington, D.C.Wilkes-BarreWilmingtonWinonaThere is also some international MMM networking going on at
this CannabisCulture.com message forum:http://www.cannabisculture.com/forums/postlist.php?Cat=&Board=current-------------------------
Million Marijuana March. Banners, posters, handbills,
flyers. From 2004 MMM. Use for 2005 MMM ideas! Adapt foryour needs! Due to software upgrade problemsonly the full-size images and full-size image downloadscurrently are working-- go here:http://www.vienna2004.org/mmm/viewer.php?albid=510&stage=2
or if problems go to the home page URL:
http://www.vienna2004.org/mmm
and then click on "mmm2004"and then "Banners Posters Handbills"
Many of the MMM 2004 banners, posters, flyers, and
handbills were converted from PDF files to the gif and jpg
images found here. The freeware Adobe Acrobat Reader and the
freeware IrfanView were used.
http://www.adobe.com/products/acrobat/readstep2.htmlhttp://www.irfanview.com - IrfanView is a free image editor
that is useful for adapting these flyers and banners for
your needs. Download the full-size gif images since they usefar fewer kilobytes compared to the 640x480 and 800x600 jpg
versions of the same image. JPG image files are mainly for
photos and images with lots of color gradation. GIF image
files are much better for flyers and banners. IrfanView can
easily edit, reduce, or enlarge gif and jpg images.
These flyer and banner images were found elsewhere in the
photo gallery, and by following links on the MMM 2004 city
list pages, report pages, image pages, etc.. Flyers and
banners for other MMM years can be found through the first
link below: MMM images:
http://www.corporatism.netfirms.com/mmmimages.htm
2004 city list:
http://www.corporatism.netfirms.com/mmm2004.htm
2004 reports:
http://www.corporatism.netfirms.com/mmm2004rep.htm*****!!!Global Marijuana March--May 7, 2005: Updates, Reports!!!*****From: hempembassy@...PRESSRELEASE.......Nimbin Hemp seeking solutions to police raids which waste precious resources.
SPEAKERS WITH SOLUTIONS ARE PARTICULAR WELCOME (INCLUDING NORMAN HARVEY'S!!!)
ON THURS.,THE 27th OF JANUARY AT 1 PM IN ALLSOP PARK .
The Nimbin Hemp Embassy is organising a protest rally and discussion against the new wave of police harrassment of Nimbin,our culture,our residents and our visitors.
"We are at the same point we always come too,and it would be great to break new ground.Speakers with solutions or suggestions for change are particularly welcome.
"In the UK,the police pressured politicians to reclassify cannabis recently which freed up the courts and their time for more important police work which actually made some impact.It also gained police new respect in their communities.
"Without support from police for change it is difficult,but surely they must be tired of this merry-go-round.
"Otherwise,it's just more of the same-more jails,alienation,disrespect and anger.Let's try something new."
Michael Balderstone
Chibo Mertineit
Nimbin Hempembassy
www.hempembassy.net
02/66891842a.h.02/66897525--------------From: NeedelR@...updated: www.cannabischassidis.blogspot.com. this one quotes your website, and links to it too.
--yoseph------From: iamm@...Federal Court of Canada, Docket: A-20-98
Michael Taylor, Appellant and Attorney General of Canada, Respondent and The Canadian Jewish Congress, Intervenor
Reasons for Judgment: Sexton J.A. January 27, 2000Concurred in by: Robertson J.A and Evans J.A.Background Facts.[5] On November 15, 1993, Whealy J. of the Ontario Court General Division was scheduled to preside over the criminal trial of Dudley Laws. When the courtroom session began, Whealy J. noted that he saw some people wearing hats in the courtroom. He ordered that either the hats be removed or that the people wearing them leave.[16] In its reasons, the Court of Appeal did not "consider it necessary to form a concluded view" on whether the exclusion of members of the public who wore head coverings "is in itself sufficient to constitute reversible error," in light of its decision to accept Mr. Laws" appeal on other grounds. Still, the Court of Appeal did hold that Whealy J. erred in "the exercise of his discretion" when he distinguished "between a requirement of a particular faith and a chosen religious practice," since "freedom of religion under the Charter surely extends beyond obligatory doctrine." The Court also held that Whealy J. erred "in suggesting that only certain communities are clearly within the purview of the Charter," adding that "no individuals or religious communities enjoy any less Charter protection than the major and recognizable religions." The Court concluded that "the trial judge erred in excluding certain members of the public from the courtroom," and that in so doing, he "may well have inadvertently created the impression of an insensitivity as to the rights of the minority groups."The "bad faith" exception to judicial immunity:[30] It has been suggested that there are limits to judicial immunity. For instance, in an extract from Halsbury's Laws of England, 33 the authors noted:Whenever protection of the exercise of judicial powers applies, it is so absolute that no allegation that the acts or words complained of were done or spoken mala fide, maliciously, corruptly, or without reasonable or probable cause suffices to found an action. The protection does not, however, extend to acts purely extra-judicial or alien to the judicial duty of the defendant [Š]
--------------------------------
Please forward widely! Million Marijuana March. MMM.
The MMM 2005 city links are always clickable at these mirrors below.
