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dysferlin · Dysferlin Deficiency

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1 New Member - 18 New Messages - 1 New File - New Questions

Description

Dysferlin deficiency causes two forms of muscular dystrophy: Miyoshi distal myopathy and Limb-Girdle Muscular dystrophy type 2B. The dysferlin gene and protein were discovered in 1998; many research groups around the world are currently studying this medical condition. This group is intended to give patients, families, researchers, and others the opportunity to share information, experiences, and advice.

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Re: reinventing the wheel?
to my understanding (no scientist here), the delivery method is different for different versions of the the follistatin gene. i rather use the soluble fusion
Posted - Wed Nov 18, 2009 3:16 am
MATHEW anas
vlacas2002
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Re: reinventing the wheel?
Hi Matt, Thank you for the link to Acceleron. Looks promising, but it is a totally different compound than the Myo-29 study that was conducted by Wyeth, which
Posted - Tue Nov 17, 2009 6:54 pm
Thayer, Joshua
joshtc3
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Re: reinventing the wheel?
hey Josh. dont now if you know that accelleron already compleeted phase 1 study for the same or maybe beefed up compounds, as the mda grantees do. that's in
Posted - Tue Nov 17, 2009 4:59 pm
MATHEW anas
vlacas2002
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Re; Myostatin, follistatin, etc.
A brief description on myostatin, etc. to try to make the discussion understandable to everyone. Myostatin is a protein that is a negative regulator of muscle
Posted - Tue Nov 17, 2009 4:48 pm
baw1064
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Re: reinventing the wheel?
Matt, Thank you for the Science Daily link. That is very interesting and encouraging in my opinion. Could you explain why you consider what Dr. Mendell is
Posted - Tue Nov 17, 2009 4:12 pm
Thayer, Joshua
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Message History

Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec
2009 57 16 1 26 5 17 10 23 45
2008 4 3 55 13 12 9 16 16
2007 1 8 3 7 3 1
2006 34 23 20 9 8 7
2005 3 5 2 10
2004 3 6 1 2 1
2003 4 2 2 1 5 1 2
2002 6 13 18 11 3 3 6 2 3
2001 4 10 2 1 2 1
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