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aspartame toxicity brief review: Murray 9.23.2 rmforall   Message List  
Reply | Forward Message #871 of 1590 |
http://groups.yahoo.com/group/aspartameNM/message/871
aspartame toxicity brief review: Murray 9.23.2 rmforall

Rich Murray, MA Room For All rmforall@...
1943 Otowi Road, Santa Fe NM 87505 USA 505-986-9103

http://groups.yahoo.com/group/aspartameNM/messages
for 871 posts in a public searchable archive

http://groups.yahoo.com/group/aspartameNM/message/862 long review

http://groups.yahoo.com/group/aspartameNM/message/860
RTM: FDA: objections to neotame approval 8.3.2 rmforall 38 pages

http://groups.yahoo.com/group/aspartameNM/message/868
Murray: submit complaints and papers to FDA Docket 02P-0317
by Jan 12 2003: Recall Aspartame as a Neurotoxic Drug 9.20.2 rmforall

http://www.dorway.com/tldaddic.html 5-page review
Roberts HJ Aspartame (NutraSweet) addiction.
Townsend Letter 2000 Jan; HJRobertsMD@...
http://www.sunsentpress.com/ sunsentpress@...
Sunshine Sentinel Press P.O.Box 17799 West Palm Beach, FL 33416
800-814-9800 561-588-7628 561-547-8008 fax

http://groups.yahoo.com/group/aspartameNM/message/669
1038-page medical text "Aspartame Disease: An Ignored Epidemic"
published May 30 2001 $ 85.00 postpaid data from 1200 cases
available at http://www.amazon.com
over 600 references from standard medical research
http://www.aspartameispoison.com/contents.html 34 chapters

http://groups.yahoo.com/group/aspartameNM/message/859
RTM: Roberts: the life work of a brilliant clinician:
aspartame toxicity 8.2.2 rmforall

http://groups.yahoo.com/group/aspartameNM/message/790
RTM: Moseley:
review Roberts "Aspartame Disease: An Ignored Epidemic" 2.7.2 rmforall

http://groups.yahoo.com/group/aspartameNM/message/782
RTM: Smith, Terpening, Schmidt, Gums:
full text: aspartame, MSG, fibromyalgia 1.17.2 rmforall
Jerry D Smith, Chris M Terpening, Siegfried OF Schmidt, and John G Gums
Relief of Fibromyalgia Symptoms Following
Discontinuation of Dietary Excitotoxins.
The Annals of Pharmacotherapy 2001; 35(6): 702–706.
Malcolm Randall Veterans Affairs Medical Center, Gainesville, FL, USA.
BACKGROUND: Fibromyalgia is a common rheumatologic disorder that is
often difficult to treat effectively.
CASE SUMMARY: Four patients diagnosed with fibromyalgia syndrome
for two to 17 years are described.
All had undergone multiple treatment
modalities with limited success. All had complete, or nearly complete,
resolution of their symptoms within months after eliminating monosodium
glutamate (MSG) or MSG plus aspartame from their diet.
All patients were women with multiple comorbidities
prior to elimination of MSG.
All have had recurrence of symptoms whenever MSG is ingested.

Siegfried O. Schmidt, MD Asst. Clinical Prof. siggy@...
Community Health and Family Medicine, U. Florida, Gainesville, FL
Shands Hospital
West Oak Clinic Gainesville, FL 32608-3629 352-376-5071

Debbie J. Hypes painfreeliving@... 304-872-4141 (Case # 1 of 4)
P.O Box 25 Lookout, WV 25868-0025 She has about 1,000 on her local
mailing list, and has been a volunteer activist since 1997. Her guide
first came out in 1997: http://www.Pain-Free-Living.net
"The Food Plan: How To Do It" $ 5 by mail, free by email.
Her sister Darlene, now 47, cured her own severe fibromyalgia in 1995
by using an elimination diet, and then Debbie also cured herself by
1997. Their doctor, Siegfried Schmidt, paying attention, tried it on
two selected women, who got well, and are his third and fourth cases.