MMM world map with many more links. Frequently updated:
http://corporatism.tripod.com/mmm2005map.htm andhttp://www.corporatism.netfirms.com/mmm2005map.htm and
http://www.angelfire.com/rnb/y/mmm2005map.htm and
http://members.fortunecity.com/multi19/mmm2005map.htm
Click the region names in the left chart column to go to their city lists.
Click the "countries" link to go to the list of countries.Worldwide.
With less than 5% of the world's population
the USA has over 2.2 million of the world's9 million prisoners!:
http://corporatism.netfirms.com/rates.htm and
http://corporatism.netfirms.com/world.htm
MMM (Million Marijuana March).
City list and world map:
http://corporatism.netfirms.com/mmm2005map.htmYahoo Group:http://groups.yahoo.com/group/cannabisaction*************************BUSHWHACKED!!****************************Focus on Iran Causes Uneasehttp://www.truthout.org/docs_05/012305B.shtml
House Report Proposes Troop Withdrawal Plan
http://www.truthout.org/docs_05/012305D.shtml
Bush Pulls 'Neo-Cons' Out of the Shadows
http://www.truthout.org/docs_05/012305E.shtmlU.S. "Losing the War in Iraq," Knight Ridder Reportshttp://www.truthout.org/docs_05/012405X.shtmlVincent Jauvert | Secret History of a Reelectionhttp://www.truthout.org/docs_05/012405H.shtml
Scott Ritter | The Salvador Option
http://www.truthout.org/docs_05/012405D.shtmlWhen Is the Right Time for Troops to Pull Out?http://www.truthout.org/docs_05/012405B.shtml
Molly Ivins | Alternate Realityhttp://www.truthout.org/docs_05/012305F.shtmlFrom: cureworks@...In the mid 1990's a series of articles written by Gary Webb were
published in the San Jose Mercury News about why so much crack
appeared on the urban streets of America in the mid 1980's. It
contained answers to the question of how so many people, what seemed
like the best and brightest, were suddenly addicted to the deadly
drug.
"According to the San Jose Mercury News, (Webb's Report)
Nicaraguan Contras, run by the CIA, delivered tons of cut-rate
cocaine to a young Los Angeles drug dealer named "Freeway" Rick
Ross. Ross, a street-wise drug dealer of mythic reputation, turned
the cocaine into crack and supplied the Crips and Bloods street
gangs, which saturated the market with crack and used the profits to
arm themselves with automatic weapons. The Crips and Bloods
developed chapters throughout the west. Ross later moved to
Cincinnati and helped spread the crack epidemic across the country.
Cocaine was supplied to Ross by Oscar Danilo Blandon Reyes, former
leader of the guerrilla army named the Fuerza Democratica
Nicaraguense (Nicaraguan Democratic Force) or FDN. Blandon used the
millions of dollars paid to him by Ross to buy weapons and equipment
for his anticommunist army that unsuccessfully tried to overthrow
Nicaragua's Sandinista government in the 1980s. "It is one of the
most bizarre alliances in modern history: the union of a U.S.-backed
army attempting to overthrow a revolutionary socialist government
and Uzi-toting 'gangstas' of Compton and South Central Los Angeles,"
the Mercury News reported."
Gary Webb was the author of the articles explaining how crack took
over urban America so quickly. That's why I call him an American
hero because he brought the truth to the American people at great
cost to himself.
The case of the death of Gary Webb has all the ear marks of a
murder, not a suicide, with a government cover-up possibility. In
case you feel the language is too strong, check out what happened to
Webb, whose book, Dark Alliance : The CIA, the Contras, and the
Crack Cocaine Explosion, looks deep into Iran Contra. Webb's book
provides documentation that the U.S. government during the Reagan
years was responsible for the explosion of crack in the 1980's. He
said he had more information to reveal.
Gary Webb was a journalist. Something was done to verify the
material he presented. It's called the Iran Contra Affair.
Freeway Rick in Los Angeles, who is in jail for his role, has
admitted to coordinating the efforts.
"There are no poppy fields in Harlem," is a line from the movie
"New Jack City" that still is true.
The suicide story goes that Webb shot himself twice in the head
after leaving a note for the moving men. As a reporter, words were
important to him. If he was going to commit suicide he would not
have left a note to the moving men that read, "Please do not enter.
Call 911 and ask for an ambulance." People ask for 9/11 when they
are trying to live. If his determination to die was so great that
he shot himself twice in the head, he would have saved 9/11 a trip
and asked for the coroner to be sent.
I've witnessed the effects of crack since the 1980's and have
over the years lost many folks to the pandemic no matter what I did.
Elected and appointed officials refused to deal with the subject in
Harlem, treating it like they were treating AIDS. I now see, after
viewing the material of Al Sharpton meeting with mob folks over
drugs, who Harlem's leadership was meeting with. I was told it was
not their problem as they played another record on the radio or
asked for another donation.
Crack was introduced in a gentle way. It usually happened when a
person was over their head in an emotional situation, like the death
of a loved one, and was casually offered crack as a way not to feelall the pain in the moment. Or as a party favor shared by folks who
thought the host was their friend or family.
Most did not understand what it was the first time they hit it.
Within a few days, addiction would set in, another customer. Many
reported that the only time after the first few free hits they got
free crack again was when they were trying to quit.
