http://groups.yahoo.com/group/aspartameNM/message/982
diet (aspartame) & migraine: Millichap & Yee, Jan 2003: Murray 3.30.3
rmforall

Pediatr Neurol 2003 Jan; 28(1): 9-15
The diet factor in pediatric and adolescent migraine.
Millichap JG, Yee MM.
Division of Neurology; Children's Memorial Hospital; and Northwestern
University Medical School;, Chicago, Illinois, USA

Diet can play an important role in the precipitation of headaches in
children and adolescents with migraine.

The diet factor in pediatric migraine is frequently neglected in favor
of preventive drug therapy.

The list of foods, beverages, and additives that trigger migraine
includes cheese, chocolate, citrus fruits, hot dogs, monosodium
glutamate, aspartame, fatty foods, ice cream, caffeine withdrawal, and
alcoholic drinks, especially red wine and beer.

Underage drinking is a significant potential cause of recurrent headache
in today's adolescent patients.

Tyramine, phenylethylamine, histamine, nitrites, and sulfites are
involved in the mechanism of food intolerance headache.

Immunoglobulin E-mediated food allergy is an infrequent cause.

Dietary triggers affect phases of the migraine process by influencing
release of serotonin and norepinephrine, causing vasoconstriction or
vasodilatation, or by direct stimulation of trigeminal ganglia,
brainstem, and cortical neuronal pathways.

Treatment begins with a headache and diet diary and the selective
avoidance of foods presumed to trigger attacks.

A universal migraine diet with simultaneous elimination of all potential
food triggers is generally not advised in practice.

A well-balanced diet is encouraged, with avoidance of fasting or skipped
meals.

Long-term prophylactic drug therapy is appropriate only after exclusion
of headache-precipitating trigger factors, including dietary factors.
PMID: 12657413
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Northwestern University 633 Clark Street Evanston, IL 60208
Evanston: 847-491-3741 Chicago: 312-503-8649

Millichap, J Gordon Professor Emeritus, MED-Pediatrics
jgmillichap@...
Department: MED-Pediatrics
office address: 2300 Children's Plaza #BOX 51 Chicago IL 60611-HCMH

Millichap, John J jmillichap@...

http://www.childrensmemorial.org/
Children's Memorial Hospital
2300 Children's Plaza Chicago, Illinois 60614-3394
773-880-4000

Under the leadership of Leon G. Epstein, MD, the Division of Neurology
at Children's Memorial is growing and expanding. The division is adding
to its already impressive roster of physicians and soon expects to care
for even more than the 9,000 children seen annually.
In order to provide the best care possible, the physicians work as a
team with nurses and nurse practitioners with expertise in neurological
disorders. These nurses include: Ann Alpeter, CPNP, Robin Celano, CPNP,
Sonia Davidson, RN, Melissa DeLuca-Glatz, RN, Ann Rovai, RN, Judith
Schmitt, RN, and Michelle Yee, CPNP. (MICHELLE YEE, CPNP)

http://www.childrensmemorial.org/findadoc/bio.asp?UID=144
J. Gordon Millichap, MD Emeritus Professor of Pediatrics,
Feinberg School of Medicine, Northwestern University
Specialties: Neurology
Practices: Children's Memorial Hospital
2300 Children's Plaza (Lincoln and Fullerton)
Chicago, IL 60614
1.800.KIDS DOC (phone) 773.880.6785 (fax)

Medical School: Saint Bartholomew's Hospital and Medical College,
London, England, 1946

Postgraduate Training: Saint Bartholomew's Hospital and
Medical College, 1952, 1951, 1948, 1947, 1946
Hospital for Sick Children, London, 1951

Certification: Board-certified in Electroencephalography, 1975;
Child Neurology, 1965; Neurology, 1960; Pediatrics, 1958
************************************************************************

Rich Murray, MA Room For All rmforall@...
1943 Otowi Road, Santa Fe, New Mexico 87505 USA 505-986-9103

http://groups.yahoo.com/group/aspartameNM/message/959
aspartame review: methanol, formaldehyde, formic acid toxicity:
Murray 3.31.3 rmforall

http://groups.yahoo.com/group/aspartameNM/messages
for 982 posts in a public searchable archive

http://groups.yahoo.com/group/aspartame/ 630 member group

http://groups.yahoo.com/group/aspartameNM/message/968
EU MEPs vote to re-evaluate aspartame and stevia:
Martini: Murray 2.21.3 rmforall

http://www.holisticmed.com/aspartame/scf2002-response.htm
Mark Gold exhaustively critiques European Commission Scientific
Committee on Food re aspartame (12.4.2): 59 pages, 230 references

http://groups.yahoo.com/group/aspartameNM/message/910
formaldehyde & formic acid from methanol in aspartame:
Murray: 12.9.2 rmforall

