This image is a complement to my last letter 18 july on RNA-mediated repair of
gene instruction.
sophareth

sophareth <sophareth@...> a écrit : Dear members,

Since the dysferlin gene is known, why antisense/sense paradigm has
not been used more intensively in clinical research? Ce paradigm is
based on the RNA interference mechanism discovered some 3-4 y ago.

Sophareth Camsonne




--- In dysferlin@y..., Daniel MacArthur <danielm@c...> wrote:
> Brad:
> > There are 8 presentations and one discussion workshop on
dysferlin in
> > the program for the upcoming Internatioal Congress on
Neuromuscular
> > Diseases in July 2002. (one of them is co-authored by group
member
> > Daniel MacArthur).
>
> Daniel:
> Thanks for the mention, Brad! While I won't be able to attend the
> Congress myself, several people from my lab will be paying close
> attention to the presentations and posters on dysferlinopathies -
in
> particular the presenting author of the dysferlin/calpain poster,
> Harriet Lo, who started her PhD this year investigating the
diagnosis
> and pathogenesis of dysferlin- and calpain-related muscular
> dystrophies.
>
> While my research has moved away from dysferlin (I'm now working on
> another muscle protein, alpha-actinin-3) I'm still paying close
> attention to the field of dysferlinopathy - firstly because I think
> that understanding dysferlin will greatly illuminate the processes
> behind muscular dystrophy in general, and secondly because it's an
> extremely interesting and fast-moving field.
>
> Brad:
> > I've listed them on the dysferlin website:
> >
> > http://www.dysferlin.org/research.htm#mws2001
>
> Daniel:
> Just a quick question, Brad - I haven't been able to link to your
> website for several weeks, and I was wondering if you were having
> any problems with your server, or if it was more likely to be a web
> problem at my end?
>
> Brad:
> > Although this research might not have any immediate implications
for
> > patients, the number of research groups giving presentations on
this
> > topic is, in my view, a very positive sign.
>
> Daniel:
> I couldn't agree more!
>
>
> Daniel.
>
> Daniel MacArthur
> Institute for Neuromuscular Research
> Neurogenetics Unit
> Clinical Sciences
> The Children's Hospital at Westmead
> Locked Bag 4001, Westmead
> Sydney, NSW 2145
> AUSTRALIA
> Phone: 61-2-9845-3101
> Fax: 61-2-9845-3078
> danielm@c...
>
>
>
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>
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