Hello Dawn,
Most people think on manatees as kind and gentle, but when you spook
one look out! lol.
Yes there are people who breed just for the HYPP disease because it
gives them bigger muscles. There is a test that determines how many
genes the horse carries, N/H means 50% chnce of passing the disease
on while H/H is a 100% chance of passing the disease on. This the
ONLY disease that people breed for. The horse registries want to
stop allowing horses to be registered, but the HYPP vow to sue
because it takes away their free trade and commerce. In other words
it would keep them from becoming million airs. Very few people
realize how serious this is, I have received death threats and most
recently some pro HYPP people have vowed to contact all the MS
organization trying to tell them I am hurting their name by talking
about HYPP and people will be will be withdrawing donations because
of me. They don't realize I am not apart of any MS organization
and this trio is something I am doing on my own.
This is a clear cut of special interests. That is why I am trying to
get public response so when the AQHA gets sued because a few people
want to keep breeding for this disease I can offer them public
support. HYPP is the only disease withy a well funded legal team in
action trying to leep it going. I have NEVER met anyone who is FOR
MS, cancer , AIDS ect.. As you seen in the letter people stand lose
big money if they the AQHA stops allowing HYPP to be registered. I
blame the breed registries for allowing this to coniine Every year
well over half the world champion halter horses are HYPP positive.
The HYPP breeders have a certain ""look" they want there horse to
have. The horses ho don't have the look are sold to the public
without informing them of HYPP. This is weird situation where people
will choose to breed for HYPP because of the demand the AQHA puts on
these horse. The HYPP breeders have no bones about it either. As you
seen in Genes letter. He says hr prefers the disease, explains how
much money he has to lose, and threatens a lawsuit. HYPP has never
really been in the public eye very much. For any of you have not
read the letter please do so and either post or send me a response,
it does not to be long, but let me know if you are for the HYPP
disease or against it. Thanks
Have you ever heard of the The Myelin Repair Foundation (MRF)?
http://www.myelinrepair.org
I have a lot of faith in what they are doing. The fact the doctors
all work together is amazing! I have been in touch with Fred
Schwartz - Philadelphia Area Director and we talked about the
mission coming up with Myelin repair. This is not cure for MS, but
rather a way for the body to reiterate myelin. This could bring
people out of wheel chairs and make a huge impact. I have them
featured on my web site. I have changed some things around adding a
whats new page, FAQ, and a newspaper link located on the updates
page. Check it out! http://www.fightingms.org/

Here is news release from MRF June, 14
NEWS RELEASE

Scientists Identify Molecular "Switches" Affecting Myelin Repair in
Multiple Sclerosis

Tuesday, June 14, 2005 – Saratoga, Calif. – The Myelin Repair
Foundation today announced that its collaboration of five of the
world's leading neuroscientists has identified three new "switches,"
or signals, operating in the brain and spinal column that appear to
turn on and off the nerve cell's ability to repair myelin. Myelin is
the protective coating surrounding nerve cells that is damaged by
MS. The scientists' findings are a critical first step in
understanding myelin repair and its role in treatments for MS and
other demyelinating diseases.
"We believe there are a number of mechanisms at work in MS which
prevent immature brain cells from developing into myelinating cells,
or cause the death of myelinating cells," says Rusty Bromley, COO of
the Saratoga, California-based Myelin Repair Foundation. "We are
excited that just one year into our research program our scientists
have identified three key signals: one which causes the death of
myelinating cells, one which amplifies the production of that
signal, and one which stimulates developing cells to remyelinate.
These findings point to specific opportunities to develop drugs to
repair the damage being caused by Multiple Sclerosis." (See below
for discovery details and references.)

The Myelin Repair Foundation is a nonprofit research foundation
focused exclusively on identifying drug targets that repair myelin
by the year 2009. MRF's team of scientists, working together
virtually, from five different university laboratories in the U.S.
and Canada, have been able to accelerate their research by working
on a common research plan, sharing their findings in real time, and
piggybacking experiments that might otherwise have taken years to
accomplish.

MRF scientists, including Dr. Ben Barres, Professor of Developmental
Biology and Neurobiology at Stanford University School of Medicine;
Dr. David Colman, Director and Penfield Professor at the Montreal
Neurological Institute at McGill University; Dr. Robert Miller,
Professor of Neurosciences at Case Western Reserve University; Dr.
Stephen Miller, Professor of Microbiology-Immunology at Northwestern
University; and Dr. Brian Popko, Professor of Neurology at the
University of Chicago, believe that by working together and sharing
data that they can reduce the time to drug discovery by as much as
75%.
"It's been our goal from day one to accelerate this process," says
MRF President and Founder Scott Johnson. "The team of scientists has
collaborated exceptionally well and the results speak for
themselves. Each small step we take brings us that much closer to
possible treatments and that's our ultimate goal."

Johnson, a former Silicon Valley entrepreneur who suffers from MS,
founded MRF in 2002 with a single purpose: to identify drug targets
that would lead to treatments for MS within five years. The research
team will complete the first year of the five-year research plan on
July 1. To date Johnson has raised $6 million of the $25 million
needed to support the research, including an initial $1 million
donation from Intuit co-founder Scott Cook and a $250,000 award from
Boston biopharmaceutical company Biogen Idec.

"These five scientists and the post docs and students who work in
their labs have exceeded all of our expectations," says
Johnson. "Now we just have to raise enough money to keep pace with
the rate at which they are coming up with new experiments. I can't
say that working within the constraints of our model has been easy
for them. The model is very different from the traditional model of
scientific research. But once the ball got rolling, it just kept
picking up more and more momentum."
Discovery details:
(1) Interferon-ã, a potent chemical signaling molecule secreted by
the reactive immune T cells that create inflammation in MS, creates
sufficient stress on cells during myelin production to kill them
before they can produce myelin.— Wensheng Lin, Heather P. Harding,
David Ron, Brian Popko. 2005. Endoplasmic reticulum stress modulates
the response of myelinating oligodendrocytes to the immune cytokine
interferon-ã. The Journal of Cell Biology Vol. 169, No 4, 630-612
(2) Antigen presenting dendritic cells enter the CNS and stimulate
localized production of new myelin-reactive immune T-cells,
amplifying the production of Interferon-ã, that may act to damage
myelin and prevent myelin repair. —McMahon, E. J., S. L. Bailey, C.
L. Vanderlugt-Castenada, H. Waldner, and S. D. Miller. 2005. Epitope
spreading initiates in the CNS in two mouse models of multiple
sclerosis. Nature Medicine 11:335-339.
(3) The identification of a class of compounds that promote the
final step in the development of myelin producing cells and
stimulates myelin formation. —Ben Barres, Publication pending.
Patent filings are under consideration for all three discoveries.



--- In fightingms1@yahoogroups.com, "Dawn" <dawnsmspage@y...> wrote:
> Hi John!
>
> Thanks for the update....I dont know which story had me laughing
> harder...the manatee or the blue heron!! Sounds like youve had
> enough rain to last a lifetime!!
>
> To answer your questions: Ive read your story on HYPP and Im
trying
> to figure this out...are horses purposlely bred knowing they may
> have this disease and that it will be passed on? That is so sad if
> that is the case. Im not for any type of animal suffering at all.
> :(
>
> and as for the marijuana...Ive never smoked anything in my life
and
> Im not about to start now however if it were legal and in the form
> of a pill I would try it because Ive heard so many positive things
> about it, but for now the whole issue really doesnt effect me
> because Ive never used it therefore have no idea what the benefit
> is.
>
> Take care and keep posting the stories!!
> xoxo
> dawn