The European Commission has approved temsirolimus injection for the first-line treatment of advanced renal cell carcinoma. Japan's Ministry of Health, Labor,...
Higher than expected variation of creatine kinase (CK) activity within the population suggests that the upper reference limit should be increased, according to...
One-year results of the ACUITY trial, published in the December 5, 2007 issue of the Journal of the American Medical Association, show no significant...
An over-the-counter version of lovastatin (Mevacor) is again to be considered by the US FDA, with a joint meeting of the Nonprescription Drugs Advisory...
Using a multidrug regimen to prevent cardiovascular disease in high- risk individuals in low- and middle-income countries could avert 18 million deaths over 10...
A pair of epidemiologic studies published 24 years ago [1,2] suggesting steep drops in cardiovascular risk with vitamin-E supplementation, widely cited in...
The first clinical trials with Merck's new cholesteryl ester transfer protein (CETP) inhibitor, anacetrapib, have shown impressive effects on raising HDL and...
Researchers have gone back to the drawing board with the blockbuster drug imatinib and are working to eliminate its adverse effects. Sold in the United States...
Treatment with pramlintide improves several aspects of diabetes control and reduces weight in type 2 diabetic patients who are not achieving glycemic targets...
New data from two phase 3 trials with the oral anticoagulant rivaroxaban (Xarelto, Bayer/Johnson & Johnson) have been presented, suggesting it is more...
Post hoc analysis of data from the Stroke Prevention by Aggressive Reduction in Cholesterol Levels (SPARCL) trial looked at factors associated with the...
A new study suggests good physical functional health is associated with a reduced risk for stroke. The results, from the prospective European Prospective...
Switching the dose of one antihypertensive medication from morning to night helps restore circadian rhythm to blood pressure in patients with chronic kidney...
Average serum total-cholesterol levels in American adults over age 20 have fallen below 200 mg/dL, an analysis of 2005-2006 data from the National Health and...
The cholesterol ester transfer protein (CETP) TaqIB polymorphism is associated with the risk of sudden death in type 2 diabetic patients, according to French...
After five years of sluggish enrollment, the Surgical Treatment for Ischemic Heart Failure (STICH) has finally finished enrolling patients in its two-pronged...
Scientists from New York report the discovery of a previously unknown gene family that plays a key role in whether or not cells store fat, a discovery that...
The first study to apply a systematic genetic approach to Kawasaki disease (KD) has linked KD susceptibility to a functional single nucleotide polymorphism...
The UK Human Fertilization and Embryology Authority (HFEA) has granted the first license to a clinic to perform preimplantation genetic diagnosis of familial...
A new beta blocker, nebivolol (Bystolic, Forest/Mylan), has been approved by the US FDA for the treatment of hypertension. The drug is a selective beta 1...
The latest statistics compiled by the American Heart Association (AHA) show that deaths from cardiovascular disease in the US continue to decline, but there...
The latest statistics compiled by the American Heart Association (AHA) show that deaths from cardiovascular disease in the US continue to decline, but there...
An initial dose of 162-mg aspirin may be as effective as and perhaps safer than 325 mg for the acute treatment of ST-elevation MI (STEMI), a new study suggests...
For patients with type 2 diabetes beginning insulin therapy, metabolic control and quality of life seem to be similar with either flexible intensive insulin...
Results of a new prospective study have found an association between increasing levels of physical activity and a lower risk for vascular dementia, but not for...
The US Food and Drug Administration (FDA) has granted orphan drug designation to CDX-110 for the treatment of glioblastoma multiforme, ATryn for the treatment...
Women with a high number of years of fertility seem to be protected to some degree against developing gastric cancer, according to a report in the December...
Early data from a new drug that mimics the effects of the thyroid hormone has been shown to reduce LDL-cholesterol levels [1]. In addition to cutting LDL- and...
In a randomized study that explores a possible way to prevent unnecessary drug therapy aimed at "white-coat" hypertension, patients were more likely to reach...
Elevated levels of serum triglycerides and non¡Vhigh-density lipoprotein (HDL) have been associated with an increased risk of large artery atherosclerotic...
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