http://groups.yahoo.com/group/aspartameNM/message/846
RTM: aspartame in Merck Maxalt-MLT worsens migraine,
AstraZeneca Zomig, Eli Lilly Zyprexa,
J&J Merck Pepcid AC (Famotidine 10mg) Chewable Tab,
Pfizer Cool Mint Listerine Pocketpaks 7.16.2 rmforall
Migraine MLT-Down: an unusual presentation of migraine
in patients with aspartame-triggered headaches.
Newman LC, Lipton RB Headache 2001 Oct; 41(9): 899-901.
[Merck 10-mg Maxalt-MLT, for migraine, has 3.75 mg aspartame,
while 12 oz diet soda has 200 mg.]
Headache Institute, St. Lukes-Roosevelt Hospital Center, New York, NY
Department of Neurology newmanache@...
Albert Einstein College of Medicine, Bronx, NY
Innovative Medical Research RLipton@...

http://groups.yahoo.com/group/aspartameNM/message/855
RTM: Blumenthall & Vance:
aspartame chewing gum headaches Nov 1997 7.28.2 rmforall
Harvey J. Blumenthal, MD, Dwight A Vance, RPh
Chewing Gum Headaches.
Headache 1997 Nov-Dec; 37(10): 665-6.
Department of Neurology, University of Oklahoma College of Medicine,
Tulsa, USA. neurotulsa@...
Aspartame, a popular dietetic sweetener, may provoke headache in some
susceptible individuals. Herein, we describe three cases of young women
with migraine who reported their headaches could be provoked by chewing
gum sweetened with aspartame. [6-8 mg aspartame per stick chewing gum]

http://ww.presidiotex.com/barcelona/index.html
Trocho C, Pardo R, Rafecas I, Virgili J, Remesar X,
Fernandez-Lopez JA, Alemany M ["Trok-ho"]
Formaldehyde derived from dietary aspartame binds to tissue
components in vivo. Life Sci 1998 Jun 26; 63(5): 337-49.
Departament de Bioquimica i Biologia Molecular, Facultat de Biologia,
Universitat de Barcelona, Spain.
http://www.presidiotex.com/barcelona/index.html
Maria Alemany, PhD (male) alemany@...

http://groups.yahoo.com/group/aspartameNM/message/864
Murray: Butchko, Tephly, McMartin: Alemany: aspartame formaldehyde
adducts in rats 9.8.2 rmforall
Prof. Alemany vigorously affirms the validity of the Trocho study
against criticism:
Butchko, HH et al [24 authors], Aspartame: review of safety.
Regul. Toxicol. Pharmacol. 2002 April 1; 35 (2 Pt 2): S1-93, review
available for $35, [an industry paid organ]. Butchko:
"When all the research on aspartame, including evaluations in both the
premarketing and postmarketing periods, is examined as a whole, it is
clear that aspartame is safe, and there are no unresolved questions
regarding its safety under conditions of intended use."

http://groups.yahoo.com/group/aspartameNM/message/867
Murray: Thatcher:
simple tests for immune system reactions due to formaldehyde from the
11% methanol in aspartame: Tholen 9.17.2 rmforall

http://groups.yahoo.com/group/aspartameNM/message/628
Rich Murray: Professional House Doctors: Singer: EPA: CPSC:
formaldehyde toxicity 6.10.1 rmforall

http://groups.yahoo.com/group/aspartameNM/message/863
Murray: Wilson: CIIN: EPA: Gold: Thrasher & Kilburn: Shaham:
formaldehyde toxicity 8.22.2 rmforall

http://groups.yahoo.com/group/aspartameNM/message/645
Rich Murray: 18 recent formaldehyde toxicity [Comet assay] abstracts
6.25.1 rmforall

http://groups.yahoo.com/group/aspartameNM/message/622
Rich Murray: Gold: Koehler: Walton: Van Den Eeden: Leon:
aspartame toxicity 6.4.1 rmforall

http://groups.yahoo.com/group/aspartameNM/message/623
Rich Murray: Simmons: Gold: Schiffman: Spiers:
aspartame toxicity 6.4.1 rmforall

