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Heart muscle will generate if there is adequate blood supply and nothing around to poison the process. Chelation therapy, of course, provides help in both areas. First, it has multiple effects which improve circulation to the whole heart, not just sections; AND it removes poisons, like mercury, which is found at autopsy in people who had congestive heart failure or cardiomyopathy. With improved circulation and reduced poisons (and regular aerobic exercise) we get more heart muscle(s).
Still, with all the marketing, the companies who dabble in these schemes might be worth investing in for the moment, though I wouldn't bet on it.
Dr. J
-----Original Message-----
From: mrtudo1955 <mrtudo1955@...>
To: chelationtherapy@yahoogroups.com
Sent: Mon, 23 Jun 2008 1:26 am
Subject: [chelationtherapy] New source of heart stem cells found: study
New source of heart stem cells found: study
Sun Jun 22, 1:13 PM ET
PARIS (AFP) - Researchers in the United States have discovered a new
group of stem cells that can give rise to heart muscle cells, known
as cardiomyocytes, according to a study published Sunday.
The stem cells are located in the outermost layer of the heart and
could one day play a critical role in regenerating injured heart
tissue, the researchers say.
"In heart failure, you lose cardiomyocytes, so the only way to
reverse heart failure is to make more of these cells," said William
Pu, the study's lead researcher and a pediatric cardiologist at
Children's Hospital in Boston, Massachusetts.
The new findings come on the heels of two earlier breakthroughs.
In 2006 scientists identified another cardiac stem cell -- marked by
the expression of a gene called Nkx2-5 -- with the potential to
become either heart muscle or cells lining blood vessels in the
organ's left-sided chambers.
Gene expression is the process by which information encoded in the
DNA of a particular gene is transformed into a protein or RNA, which
plays a key role in protein synthesis.
In parallel, other US researchers discovered a related progenitor
heart cell -- so-called because of its capacity to generate different
types of tissue -- that produces the same cell types in the right-
sided heart chambers.
Pu's study, published online in the journal Nature, shows for the
first time that new heart stem cells can also be derived from a third
type of cardiac stell cell, located within the surface of the organ
and identifiable through its expression of a gene called Wt1.
The results were independently verified by another team of scientists
at the University of California in San Diego, whose research was
published in the same issue of Nature.
Pu and colleagues showed that the cells from the heart's outer
lining, called the epicardium, can not only metamorphose into
cardiomyocytes but also into smooth muscle cells, endothelial cells,
which line the interior of blood vessels, and fibroblasts, found in
connective tissue.
"If you are going to regenerate tissue, you need to regenerate the
whole tissue, not just the cardiomyocytes," Pu said in a statement.
The discovery of the new stem cells was an accident. In order to
study the role a different gene in the epicardium, the researchers
labeled cells in live mouse embryos with red fluorescent protein.
"Unexpectedly, we saw that these epicardial cells were becoming
cardiomycytes -- it was a lucky observation," said Pu.
The next challenge, he added, is trying to figure out how a
progenitor stem cell decides to become a certain type of functioning
cell within the heart, and then how to develop methods to trick the
stem cells into transforming into the desired tissue.
"We still don't know how we can manipulate these progenitors," he
said.
Link:
http://news.yahoo.com/s/afp/20080622/ts_afp/healthdiseaseheartstemcell
And
Comedian George Carlin dies of heart failure in Los Angeles at 71
LOS ANGELES (Reuters) - Comedian George Carlin, a counter-culture
hero famed for his routines about drugs and dirty words, died of
heart failure at a Los Angeles-area hospital on Sunday, a spokesman
said. He was 71.
Carlin, who had a history of heart problems, died at St. John's
Health Center in Santa Monica about 6 p.m. PDT (9 p.m. EDT) after
being admitted earlier in the afternoon for chest pains, spokesman
Jeff Abraham told Reuters.
Known for his edgy, provocative material, Carlin achieved status as
an anti-Establishment icon in the 1970s with stand-up bits full of
drug references and a routine about seven dirty words you could not
say on television. A regulatory battle over a radio broadcast of
his "Filthy Words" routine ultimately reached the U.S. Supreme Court.
Sun Jun 22, 1:13 PM ET
PARIS (AFP) - Researchers in the United States have discovered a new
group of stem cells that can give rise to heart muscle cells, known
as cardiomyocytes, according to a study published Sunday.
The stem cells are located in the outermost layer of the heart and
could one day play a critical role in regenerating injured heart
tissue, the researchers say.
"In heart failure, you lose cardiomyocytes, so the only way to
reverse heart failure is to make more of these cells," said William
Pu, the study's lead researcher and a pediatric cardiologist at
Children's Hospital in Boston, Massachusetts.
The new findings come on the heels of two earlier breakthroughs.
In 2006 scientists identified another cardiac stem cell -- marked by
the expression of a gene called Nkx2-5 -- with the potential to
become either heart muscle or cells lining blood vessels in the
organ's left-sided chambers.
Gene expression is the process by which information encoded in the
DNA of a particular gene is transformed into a protein or RNA, which
plays a key role in protein synthesis.
In parallel, other US researchers discovered a related progenitor
heart cell -- so-called because of its capacity to generate different
types of tissue -- that produces the same cell types in the right-
sided heart chambers.
Pu's study, published online in the journal Nature, shows for the
first time that new heart stem cells can also be derived from a third
type of cardiac stell cell, located within the surface of the organ
and identifiable through its expression of a gene called Wt1.
The results were independently verified by another team of scientists
at the University of California in San Diego, whose research was
published in the same issue of Nature.
Pu and colleagues showed that the cells from the heart's outer
lining, called the epicardium, can not only metamorphose into
cardiomyocytes but also into smooth muscle cells, endothelial cells,
which line the interior of blood vessels, and fibroblasts, found in
connective tissue.
"If you are going to regenerate tissue, you need to regenerate the
whole tissue, not just the cardiomyocytes,
The discovery of the new stem cells was an accident. In order to
study the role a different gene in the epicardium, the researchers
labeled cells in live mouse embryos with red fluorescent protein.
"Unexpectedly, we saw that these epicardial cells were becoming
cardiomycytes -- it was a lucky observation,
The next challenge, he added, is trying to figure out how a
progenitor stem cell decides to become a certain type of functioning
cell within the heart, and then how to develop methods to trick the
stem cells into transforming into the desired tissue.
"We still don't know how we can manipulate these progenitors,
said.
Link:
http://news.
And
Comedian George Carlin dies of heart failure in Los Angeles at 71
LOS ANGELES (Reuters) - Comedian George Carlin, a counter-culture
hero famed for his routines about drugs and dirty words, died of
heart failure at a Los Angeles-area hospital on Sunday, a spokesman
said. He was 71.
Carlin, who had a history of heart problems, died at St. John's
Health Center in Santa Monica about 6 p.m. PDT (9 p.m. EDT) after
being admitted earlier in the afternoon for chest pains, spokesman
Jeff Abraham told Reuters.
Known for his edgy, provocative material, Carlin achieved status as
an anti-Establishment icon in the 1970s with stand-up bits full of
drug references and a routine about seven dirty words you could not
say on television. A regulatory battle over a radio broadcast of
his "Filthy Words" routine ultimately reached the U.S. Supreme Court.
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