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Studies do not permit conclusions as to the relative importance of the drug and non-drug factors on weight loss. The natural history of obesity is measured in years, whereas most studies cited are restricted to a few weeks duration; thus, the total impact of drug-induced weight loss over that of diet alone is unknown.

Talk to your doctor about stopping this medication gradually. Do not crush, chew, or open any "once-daily" Medication tablets or capsules. Swallow them whole.

Medication is a sympathomimetic amine, which is similar to an amphetamine. It is also known as an "anorectic" or an "anorexigenic" drug. Medication stimulates the central nervous system (nerves and brain), which increases your heart rate and blood pressure and decreases your appetite.

Take medication exactly as directed. Do not crush, chew, or cut extended-release tablets; swallow them whole. Medication may be habit-forming. Call your doctor if medication loses its effect.

For example, other central nervous system actions or metabolic effects may be involved. Adult obese subjects instructed in dietary management and treated with “anorectic” drugs lose more weight on the average than those treated with placebo and diet, as determined in relatively short-term clinical trials.