The only folks I know who broke the addiction did so through the
Lord. The rest are hopelessly lost, still.
Here's some of the material available for your review.
From The Nation:
"Webb's tale is a sad one. He was on to something but botched part
of how he handled it. He then was blasted and ostracized. He was
wrong on some important details but he was, in a way, closer to the
truth than many of his establishment media critics who neglected the
story of the real CIA-contra-cocaine connection.
In 1998, a CIA inspector general's report acknowledged that the CIA
had indeed worked with suspected drugrunners while supporting the
contras. A Senator named John Kerry had investigated these links
years earlier, and the media had mostly ignored his findings. After
Webb published his articles, the media spent more time crushing Webb
than pursuing the full story.
It is only because of Webb's work--as flawed as it was--that the CIA
IG inquiry happened. So, then, it is only because of Webb that US
citizens have confirmation from the CIA that it partnered up with
suspected drug traffickers in the just-say-no years and that the
Reagan Administration, consumed with a desire to overthrow the
Sandinistas in Nicaragua, allied itself with drug thugs."
From the Portland Independent Media Center:
"A quick reiteration of the official obituary waffle is as follows:
reported first, a suicide with multiple wounds to the head, then a
suicide with a wound to the head, then there's a speculated shotgun
wound to the face, by Mike Ruppert, because of a verbal report,
given to Ruppert from the coroner's office implying that Webb's face
was beyond recognition , and finally 2 wounds to the head with a .38
caliber revolver.
Incidentally his gun was kept in the nightstand next to his bed. It
was his Dad's gun. Nice touch of detail here. But what does it tell
us? Maybe, Gary was concerned, because he had been the recipient of
death threats? Maybe that's the REAL reason he had a gun in a drawer
next to his bed. According to an informative and revealing
article /audio segment, on Alex Jone's Prison Planet website, Gary
did indeed have something to be very worried about: Ricky Ross, one
of Gary Webb's primary sources had spoken to Gary in the days before
his death. Gary told Ricky that he had seen men scaling down the
pipes outside his home and that they were obviously not burglars
but 'government people'. Gary also told Ricky that he had been
receiving death threats and was being regularly followed. It was
also mentioned that Gary was working on a new story concerning the
CIA and drug trafficking.
Moreover, why was there so much confusion about the method and
number of wounds? Was it that difficult to sort out? Or was
something else going-on? I really liked the potshot in the final
obituary about the feverish conspiracy theorists on the internet who
had been calling the coroner's office, demanding to know the number
of wounds Webb ACTUALLY sustained. Now trying to determine factual
details based on confused reports makes you a conspiracy theorist.
Move on folks, nothing to see here! "
The Media Awareness Project has listed an article from the San
Francisco Bay Guardian explaining the terror Webb was living with in
this interview.
"...Then the Mercury publicly disowned the story-without ever giving
Webb or readers a convincing reason why. The paper's editors had
encouraged Webb in his research, but in the firestorm that
followed "Dark Alliance"'s publication they retracted their support
for the series. After the controversy, the Merc, which is owned by
media giant Knight-Ridder, exiled Webb from its Sacramento bureau to
the police beat in Cupertino. Webb left the paper and expanded "Dark
Alliance" into a book of the same name.
Just published by Seven Stories, it reinforces Webb's investigations
with newly uncovered evidence. But the mainstream media are ignoring
this new evidence too: the Post, the New York Times, and the L.A.
Titnes have all ignored Webb's book-no reviews, no news stories, no
coverage at all.
But as Rep. Maxine Waters ( who wrote a strong introduction for the
book ) told me, "Gary Webb has uncovered one of the dirtiest little
secrets of the Reagan administration -that we, as a government,
introduced a drug to America's inner cities that is literally
killing thousands of kids, and that we did it purely for short-term
political gain in support of a cause that didn't deserve our support
in any way.
For reporting that, Webb lost his job. But the book provides
vindication." We interviewed Webb by telephone while he was in
Seattle promoting his book. Bay Guardian: Did you do much new
reporting and research for the book after the series ran?
Gary Webb: A lot of stuff came out after the series ran. We got
3,000 pages of new documents from the L.A. Sheriff's Department's
investigation that was just amazing. Probably 90 percent of the book
is new.
BG: What were your most interesting or unexpected new findings?
GW: Some of the most interesting is the stuff the Mercurys News
chickened out on and wouldn't run. What was going on in the DEA's
office in Costa Rica, where the U.S. drug agents were supposed to be
investigating drug crimes but were either looking the other way or,
as a customs investigation found, were trafficking drugs themselves.
This conspiracy went farther than the CIA. It was so liberating to
have the chance to lay out everything you have in context and
explain to people why it matters.
BG: How did you get the new information?
GW: FOIA requests, tips, and the CIA Inspector General's January
report. And anytime you do a big story people come out of the
woodwork, and we had a number of those --specifically this fellow
Enrique Miranda, who was an aide to drug lord Norwin Meneses.
BG: One of the main criticisms of the series was that you didn't
have a smoking gun. Do you think you have one now?