http://groups.yahoo.com/group/aspartameNM/message/870
Aspartame: Methanol and the Public Interest 1984:
Monte: Murray 9.23.2 rmforall
Dr. Woodrow C. Monte Aspartame: methanol, and the public health.
Journal of Applied Nutrition 1984; 36 (1): 42-54.
(62 references) Professsor of Food Science
Director of the Food Science and Nutrition Laboratory
Arizona State University, Tempe, Arizona 85287
6411 South River Drive #61 Tempe, Arizona 85283-3337
602-965-6938 woody.monte@...
The methanol from 2 L of diet soda, 5.6 12-oz cans, 20 mg/can, is
112 mg, 10% of the aspartame. The EPA limit for water is 7.8 mg daily
for methanol (wood alcohol), a deadly cumulative poison. Many users
drink 1-2 L daily. The reported symptoms are entirely consistent
with chronic methanol toxicity. (Fresh orange juice has 34 mg/L, but,
like all juices, has 16 times more ethanol, which strongly protects
against methanol.)

"Fruit and vegetables contain pectin with variable methyl ester content.

However, the human has no digestive enzymes for pectin (6, 25)
particularly the pectin esterase required
for its hydrolysis to methanol (26).

Fermentation in the gut may cause disappearance of pectin (6) but the
production of free methanol is not guaranteed by fermentation (3). In
fact, bacteria in the colon probably reduce methanol directly to formic
acid or carbon dioxide (6) (aspartame is completely absorbed before
reaching the colon). Heating of pectins has been shown to cause
virtually no demethoxylation; even temperatures of 120 deg C produced
only traces of methanol (3). Methanol evolved during cooking of high
pectin foods (7) has been accounted for in the volatile fraction during
boiling and is quickly lost to the atmosphere (49).
Entrapment of these volatiles probably accounts for the elevation in
methanol levels of certain fruit and vegetable products
during canning (31, 33)."

Recent research [see links at end of post] supports his focus on the
methanol to formaldehyde toxic process:

"The United States Environmental Protection Agency in their Multimedia
Environmental Goals for Environmental Assessment recommends a minimum
acute toxicity concentration of methanol in drinking water at 3.9 parts
per million, with a recommended limit of consumption below 7.8 mg/day
(8). This report clearly indicates that methanol:

"is considered a cumulative poison
due to the low rate of excretion once it is absorbed.
In the body, methanol is oxidized to formaldehyde and
formic acid; both of these metabolites are toxic." (8)....

Recently the toxic role of formaldehyde (in methanol toxicity) has been
questioned (34). No skeptic can overlook the fact that, metabolically,
formaldehyde must be formed as an intermediate to formic acid
production (54).

Formaldehyde has a high reactivity which may be why it
has not been found in humans or other primates during methanol
poisioning (59)....

If formaldehyde is produced from methanol and does have a reasonable
half life within certain cells in the poisoned organism the chronic
toxicological ramifications could be grave.

Formaldehyde is a known
carcinogen (57) producing squamous-cell carcinomas by inhalation
exposure in experimental animals (22). The available epidemiological
studies do not provide adequate data for assessing the carcinogenicity
of formaldehyde in man (22, 24, 57).

However, reaction of formaldehyde
with deoxyribonucleic acid (DNA) has resulted in irreversible
denaturation that could interfere with DNA replication and result in
mutation (37)...."

http://www.dorway.com/barua.html
Dr. J. Barua (ophthalmic surgeon), Dr. Arun Bal (surgeon)
Emerging facts about aspartame.
Journal Of The Diabetic Association Of India 1995; 35 (4):
(79 references) barua@...
"...the total amount of methanol absorbed will be approximately
10% of aspartame ingested. An EPA assessment of methanol states
that methanol, 'is considered a cumulative poison due to the low rate
of excretion once it is absorbed. The absorbed methanol is then
slowly converted to formaldehyde...'"
"Reaction of formaldehyde with DNA has been observed,
by spectrophotometry and electron microscopy, to result in
irreversible denaturation."
"DKP has been implicated in the occurence of brain tumors."

