In answer to the question about whether Erbitux had to be handled using glass
bottles rather than plastic bags, I asked our oncology pharmacist and she
replied that ImClone is using glass bottles only because they are cheaper.


-Stan

-----Original Message-----
From: experimentalandunconventional@yahoogroups.com
[mailto:experimentalandunconventional@yahoogroups.com]
Sent: Tuesday, May 11, 2004 7:30 AM
To: experimentalandunconventional@yahoogroups.com
Subject: [Experimental and Unconventional] Digest Number 336

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There is 1 message in this issue.

Topics in this digest:

1. RE: Digest Number 335
From: "Stan Radzio" <Stan.Radzio@...>


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Message: 1
Date: Mon, 10 May 2004 08:43:09 -0700
From: "Stan Radzio" <Stan.Radzio@...>
Subject: RE: Digest Number 335


The first dose of Erbitux is administered at 400 mg/square meter.

All subsequent doses of Erbitux are at 200 mg/square meter.

The typical schedule is once a week.

It is administered as a transfusion (glass bottle, no plastic) over a period
ranging from 40 minutes to an hour, then no other chemo drugs for a period of 30
minutes.


-Stan

-----Original Message-----
From: experimentalandunconventional@yahoogroups.com
[mailto:experimentalandunconventional@yahoogroups.com]
Sent: Sunday, May 09, 2004 4:29 AM
To: experimentalandunconventional@yahoogroups.com
Subject: [Experimental and Unconventional] Digest Number 335

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There is 1 message in this issue.

Topics in this digest:

1. Doses - Erbitux v Avastin
From: "www" <www@...>


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Message: 1
Date: Sun, 9 May 2004 00:26:46 +0100
From: "www" <www@...>
Subject: Doses - Erbitux v Avastin

Hi,

I am trying to find out from people who are getting Erbitux or Avastin, what is
the dose they are taking?

I cannot find info on Avastin but, for example from what I have roughly worked
out it MAY work out at 400mg/per sq meter for 1 week then to 200mg/sqm for
following doses of ERBITUX? Is this true? How many pills of what mg is that?Is
it 1 dose a day say 2x 200mg pills in the afternoon?

This compares to Xeloda/Capcebetine Dose level 1250mg/m2 (twice daily) Xeloda
dose calculation according to body surface area, For example Surface Area of
1.53 gives a Dose of 2000mg = 5 pills of 500mg Xeloda am and pm

Thanks

Ian




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