GW: When you're dealing with the CIA, you're lucky to find any
f*cking paper at all, much less a smoking gun. You're never going to
find a CIA memo that says, "Go sell crack in L.A." So you have to
gather as much evidence as you can, take a good hard look at what
you've got, and a legitimate conclusion can become very obvious.
BG: Why do you think the mainstream press --from your own paper to
the Washington Post, the L.A. Times, and the New York Times -- went
so far out of their way to discredit your series?
GW: Because it's a very dangerous story. It makes people think bad
things about their country and their government. Newspapers will let
you think bad things about a certain politician, but when you start
questioning the foundations of our democracy they say, "He's a
troublemaker, a zealot, a maniac."
BG: Were there any valid criticisms that you went back and
reconfirmed, or any holes that you subsequently filled?
GW: Sure, absolutely. I've said all along that some parts of that
series should have been explained more fully. It was accurate but
incomplete. What I tried to do with the book is show all the other
evidence that we couldn't get into the newspaper, or were actually
prohibited from writing for the newspaper. Initially it was a
problem of space, but in the end it was self-censorship on behalf of
Mercury News management.
BG: Do you think the decision was made in Knight-Ridder's super-
headquarters, or was it strictly Merc management?
GW: I don't know, but I do know Knight-Ridder has backed the
decision all the way. I think the thing that frightened them the
most about my story was that suddenly there was this whole
reactivation of activist black groups getting together and demanding
some political changes in Washington. And I think, honest to God,
that they were more scared by the Senate Intelligence Committee
hearings than anything, when hundreds of citizens actually showed up
to watch their government in action and started hooting at theantics they were witnessing. It scared the living hell out of them.
BG: So what happens next? Do you hope Congress finally moves to do a
full investigations?
GW: I think we may actually create enough pressure to force the
government to release the rest of the reports we've done on this.
The public has to get riled up, though, or the government won't do
anything. I've been told that the key 600-page report on this, the
one that contains the secret agreement between the Justice
Department and the CIA allowing the CIA not to report drug
trafficking, will never be released, will never be declassified. I
don't imagine the CIA will ever be very eager to let that one
loose."
Here's the final piece for why I believe Gary Webb's death was a
murder and a possible cover-up.
He died around December 9, 2004. I can't find the official report on
line.
The Sacramento County Coroner's Office website says:
"The Sacramento County Coroner's Office is mandated by the
California Government Code § 27491 et seq. to determine the
circumstances, manner, and cause of sudden or unexplained deaths in
Sacramento County....
When a death appears to be from natural causes, the cause of death
may be available after 11:00 a.m. the morning following the death.
However, when the death is the result of a homicide, suicide,
automobile accident, and in many natural deaths, the cause of death
will not be available for several weeks because the forensic
pathologist will order toxicology tests. This does not delay the
release of the body."
Yet, in the case of the death of Gary Webb the Associated Press
reported:
"Gary Webb, Reporter Who Linked CIA to Drug Sales, Dead at 49
The Associated Press Published: Dec 12, 2004
SACRAMENTO, Calif. (AP) - Gary Webb, a Pulitzer Prize-winning
investigative reporter who wrote a controversial series of stories
linking the CIA to crack cocaine trafficking in Los Angeles, has
died at age 49.
Webb was found Friday morning at his home in Sacramento County, dead
of an apparent suicide. Moving-company workers called authorities
after discovering a note posted on his front door that read, "Please
do not enter. Call 911 and ask for an ambulance."
Webb died of a gunshot wound to the head, according to the
Sacramento County coroner's office."
My question is if the tests are not in for weeks, why the rush to
say it was a suicide double gunshot wound to the head? I've been
trying to understand why he would leave a note telling the moving
men to call 9/11 and send an ambulance when he was determined enough
to shoot himself in the head twice.
Like any good reporter, I look at who benefits most when something
like this happens. Webb was about to get rich from his book. A
sitting congress person wrote the intro. He had just sold his house
so he was probably sitting on some cash. Even if he had nothing,
money was coming. He was an in demand speaker who finally was
stepping on stage to talk about his work. In other words, he was a
man with a purpose. Suicide makes no sense here. If he just spoke
about what was proven in Iran Contra, he had plenty of material to
work with. The flaw is not with the truth.
What information did Gary have about folks in the Reagan
administration and crack that was new? Where are they now?. Why
would anybody want to murder Gary Webb?
The inventor Bruce DePalma once wrote "Truth has a ring to it which
is unmistakable to those in search of it." The government story just
doesn't ring true to me. Does it ring true to you?****!!!IBOGAINE TREATMENT NOW $1500 IN HOLLAND--CALL SARA, 0113134-624-1770 !!!****From:digital@... Subject:Re: [Ibogaine] Patrick you're in another book
On Jan 22, 2005, at 1:24 AM, Vivienne Elanta wrote:
He cautions against drugs and then shows how all the coolest people are f***'d
up 24/7 and it's nearly a commercial for heroin. He's got you Patrick with
heroin, technology, the new edge and loads of good stuff, but ibogaine has a
one word mention in a sentence somewhere in the back.
Hullo. I neither wrote nor edited the book. I haven't read it yet. When I talk about drugs then yes, heroin is always mentioned. So is ibogaine, and usually other whitelight molecules such as LSD.
