Folks,
At today’s APA Annual meeting, the Poster session was dominated by many reports, sponsored by Rockville’s Vanda, on Vanda’s medication paliperidone use in schizophrenia.
As we know, there is considerable pressure to prohibit smoking of hospitalized people with schizophrenia. Providing nicotine replacement, a report found, reduces agitation and ag gression in these patients.
FDA has approved a dissolvable version lamotrigine [Lamictal] and 25mg, 50 mg, 100 mg and 200 mg strengths is expected to be available by July.
Naltrexone is prescribed for alcoholism and for pathological gambling, but a small study in this month’s Amer J on Addictions found that naltrexone didn’t reduce drinking or gambling more than placebo in pts with both disorders. Dosing beg an at 25 mg/d, and was allowed to up to 250 mg. Possible reason that naltrexone failed was that all, including those on placebo, got CBT counseling directed at drinking and gambling.
If your patients are exercising for health reasons, you may want to suggest they NOT take vitamins C or E supplements because a study suggests that those antioxidants block the process through which exercise improve health.
A couple of public developments last week on aripiprazole.&nb sp; Your New-York-Times readers of 8 days ago may have read of a woman who has had depression on and off for decades -- has not had ECT, VNS, DBS, or TMS-- and did have a very good experience with aripiprazole. On the other hand your Wall-Street-Journal readers last week saw an article of Andy Behrman, "a celebrity in the bipolar community," who spoke "glowingly about aripiprazole throughout 2004 and 2005," but now "feels people should know about the side effects of Abilify, as well as the extensive marketing that went into making" that medication "a success." Behrman says that "he later
experienced side effects -- including dazed spells and agitation in his legs -- unpleasant enough that he stopped taking the" medicine "within a year." Bristol-Myers Squibb Co., the maker of Abilify, "says that except for Mr. Behrman, its experience working with patients has been uniformly good, including a current campaign where people tell of their victory over disease without mentioning specific medicines."
NAMI has some general information for veterans in need of psychiatric at: http://www.nami.org/Template.cfm?Section=Veterans_Resources&Template=/ContentManagement/ContentDisplay.cfm&ContentID=53587&lstid=878
In a recent Update, we listed three locations that provide TMS. Now a fourth, Sheppard Pratt.
In 2007 , psychiatrists in Montgomery County noted the vacuous criteria set of many DSM-IV-TR NOSs. Example: Disorders of Infancy, Childhood, or Adolescent NOS: “This category is a residual category for disorders with onset in infancy, childhood, or adolescent that does not meet criteria for any specific disorder in the classification.” WPS made a motion that this be changed in a future printing of the DSM-IV-TR, not waiting for DSM-V to make the corrections. Three days ago, the APA Assembly passed a motion agreeing to new criteria sets, developed by Michael First, MD, NY, and this now goes to the APA’s Board. So, the printing of DSM-IV-TR of 2010 may include those changes.
Roger |
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