Wow.

Hal

--- In fqtoxicity@yahoogroups.com, Fqresearch@... wrote:
>
> I wish it was that easy Hal. What you have to is go through the reference
> list for the article (200+ references) and click on each one that has a
> link. If the link is broken you have to track it down and find the new URL.
> That is the easy part. But replacing it is not a cut and paste job, it is
> a BITCH to do. Wikipedia uses inline references, so it would look
> something like this when you go to make that kind of change:
>
>
> Ciprofloxacin is a [[broad-spectrum antibiotic]] that is active against
> both
> [[Gram-positive]] and [[Gram-negative]] bacteria. It functions by
> inhibiting [[DNA gyrase]], a type II [[topoisomerase]], and topoisomerase
> iv<ref>{{cite journal |author=Drlica K, Zhao X |title=DNA gyrase,
topoisomerase IV,
> and the 4-quinolones |journal=Microbiol Mol Biol Rev. |volume=61 |issue=3
> |pages=377â€"92 |year=1997 |month=Sep |pmid=9293187 |pmc=232616
> |url=http://mmbr.asm.org/cgi/pmidlookup?view=long&pmid=9293187
|day=01}}</ref>, which is
> an enzyme necessary to separate replicated DNA, thereby inhibiting cell
> division.
> The fluoroquinolones interfere with DNA replication by inhibiting an
> enzyme complex called DNA gyrase. This can also affect mammalian cell
> replication. In particular, some congeners of this drug family display high
activity
> not only against bacterial topoisomerases, but also against eukaryotic
> topoisomerases and are toxic to cultured mammalian cells and in vivo tumor
> models. Although the quinolone is highly toxic to mammalian cells in culture,
> its mechanism of cytotoxic action is not known. Quinolone induced DNA damage
> was first reported in 1986 (Hussy et al.)<ref>Hussy P, Maass G, Tümmler B,
> Grosse F, Schomburg U (June 1986). "Effect of 4-quinolones and novobiocin
> on calf thymus DNA polymerase alpha primase complex, topoisomerases I and
> II, and growth of mammalian lymphoblasts". Antimicrob. Agents Chemother. 29
> (6): 1073â€"8. PMID 3015015. PMC: 180502.
> _http://aac.asm.org/cgi/reprint/29/6/1073.pdf.</ref_
(http://aac.asm.org/cgi/reprint/29/6/1073.pdf.</ref) >.
>
> And you then have to find the bad reference within this text and then
> replace it. One space or letter out of order and you are screwed. The
> references are keyed in using <ref> the reference </ref> commands. Nowhere
near
> as easy as it looks. But the offer is certainly appreciated. Here is an
> example of what I am talking about, in the code I write to create the article
> a link looks like this:
>
> <ref>{{cite journal |author=Drlica K, Zhao X |title=DNA gyrase,
> topoisomerase IV, and the 4-quinolones |journal=Microbiol Mol Biol Rev.
|volume=61
> |issue=3 |pages=377â€"92 |year=1997 |month=Sep |pmid=9293187 |pmc=232616
> |url=http://mmbr.asm.org/cgi/pmidlookup?view=long&pmid=9293187
|day=01}}</ref>
>
> Where as in the reference list this is what YOU see:
>
> Drlica K, Zhao X (01 Sep 1997). "DNA gyrase, topoisomerase IV, and the
> 4-quinolones". Microbiol Mol Biol Rev. 61 (3): 377â€"92. PMID 9293187. PMC:
> 232616.
>
> So just finding the URL doesn't get it. You still have to format it and
> place it within the document where it belongs.
>
> capt' dave
>
> In a message dated 7/2/2009 11:45:53 P.M. Pacific Daylight Time,
> reallynolie@... writes:
> If I can help send me some work. Not sure what it takes other than going
> through the FDA site and matching the original doc to the same doc on a new
> link and sending you the new url.