http://groups.yahoo.com/group/aspartameNM/message/804
RTM: Hetle & Eltervaag: 2001 thesis
abstract: aspartame brain damage in mice:
Sonnewald 1995 study full text 2.17.2 rmforall

http://groups.yahoo.com/group/aspartameNM/message/346
WebMD: Barclay: Barth:
survey shows aspartame hurts memory in students 11.9.00
http://www.psy.tcu.edu/psy/barth.htm
Timothy M. Barth Department of Psychology t.barth@...
Texas Christian University TCU Box 298920 Fort Worth, TX 76129
Chairman, Physiological Psychology 817-921-7410

http://groups.yahoo.com/group/aspartameNM/message/760
Kovatsi L, Tsouggas M
The effect of oral aspartame administration on the
balance of magnesium in the rat.
Magnes Res 2001 Sep;14(3): 189-94.
Laboratory of Forensic Medicine & Toxicology, Faculty of Medicine
Aristotle University of Thessaloniki, Greece kovatsi@...

http://groups.yahoo.com/group/aspartameNM/message/689
Karikas GA, Schulpis KH, Reclos GJ, Kokotos G
Measurement of molecular interaction of aspartame and
its metabolites with DNA. Clin Biochem 1998 Jul; 31(5): 405-7.
Dept. of Chemistry, University of Athens, Greece
http://www.chem.uoa.gr gkokotos@...

http://www.medscape.com/MedGenMed/braintumors
Lennart Hardell, M.D., PhD, in 1999 reported in Sweden that both
cell phone use and heavy aspartame use correlate with increased
brain cancers lennart.hardell@... +46 19 602 15 46

http://groups.yahoo.com/group/aspartameNM/message/31
Murray: Wurtman: aspartame & seizures 11.9.85 10.30.99
Wurtman RJ Aspartame: possible effect on seizure susceptibility.
Lancet 1985 Nov 9; 2(8463): 1060.
Richard J. Wurtman, Ph.D. dick@... 617-253-3091
Professor of Neuroscience
Prof. of Health Sciences and Technology
Massachusetts Institute of Technlogy Cambridge, Mass. 02139

http://groups.yahoo.com/group/aspartameNM/message/32
Murray: Drake: aspartame & panic attacks 9.13.86 10.30.99 rmforall
Miles E. Drake, MD
Panic attacks and excessive aspartame ingestion.
Lancet 1986 Sep 13; 2(8507): 631.
Department of Neurology and Psychiatry,
Ohio State University Medical Center, Columbus, Ohio 43210, USA

http://www.dorway.com/blayenn.html
Russell L. Blaylock, MD dodd@...
Excitotoxins, neurodegeneration and neurodevelopment.
The Medical Sentinel Journal 1999 Fall; (95 references)
russell@... 601-982-1175

http://www.truthinlabeling.org/ Truth in Labeling Campaign [MSG]
Adrienne Samuels, PhD The toxicity/safety of processed
free glutamic acid (MSG): a study in suppression of information.
Accountability in Research 1999; 6: 259-310. 52-page review
P.O. Box 2532 Darien, Illinois 60561
858-481-9333 adandjack@...

http://groups.yahoo.com/group/aspartameNM/message/841
RTM: Merisant Co., MSD Capital, Dell Computer Corp., NutraSweet Co.,
JW Childs Assc.: aspartame-neotame toxicity 7.10.2 rmforall

http://groups.yahoo.com/group/aspartameNM/message/857
RTM: www.dorway.com: original documents and long reviews of flaws in
aspartame toxicity research 7.31.2 rmforall

http://www.dorway.com David O. Rietz over 12,000 print pages
Mission-Possible-USA Betty Martini 770-242-2599
Bettym19@... dorietz@...
http://www.dorway.com/asprlink.html many links
http://www.dorway.com/nslawsuit.txt Jeff Martin, Attorney
http://www.dorway.com/upipart1.txt
UPI reporter Gregory Gordon: 96K 3-part expose Oct 1987
http://www.dorway.com/doctors.txt
What many informed doctors are saying/have said about aspartame

http://www.HolisticMed.com/aspartame 603-225-2100
Aspartame Toxicity Information Center Mark D. Gold
mgold@... 12 East Side Drive #2-18 Concord, NH 03301
http://www.holisticmed.com/aspartame/abuse/methanol.html
"Scientific Abuse in Aspartame Research"

