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dysferlin · Dysferlin Deficiency
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repairing RNA   Message List  
Reply | Forward Message #82 of 592 |
Dear sophareth and all,

Ok, to avoid all confusion, you can call me Nat all ( shorter, et
cuter than Phalevi, duh?)

Just checked the scheme in the photos album:

What a pity, the comments are quite difficult to read!
OK, I'll have to clear my understandings about the repair factors
(ribozym?)

When how and why are they activated? are you trying to tell
RNA repair mecanisms could repair any mutated target RNA?
But how to make it them fix a chosen target RNA, on condition the
mutation is
known?(necessity to map the dysferlin gene and sequencing the profil
expression mutations ? and right, microarray methods are very hopeful
in that case and several studies are involved with them..
think we should heard of it from the july NMD conference...)

Isn't that a research work about the understanding and regulation of
RNA expression
and transcription?
Couldn't it be considered like an universal and general processus?...
Applying it to dysferlinopathies as potential way of correction,
might it be
prematured or appropriate (i don't really know...), or just an idea
among others,
an original application idea...

Nat

* part to remove*
Brad i have just the time to send you a wink;-) before returning on
my own bussiness ( just have 2 days off, they pitied me because of
Mrs Ankle!)
Hope you are well and....not too confused.... oops, (hope we shall
time to talk about it later). I apologize for all the confusion.
Ok going back cleaning my mails and the rest which do need it!
A+ and tc
ps, be lenient if i overwhelmed your mail boxes, i have a lot to say
and you know how much i'm talkative, don't you...

Mmmh ...i try the reply way but not sure it worked so i'm re-posting
the message.





Tue Jul 30, 2002 10:06 pm

natalisan
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Message #82 of 592 |
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Dear sophareth and all, Ok, to avoid all confusion, you can call me Nat all ( shorter, et cuter than Phalevi, duh?) Just checked the scheme in the photos...
natalisan
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Aug 27, 2002
2:56 am
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