What hits paper is almost exclusively junk. Ibogaine is stripped out, and LSD hasn't landed a single time.
The demographic that appears interested in whitelight molecules are the entheogen crowd. The people who want to listen 'bout ibogaine, are a broader mix. But primarily it all amounts to: preaching to the choir.
Everybody else wants the dirT. Junkie war stories.
Luv the photograph of Richard Hell and Johnny Thunders!
Thanks. That right up there ^^^ is an excellent summary. You fill up a message with angst about pimpin' junk's mystique, and close with, "Richard Hell and Johnny Thunders!!!! They're soooooo fucked-up. How cooL! <SwooN>" The end.
And, of course, you purchased the book.
"I was so shocked, disgusted, offended and outraged ... I bought 5 copies."
PatrickFrom:slowone@... Subject:Re: [Ibogaine] Huge amount of ibogaine press
Thanks for pointing that out.
From a brief look into GDNF, it seems to have both brain and
stomach effects, plus there seems to be a linkage of low GDNF with
insufficient breathing. Here are some items:
From http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=600837
"Boucher et al. (2000) demonstrated that glial cell line-derived
neurotrophic factor (GDNF) both prevented and reversed sensory
abnormalities that developed in neuropathic pain models, without
affecting pain-related behavior in normal animals. GDNF reduced
ectopic discharges within sensory neurons after nerve injury.
Boucher et al. (2000) hypothesized that this may arise as a
consequence of reversal by GDNF of the injury-induced plasticity of
several sodium channel subunits, and argued that their findings
provide a rational basis for the use of GDNF as a therapeutic
treatment for neuropathic pain states."
"In rodents, GDNF stimulates an increase in midbrain dopamine
levels, protects dopamine neurons from some neurotoxins, and
maintains injured dopamine neurons. Gash et al. (1996) extended the
rodent studies to rhesus monkey by evaluating the effects of GDNF
injected intracerebrally into monkeys that had had the
symptomatology and pathophysiologic features of Parkinson disease
induced by MPTP. The recipients of GDNF displayed significant
improvements in 3 of the cardinal symptoms of parkinsonism:
bradykinesia, rigidity, and postural instability. "
"Experimental application of growth factors can alter the density
and distribution of axon branches; hence, growth factor release may
be one means by which target cells regulate the number of synaptic
connections they receive. Nguyen et al. (1998) generated several
lines of transgenic mice that overexpress GDNF under a muscle-
specific (myogenin; 159980) promoter. They found that
overexpression of GDNF by muscle greatly increased the number of
motor axons innervating neuromuscular junctions in neonatal mice.
The extent of hyperinnervation correlated with the amount of GDNF
expressed in 4 transgenic lines. Overexpression of GDNF by glia and
overexpression of NTF3 and neurotrophin-4 (NTF4; 162662) did not
cause hyperinnervation. During the period of greatesthyperinnervation (birth to 3 weeks postnatal), the Myo-GDNF mice
exhibited a tremor. At neonatal ages, the shaking was sufficiently
obvious that transgenic animals could be distinguished from their
littermates without error. The severity of the tremor waned as
multiple innervation diminished. Normal rodent neonates have a
tremor that is most obvious during the first few postnatal days and
gradually subsides over the next week. This tremor may be analogous
to 'jitteriness' in human neonates. Disappearance of tremor
corresponded to the loss of multiple innervation in each transgenic
line, as it did in wildtype animals. "
It looks like some people were administered GDNF directly, but
unlike the announcement, the result is not in the top Google hits.From a news announcement on the part of 6 doctors, web page dated
2002:
"Developed by Amgen Inc., GDNF is a natural growth factor for
dopamine neurons and is found in low levels in the adult human
brain. It is believed the destruction of these neurons in the mid-brain causes the symptoms of Parkinson?s disease; current FDA-
approved treatments improve the symptoms but do not alter the
underlying disease process. Laboratory studies have demonstrated
that GDNF both protects and promotes regeneration of injured
midbrain dopamine neurons, and thus may directly influence the
degenerative disease process.
"This new investigational treatment uses a version of the Medtronic
SynchroMed® Infusion System, a surgically implantable, programmable
pump developed by Medtronic Inc. and pre-clinically tested at UK.
The system will deliver GDNF directly into the patient?s brain.
This new therapeutic approach makes possible treatments with drugs
that cannot be used at present because they do not cross the blood
brain barrier."
http://www.mc.uky.edu/parkinsons/HTM/GDNF.htm
Here's another study which sounds the same but the authors are
different:
"Gill et al. (2003) delivered GDNF directly into the putamen of 5
Parkinson patients in a phase 1 safety trial. One catheter needed
to be repositioned and there were changes in the MRIs that
disappeared after lowering the concentration of GDNF. After 1 year,
there were no serious clinical side effects, a 39% improvement in
the off-medication motor subscore of the Unified Parkinson Disease
Rating Scale (UPDRS), and a 61% improvement in the activities of
daily living subscore. Medication-induced dyskinesias were reduced
by 64% and were not observed off medication during chronic GDNF
delivery. Positron emission tomography (PET) scans of [18F]dopamine
uptake showed a significant 28% increase in putamen dopamine
storage after 18 months, suggesting a direct effect of GDNF on
dopamine function."
