There are many variations of leukodystrophiess. It is thought to be a genetic ailment from a mom to her son. However, there is one leukodystrophy that only Auschwitz jews had.

I suspect it is a chemical poisoning that causes genetic harm: damage to the X chromosome, then the child has a birth defect that causes an abnormality in enzyme action. Long fatty chains are not broken down as they should be, causing a breakdown on the myelin covering of the nerves, and resultant inability to control muscles, etc. (this would be as with ALD)


The known leukodystrophies are listed below.

18q Syndrome with deficiency of myelin basic protein

Acute disseminated encephalomyeolitis (ADEM)

Acute Disseminated Leukoencephalitis

Acute Hemorrhagic Leukoencephalopathy

Adrenoleukodystrophy (ALD)

Adrenomyeloneuropathy (AMN)

Aicardi-Goutieres Syndrome

Alexander Disease

Adult-onset Autosomal Dominant Leukodystrophy (ADLD)

Autosomal Dominant Diffure Leukoencephalopathy with neuroaxonal spheroids

Autosomal Dominant late-onset leukoencephalopathy

Childhood Ataxia with diffuse CNS Hypomyelination (CACH or Vanishing White Matter Disease)

Canavan Disease

Cerebral Autosomal Dominant Arteropathy with Subcortical Infarcts and Leukoencephalopathy (CADASIL)

Cerebrtendinous Xanthomatosis (CTX)

Craniometaphysical dysplasia with leukoencephalopathy

Extensive Cerebral White Matter abnormality without clinical symptoms

Familial adult-onset leukodystrophy manifesting as cerebellar ataxia and dementia

Familial leukodystrophy with adult onset dementia and abnormal glycolipid storage

Globoid Cell Leukodystrophy (Krabbe Disease)

Hereditary adult onset leukodystrophy simulating chronic progressive multiple sclerosis

Lipomembranous osteodysplasia with leukodystrophy (Nasu Disease)

Metachromatic Leukodystrophy (MLD)

Megalencephalic leukodystrophy with subcortical cysts (MLC)

Neuroaxona