>
> Hal
>
> --- In fqtoxicity@yahoogroups.com, Fqresearch@ wrote:
> >
> > Most, if not all, of those documents are on my server. I have copies
> of
> > the originals. So they are not lost to us even if the FDA were to
> delete
> > them completely. The problem is that the head honchos over at
> wikipedia
> > frown upon me linking back to my site. They seem to think that it is a
> form
> > of self promotion. So what I have to do now is check each and every
> > reference in those articles that link to the FDA site and then update
> them to
> > these new addresses. Which is going to be a royal pain in .... but it
> can be
> > done. It will take weeks to do as I am doing so many things at once.
> So I
> > have to fit that in when I can.
> >
> > It is a constant hassle at wikipedia as I have to monitor all of those
> > articles on a daily basis and undo any changes that are vandalism, etc.
> Those
> > edits that are legit, but I disagree with, I have to discuss with the
> > editor making such changes and see if I can convince them to see things
> from my
> > point of view. As such the articles are in a constant state of flux and
> I
> > have to work my butt off to stop people from undoing all that work. But
> if
> > I can support my position with citations then I win these arguments.
> When
> > the links to my references disappear then you know what hits the fan.
> So
> > I end up like a one legged cat in a room full of rocking chairs.
> >
> > Most of the time when I am short tempered here on the forum it is
> usually
> > when I am battling the medical community over at wikipedia. But it is
> > worth the effort as the articles have the greatest impact possible as
> they are
> > linked to hundreds of thousands of medical sites. So the word is
> getting
> > out to those that matter, and of course those who are now threatened by
> this
> > are fighting back tooth and nail. But there is nobody that I am not
> > willing to go toe to toe with to keep these articles exactly as I have
> written
> > them. But at times I do get a bit punch drunk from all the hits I
> have to
> > endure to make this happen. If that is what it takes then that is
> exactly
> > what I will do.
> >
> > Somebody, somewhere has to go to bat for you guys and gals, and for the
> > moment it is I in the batter's box.
> >
> > capt' dave
> >
> >
> > In a message dated 7/2/2009 4:38:49 P.M. Pacific Daylight Time,
> > newslists@ writes:
> >
> > Hi Dave - Thanks for your time and efforts in keeping these important
> > links "alive". I have no idea how long it will take you to update
> hundreds of
> > references - all I can say is thank you. (and I'd love to add some
> swear
> > words about the FDA, but won't write them here, I'll just continue
> muttering
> > them to myself as I type.)
> >
> > Sue
> >
> > --- In fqtoxicity@yahoogroups.com, "davidtfull" <Fqresearch@> wrote:
> > >
> > > The FDA has changed the locations for every document used as a
> reference
> > within the wikipedia articles that was linked by to the FDA site.
> Thereby
> > invalidating hundreds of references. I now have to go back and change
> > each and every one of these references to reflect these new locations
> > manually. I rather doubt that this was routine housekeeping on their
> part as only
> > the articles that related to the quinolone class were moved recently.
> > >
> > > Looks like they are engaging in damage control once again. They
> cannot
> > delete these articles as that would be destruction of evidence due to
> the
> > ongoing litigation. But nothing would prevent them from moving them
> and
> > invalidating all of the links found on the Internet that makes
> reference to
> > them.
> > >
> > > I've never been one for conspiracy theories regarding these drugs but
> I
> > am seriously reconsidering that view now. Far too much is going on
> > recently for all of this to be coincidence. Too much information has
> disappeared
> > from the Internet, too many sites have shut down, and now this recent
> > action by the FDA who for the most part has failed to update thier site
> with
> > anything relevant for years. Now all of a sudden they are archiving
> anything
> > that has to do with the quinolones?
> > >
> > > capt' dave
> > >
> >
> >
> >
> >
> > ------------------------------------
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> >
> >
> >
> >
> >
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> >
> > [Non-text portions of this message have been removed]
> >
>
>
>
>
> ------------------------------------
>
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>
>
>
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