GenAtlas has an interesting bunch of data:
http://www.dsi.univ-paris5.fr/genatlas/fiche.php?symbol=GDNF
Looking for possible ibogaine connections (there is much more,
including the DNA sequence):
"physiological period: fetal, pregnancy - developing gut, kidney,
mesenchyma, developing and regenerating peripheral nerves and
central nervous system, gut and kidney
"SUBCELLULAR LOCATION: extracellular
"basic FUNCTION:
- promoting survival and differentiation of subpopulations of
central and peripheral neurons including several groups;
stimulating Schwann cell migration via NCAM but independently of
RET
- playing an essential role in neural crest stem cell migration"
Brain cells allowed to change sounds familiar.
"cellular process: cell life, antiapoptosis
"text: neurogenesis,development and maintenance of intrahippocampal
circuitry and neuronal function and neuromuscular synapse"
I wonder if 'neuromuscular synapse' could have anything to do with
ibogaine's ataxic effect.
"signaling: signal transduction
"associated pathology:
- many neurodegenerative disorders
- gliomas
"susceptibility: susceptibility to Hirschsprung disease and to
phaeochromocytoma"
I wonder if people with these problems would react differently to
ibogaine. Perhaps it would be worth adding a question about this to
any data-gathering on takers of ibogaine.
Random info from other sites:
"Nonmetastatic testicular tumors were regularly formed in older
GDNF-overexpressing mice."
"This gene encodes a highly conserved neurotrophic factor. The
recombinant form of this protein was shown to promote the survival
and differentiation of dopaminergic neurons in culture, and was
able to prevent apoptosis of motor neurons induced by axotomy."
"Function: Neurotrophic factor that enhances survival and
morphological differentiation of dopaminergic neurons and increases
their high-affinity dopamine uptake."
"Disease: defects in gdnf may be a cause of hirschsprung disease
(hscr) [mim:142623]. In association with mutations of RET gene,
defects in GDNF may be involved in Hirschsprung's disease. This
genetic disorder of neural crest development is characterized bythe absence of intramural ganglion cells in the hindgut, often
resulting in intestinal obstruction.
"Disease: defects in gdnf are a cause of congenital central
hypoventilation syndrome (cchs) [mim:209880]; also known as
congenital failure of autonomic control or Ondine's curse. CCHS isa rare disorder characterized by abnormal control of respiration in
the absence of neuromuscular or lung disease, or an identifiable
brain stem lesion. A deficiency in autonomic control of respiration
results in inadequate or negligible ventilatory and arousal
responses to hypercapnia and hypoxemia"
"hypercapnia: [n] the presence of an abnormally high level of
carbon dioxide in the circulating blood"
[hypercapnia: not breathing enough]
"Hypoxemia, or reduced oxygen in the blood,"
"On the Aug 2004 Human genome, NCBI 35 version of the human genome:
8 genes relate directly or indirectly to GDNF"
"10 bioalma disease relationships for GDNF are shown
Disease Score Articles
hirschsprung disease 135.29 78
parkinson disease 83.87 171
neurodegenerative diseases 79.31 114
multiple endocrine neoplasia 63.44 31
amyotrophic lateral sclerosis 49.99 49
multiple endocrine neoplasia type 2a 40.92 26
nerve degeneration 31.33 36
other motor neuron diseases 25.89 2
thyroid carcinoma, familial medullary 23.94 5
multiple endocrine neoplasia type 2b 21.82 12 "
"10 bioalma chemical compound relationships for GDNF are shown
Compound Score Articles
tyrosine 69.02 247
heparan sulphate glycosaminoglycan 43.07 3
dopamine 38.88 120
mesencephalic dopamine 34.79 6
neurotoxin 6-hydroxydopamine 33.55 6
6-hydroxydopamine 33.07 27
glycosyl-phosphatidylinositol 29.39 9
ototoxin 24.97 2
rasagiline 24.79 3
phosphatidylinositide 22.84 5 "
There is lots more out there..
"The paper looks very solid," says Stanley Glick, a
neuropharmacologist at Albany Medical Center in New York, who has
studied ibogaine for many years. "They may indeed be on to a major
finding." However, both Glick and Ron point out that boosting GDNF
may be only one of several mechanisms by which ibogaine acts to
ease addiction.
A synthetic ibogaine compound, 18-methoxycoronaridine, which Glick
has shown can help addicts with fewer harmful side effects than
ibogaine, may also work by controlling GDNF levels. In preliminary
studies with cultured nerve cells, Ron's team found that 18-MC
also
raises GDNF levels.
I wonder what else may also raise GDNF levels, from antidepressants
to ayahuasca.
But the team is not pursuing the ibogaine approach. Instead, Ron
thinks it is time to narrow her focus. "Our idea now is to move
away from ibogaine and concentrate on GDNF," she says. Her teamplans to look for ways to stimulate GDNF without side effects.From:aktionman@... Subject:Re: [Ibogaine] patrik inna book!!!!!
Luv the photograph of Richard Hell and Johnny Thunders!
