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Reply | Forward Message #494 of 592 |
Re: [dysferlin] News from Ottawa.

Thank you for your post Mathew, this is the most promising report I've seen! Early days obviously, but still...

Bex

On Sun, Jun 7, 2009 at 1:06 AM, MATHEW anas <matanas@...> wrote:


An article in the news today.
http://www.emaxhealth.com/2/24/31564/stem-cells-stimulate-muscle-regeneration.html


Submitted by ruzik_tuzik on Jun 5th, 2009
Scientists at the Ottawa Hospital Research Institute (OHRI) and the University of Ottawa have discovered a powerful new way to stimulate muscle regeneration, paving the way for new treatments for debilitating conditions such as muscular dystrophy.
The research, to be published in the June 5 issue of Cell Stem Cell, shows for the first time that a protein called Wnt7a increases the number of stem cells in muscle tissue, leading to accelerated growth and repair of skeletal muscle.
“This discovery shows us that by targeting stem cells to boost their numbers, we can improve the body’s ability to repair muscle tissue,” said senior author Dr. Michael Rudnicki. Dr. Rudnicki is the Scientific Director of Canada’s Stem Cell Network and a Senior Scientist at OHRI and Director of OHRI’s Sprott Centre for Stem Cell Research, as well as a Professor of Medicine at the University of Ottawa.
Stem cells give rise to every tissue and organ in the body. Satellite stem cells are specialized muscle stem cells that live in adult skeletal muscle tissue and have the ability to both replicate and differentiate into various types of muscle cells. Dr. Rudnicki’s team found that the Wnt7a protein, when introduced into mouse muscle tissue, significantly increased the population of these satellite stem cells and fueled the regeneration process, creating bigger and stronger muscles. Muscle tissue mass was increased by nearly 20 per cent in the study.
“Our findings point the way to the development of new therapeutic treatment for muscular diseases such as muscular dystrophy, sarcopenia and muscle wasting conditions resulting from extended hospital stays and surgeries,” said Dr. Rudnicki.
This project was funded by the Canadian Institutes of Health Research, the Muscular Dystrophy Association, the National Institutes of Health, the Howard Hughes Medical Institute, Canada’s Stem Cell Network and the Canada Research Chairs Program.
Source: 
Ottawa Health Research Institute



Maybe Brad can give them a call to see if they planing to do any trials in the near future.
I am available...
Also the ACE 31 trial should have conclude by now, but from what i can see no news.


http://www.acceleronpharma.com/content/news/press-releases/list.jsp






Mon Jun 8, 2009 9:38 am

rebeccajread
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Windows Live™: Keep your life in sync. http://windowslive.com/explore?ocid=TXT_TAGLM_WL_t1_allup_explore_022009 Hi, I take magnesium every day. It really...
Sharon Pace
kigcr
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Feb 11, 2009
7:33 pm

an article in an Ontario paper. http://www.thedailyobserver.ca/ArticleDisplay.aspx?e=1571497 clinics in Dom republic and china? i thought cheese are hoaxes. ...
MATHEW anas
vlacas2002
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May 23, 2009
3:13 am

an article in an Ontario paper. http://www.thedailyobserver.ca/ArticleDisplay.aspx?e=1571497 clinics in Dom republic and china? i thought these are hoaxes. ...
MATHEW anas
vlacas2002
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May 23, 2009
3:17 am

has references for muscular dystrophy and muscle in general. The good people @ Jains foundation should put her on the payroll. http://tiny.cc/7tUXW ...
MATHEW anas
vlacas2002
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May 23, 2009
1:28 pm

Mathew, Thanks for posting that lecture. I just finished watching it, it's very good! The site that the link leads to posted the lecture as it pertains to...
baw1064
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May 23, 2009
8:32 pm

An article in the news today. http://www.emaxhealth.com/2/24/31564/stem-cells-stimulate-muscle-regeneration.html All About: General Health Articles Submitted...
MATHEW anas
vlacas2002
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Jun 7, 2009
12:06 am

Thank you for your post Mathew, this is the most promising report I've seen! Early days obviously, but still... Bex ... Thank you for your post Mathew, this is...
Rebecca Read
rebeccajread
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Jun 8, 2009
9:38 am
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