It is certain that high levels of aspartame use, above 2 liters daily
for months and years, must lead to chronic formaldehyde-formic acid
toxicity, since 11% of aspartame (1,120 mg in 2L diet soda, 5.6 12-oz
cans) is 123 mg methanol (wood alcohol), immediately released into the
body after drinking (unlike the large levels of methanol locked up in
molecules inside many fruits), then quickly transformed into
formaldehyde, which in turn becomes formic acid, both of which in
time become carbon dioxide and water-- however, about 30% of the
methanol remains in the body as cumulative durable toxic metabolites of
formaldehyde and formic acid-- 37 mg daily, a gram every month.
If 10% of the methanol is retained as formaldehyde, that would give 12
mg daily formaldehyde accumulation, about 60 times more than the 0.2 mg
from 10% retention of the 2 mg EPA daily limit for formaldehyde in
drinking water.

Bear in mind that the EPA limit for formaldehyde in
drinking water is 1 ppm,
or 2 mg daily for a typical daily consumption of 2 L of water.

http://groups.yahoo.com/group/aspartameNM/message/835
RTM: ATSDR: EPA limit 1 ppm formaldehyde in drinking water July 1999
5.30.2 rmforall

This long-term low-level chronic toxic exposure leads to typical
patterns of increasingly severe complex symptoms, starting with
headache, fatigue, joint pain, irritability, memory loss, and
leading to vision and eye problems and even seizures. In many cases
there is addiction. Probably there are immune system disorders, with a
hypersensitivity to these toxins and other chemicals.

Confirming evidence and a general theory are given by Pall (2002):
http://groups.yahoo.com/group/aspartameNM/message/909
testable theory of MCS type diseases, vicious cycle of nitric oxide &
peroxynitrite: MSG: formaldehyde-methanol-aspartame:
Martin L. Pall: Murray: 12.9.2 rmforall

http://groups.yahoo.com/group/aspartameNM/message/946
Functional Therapeutics in Neurodegenerative Disease Part 1/2:
Perlmutter 7.15.99: Murray 1.10.3 rmforall

http://groups.yahoo.com/group/aspartameNM/message/915
formaldehyde toxicity: Thrasher & Kilburn: Shaham: EPA: Gold: Murray:
Wilson: CIIN: 12.12.2 rmforall

http://groups.yahoo.com/group/aspartameNM/message/934
24 recent formaldehyde toxicity [Comet assay] reports:
Murray 12.31.2 rmforall

http://groups.yahoo.com/group/aspartameNM/message/935
Comet assay finds DNA damage from sucralose, cyclamate, saccharin in
mice: Sasaki YF & Tsuda S Aug 2002: Murray 1.1.3 rmforall
[Also borderline evidence, in this pilot study of 39 food additives,
using a test group of 4 mice, for DNA damage from for stomach, colon,
liver, bladder, and lung 3 hr after oral dose of 2000 mg/kg aspartame--
a very high dose.]

http://groups.yahoo.com/group/aspartameNM/message/961
genotoxins, Comet assay in mice: Ace-K, stevia fine; aspartame poor;
sucralose, cyclamate, saccharin bad: Y.F. Sasaki Aug 2002:
Murray 1.27.3 rmforall [A detailed look at the data]

http://groups.yahoo.com/group/aspartameNM/message/939
aspartame (aspartic acid, phenylalanine) binding to DNA:
Karikas July 1998: Murray 1.5.3 rmforall
Karikas GA, Schulpis KH, Reclos GJ, Kokotos G
Measurement of molecular interaction of aspartame and
its metabolites with DNA. Clin Biochem 1998 Jul; 31(5): 405-7.
Dept. of Chemistry, University of Athens, Greece
http://www.chem.uoa.gr gkokotos@...

http://groups.yahoo.com/group/aspartameNM/message/960
aspartame & MSG: possible role in autoimmune hepatitis:
Prandota Jan 2003: Murray 1.15.3 rmforall

http://www.dorway.com/tldaddic.html 5-page review
Roberts HJ Aspartame (NutraSweet) addiction.
Townsend Letter 2000 Jan; HJRobertsMD@...
http://www.sunsentpress.com/ sunsentpress@...
Sunshine Sentinel Press P.O.Box 17799 West Palm Beach, FL 33416
800-814-9800 561-588-7628 561-547-8008 fax

http://groups.yahoo.com/group/aspartameNM/message/669
1038-page medical text "Aspartame Disease: An Ignored Epidemic"
published May 30 2001 $ 85.00 postpaid data from 1200 cases
available at http://www.amazon.com
over 600 references from standard medical research
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