Thanks. That right up there ^^^ is an excellent summary. You fill up
a message with angst about pimpin' junk's mystique, and close with,
"Richard Hell and Johnny Thunders!!!! They're soooooo fucked-up. How
cooL! <SwooN>" The end.<
hey....load dijjial!!!!
junk's mystique.....havent thought abou that inna long time. having
spent the '70s in marin co. (north side of golden gate bridge) that
image grabbed me hard. what a place to get seduced by that sweetheart
w/fangs.
chasin' the dragon w/ garcia & others in the deadosphere.
nothin' heavy or evil........justtanother spice in the gumbo!!!
and always the shades......wear them night or day. like u board up thewindows to u'r soul. so no one will know.
sent shivers thru my spine just thinkin about it.p, l, an u!!!!!marcusFrom:Jeffgd1@... Subject:[Ibogaine] 10 weeks out
Hi Donna et al...
Well it has been a v-e-r-y slow but steady climb out of the 20 plus year opiate haze...the last ten years being strictly a methadone diet. At 45 years old my brain had a lot of reconnecting to do with itself and my body.I was on 50mgs when i did the ibo...looking back (ahh hindsight!) maybe i should have tried switching to a shorter acting opiate but didnt have a sympathetic Dr or want to go back to copping on the street
I went thru some very tough weeks post ibo i did a couple of "booster" doses about 2-3 weeks out and the nor-ibo (or wheteever it is) was flowing bigtime and gave me a great spirit (just as advertised) and then about 7 weeks post it simply dried up! I was still only about 75% back to'normal' and then it became much more difficult to focus on the positve.
Even now at 10 plus weeks my energy level is still low (as it was before ibo) and i am to put it simply, still, uncomfortable. Some nights i could swear i am feeling honest to god (minor) withdrawal pain though i cannot actually believe that i am at this point
I still try to focus on the fact that i am free now-to go and be wherever I want (as soon as the $ are thier) and that compared to 20 years 10 weeks aint but a drop in the bucket but it is hard.
I only chimed into the "ken" discussion cuz his posts seemed to hit home for me much more so than the full of positivity posts that i simply cant relate to right now. I am only glad for those that feel great and see the light so to speak but for me the road is still long.
Dont get me wrong I am a livemusiclovinglonghairedhippiefreak and all that-no doubt!but I am out of the old school grateful dead model no flowrpowerdaisyloving but hardpartyingbustyerballscraziness -toomuchofeverythingisjustenuff shut-upandpassthetray-pipe-joint type
To be fair I need to get out of the house more and excercise more and eat better and get into counseling and stop daydreaming so much and get moving and eat better and excercise and get back to work and get a hobby and move out of new york and meditate and join some kind of group and get back to my spiritual needs and eat more vegatables and see a chiroprator and do some volunteer work and get rolfed or something and focus on the just how far I have come but otherwise everything is fucking great!
hope that helps
Freak Freely!
JeffFrom:jasenhappy@... Subject:Re: [Ibogaine] 9 weeks in.
Hey guys,
Yes slow and steady,..I undersdtand what you mean Jeff.
The ship is still on course though the sails are not as full of wind.
It has been a 20 year plus opiate haze for me also. I am
39 now,..was on the Methadone since 15.
This is my ninth week,..my energy still is not right,..however
much better than before.
I was on 60mg when treatment started,..however 3 to 4 days
before doing the trearment I double and triple dosed.
I was scared shitless only to discover there was nothing
to fear.
The road for me is also long. I am still conected to the
all of it. I am very confused and not, if you understand
what I mean. My mind is still not firing properly.
I sometimes let out a big roar in frustration of the sickness.
My neighbours must think I am off my head.
I suppose I was,.. without thinking I was,.. the years previously.
Hey,..it's all good,..as long as I stay on track.
I own the track. The ship is pushing through ice,..the
freesailing will come soon.
I am still in love with everything,..I still see the man across
the road and see me,..the woman at the bustop and there I am again.
I was a lot like this before Iboga,..Iboga took me over the top
and it was/is wonderfull. Though I have come down some.
What a great and ful filling experience,..WOW
People are more attractred to me now,..woman are noticing me,..it feels great flirting. I have missed so much,..no regrets.
Even though I am still not quite right,..I am
still loving it,..this state I am now in.(No anesthetic)
Even 6 weeks ago when I was sicker,.I still felt great,..Free,
lighter.
I am more sociable,..I used to get invited to 10 things and
maybe go to 1,..now I get invited to 10 and go to at least 9.
I am free from opiates,..even the cig's however the cig's are
,...seem to be a different type of challenge. I fight the urge,,
maybe "urge" is not the right word,..I fight the habit of having
a cigg more than anythig else.
Broken the urge and habit of eating loads of sugar in all forms.
I am not as arrogant as before,..nor could I have seen my
arrogance before Iboga.
When people are talking to me now I don't drift off.
I am more steadfast,..grounded. People are more exciting.
I am feeling alot better than I was a month ago that's for sure.
Still have longer to go,..but then we are talking about Methadone.
I feel like I can become anything now,..good or bad,..it is a choice.
Some of what society labels "bad" can be good. Good and bad is relevent.
Hey,..maybe I'll be both,..the all of it. Mmmm.
love,.Jasen. (A big kiss for you Ken baby) (your big enough to handle it) :)
(All in good humor mate)From:HSLotsof@... Subject:[Ibogaine] Ken/was/Re: [Ibogaine] free
In a message dated 1/24/05 8:54:55 PM, chayco@... writes:
<< I suspect Preston is behind this......twiddling the levers like the great
OZ
he may well be.
