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Hydrocodone can be habit-forming. Do not take a larger dose, take it more often, or for a longer period than your doctor tells you to.

Besides, talk to your doctor about the safe use of alcohol. Alcohol may alter the effectiveness of acetaminophen and hydrocodone.

The purpose of the non-controlled drugs in combination is often twofold. 1) To provide increased analgesia via drug synergy. 2) To limit the intake of hydrocodone by causing unpleasant and often unsafe side effects at higher than prescribed doses.

Withdrawal symptoms may occur after you stop taking acetaminophen with hydrocodone. Inform your physician if shortness of breath or breathing difficulty occur.

When taken with alcohol, it can intensify drowsiness. It may interact with monoamine oxidase inhibitors, as well as other drugs that cause drowsiness.

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

It is in FDA pregnancy category C: its effect on an embryo or fetus is not clearly known and pregnant women should consult their physicians before taking it.

Before taking acetaminophen and hydrocodone, tell your doctor and pharmacist if you are allergic to acetaminophen, codeine, hydrocodone, sulfite, or any other drugs.