Free me Preston.......Freeeeee meeeee.
Ah come on Ken,
Hang out. Dose regimens in treating methamphetamine dependence can be quite
varied. Everything from the normal 15mg/kg doses to prolonged regimens of
50mg to 150mg/day for a week or two or doses that are determined by the patient
on an as needed basis as a substitute for amphetamine. What has been seen in
some cases is that after a week or so the subject will lose interest in
amphetamine. Some issues of concern related to concurrent use and toxicity of
ibogaine and amphetamines and/or the issue of the subject remaining well hydrated
are serious. Lack of hydration may prove fatal. What is shown in both animal
model research and human observations is that ibogaine will raise brain levels
of amphetamine. The inverse may also be true. It is quite a crap shoot and
requires either knowledgeable drug users or knowledgeable doctors. Both in
combination would be best. Too bad we don't have an approved drug that could be
given to hundreds of methamphetamine users so we could begin to accumulate data.HowardFrom:HSLotsof@... Subject:Re: [Ibogaine] Ken/was/Re: [Ibogaine] free
In a message dated 1/25/05 12:43:18 AM, chayco@... writes:
<< My concern with methamphetamine abusers was the elevated heart rate and
entrenched psychotic behaviour.
It seems to me that ibogaine as an effective interrupter of opiate addiction
is a given, in most situations, but the effectiveness of ibogaine to
'interrupt' chronic methamphetamine abuse appears to not be as dramatic as
with opiates.
If there is a risk of ibogaine raising amphetamine levels in the brain, and
the 'self administered' is acting in an extremely psychotic and harmful
manner, what steps can the 'care giver' take immediately ? >>
Ibogaine is not as dramatic in interrupting methamphetamine dependence as it
is heroin dependence because there is no similar withdrawal signs seen with
methamphetamine as with opioids and thus the very dramatic elimination of opioid
withdrawal signs by ibogaine is absent with methamphetamine.
I anticipate that raised heart levels would be seen with active
methamphetamine use. If this is not the case then a cardiac disorder may exist. Cardiac
disorders are reason for the elimination of many patients from ibogainetherapy. Additionally, drug dependence, adverse drug effects and psychotic symptoms
are all distinct and may have to be dealt with in a distinct manner. If the
subject to be treated is exhibiting psychotic symptoms that may or may not be
associated with amphetamine use and/or cannot be depended on to cease
methamphetamine use long enough to be treated with ibogaine than I would only feel
comfortable treating the patient in a controlled environment. A hospital would
be great but, I guess that is non existent. Has an EKG and blood chemistry
including liver profile been obtained? Is the patent HCV or HIV positive? Any
other medical disorders? Does the subject want to be treated with ibogaine?
How much amphetamine and by what route is it administered? There arevariables here that could result in a fatal reaction.HowardFrom:sara119@... Subject:RE: [Ibogaine] cynicism and ibogaine
Iboga is offering spiritual insight and inspiration,
We have multi ego's or multi archetypes that are being Expressed. One day
you say "I'm not feeling myself today".
All the ego's like to be satisfied, the one who likes to be well
Without drugs and the one who can't feel well in a painful physical body.
the one ego likes to be detached and the other ego likes to be attached,
all in the same body.
You are talking to the same person but to what ego of that person?
( DH wrote few times), your monkey on the shoulder is one ego
And the music in you heart is another which always be there,which are you
listening to...?
Iboga can give you the insight how to observe your own ego's.
So it's ibogaine for limited withdrawals but also ibogaine for
Insight and inspiration.
Iboga will reduce big amount of bacteria ( parasites) that are living in
symbiotic relationship with our bodies, which is another story but make
iboga worth trying to reduce the chance of total invasion of your body,
And bring you closer to your original "you" when born, who is different to
the "you"
When invaded, also the bacteria is "asking to be satisfied", it will tell
Your brain and then you forget all the resolution. Which ego are you talking
to?
Anyways, I think it is more complexes then we can think of or more simple
then we can think of, but not yet realized.
Be well,
Sara-----Illegal Drug is Underground Addiction Treatment
Here and Now - MA,USA
... there. But there is a little-known drug called ibogaine that is traditionally used in Africa for certain tribal ceremonies. Taking ...http://here-now.org/shows/2005/02/20050204_2.aspTo join the Mindvox ibogaine list just send an email to ibogaine-subscribe@... if you please.Nothing more to it. You don't have to write anything in the subject or text area.-------------------------------------------------------------From: tents444@...http://www.corporatism.netfirms.com/mmmall.htm This page just created! Please forward and distribute widely.348 MMM cities worldwide since 1999!
MMM. All cities 1999 to date. Million Marijuana March. Global Cannabis Liberation in May. Worldwide since 1999. Cannabis events on the first Saturday in May, or that weekend, or thereabouts. Marches, meetings, rallies, raves, concerts, festivals, etc..******************************************************************************To get on the poster for 2005--update your contact details & add your city to this New List:[---snip---]
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A basic MMM 2005 city list with world map,
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