Aspartame Consumer Safety Network and Pilot Hotline [1987-2001]
Mary Nash Stoddard, Founder & President
P.O. Box 780634 Dallas, TX 75378 .
214-352-4268 marystod@...
http://web2.airmail.net/marystod/index.html
http://web2.airmail.net/marystod/espanol.htm
Toxicology Sourcebook: "Deadly Deception: Story of Aspartame"

http://groups.yahoo.com/group/aspartameNM/message/858
RTM: Samuels: Strong: Roberts: Gold: flaws in double-blind studies re
aspartame and MSG toxicity 8.1.2 rmforall

"Survey of aspartame studies: correlation of outcome and funding
sources," 1998, unpublished: http://www.dorway.com/peerrev.html
Walton found 166 separate published studies in the peer reviewed
medical literature, which had relevance for questions of human safety.
The 74 studies funded by industry all (100%) attested to aspartame's
safety, whereas of the 92 non-industry funded studies, 84 (91%)
identified a problem. Six of the seven non-industry funded studies
that were favorable to aspartame safety were from the FDA, which
has a public record that shows a strong pro-industry bias.
Ralph G. Walton, MD, Prof. of Clinical Psychology, Northeastern Ohio
Universities, College of Medicine, Dept. of Psychiatry, Youngstown,
OH 44501, Chairman, The Center for Behavioral Medicine,
Northside Medical Center, 500 Gypsy Lane, P.O. Box 240 Youngstown,
OH 44501 330-740-3621 rwalton193@...
http://www.neoucom.edu/DEPTS/Psychiatry/walton.htm

http://google.com gives 105,000 websites for "aspartame" , while
http://groups.google.com/ finds on 700 MB of posts from 20-years of
Usenet groups, 72,300 posts, and
http://www.AllTheWeb.com gives 177,012, the top four being leading and
very well informed volunteer anti-aspartame sites.
http://www.ncbi.nlm.nih.gov/PubMed/ lists 712 aspartame items.

http://www.readthelabel.org.uk/ Additives Survivors' Network (UK)
geoffbrewer@...

http://www.aspartame.ca/ John T. Linnell admin@...
http://www.aspartame.ca/page_a10.html
Canadian Class Action Law Suit

http://groups.yahoo.com/group/aspartameNM/message/802
RTM: 700.club.com: CBN:
Totheroh & Robertson: aspartame expose 2.13.2 rmforall

http://groups.yahoo.com/group/aspartameNM/message/805
RTM: Ive:
UK Daily Mirror Magazine: aspartame toxicity 2.18.2 rmforall

http://groups.yahoo.com/group/aspartameNM/message/813
[also on http://www.rense.com/general20/bushaspertameAL.htm
Contact Jeff Rense <jr@...> ]
RTM: (corrected)
danger to President Bush from aspartame toxicity 2.24.2 rmforall

http://www.vegsource.com extensive vegan information
http://www.vegsource.com/articles/kradjian_milk.htm
Robert Kradjian MD Discusses Milk
**********************************************************

Serious symptom syndrome summary:
Aspartame (NutraSweet, Equal, Canderel, Benevia) is reported by
scientific studies and case histories to be toxic: * headaches
* many body and joint pains (or burning, tingling, tremors, twitching,
spasms, cramps, or numbness) * fever, fatigue
* "mind fog", "feel unreal", poor memory, confusion, anxiety,
irritability, depression, mania, insomnia, dizziness, slurred speech,
ringing in ears, sexual problems, poor vision, hearing, or taste
* red face, itching, rashes, burning eyes or throat,
dry mouth or eyes, mouth sores * hair loss
* obesity, bloating, edema, anorexia,
poor or excessive hunger or thirst * breathing problems
* nausea, diarrhea or constipation * coldness * sweating
* racing heart, high blood pressure, erratic blood sugar levels
* seizures * birth defects * brain cancers * addiction
* aggrivates diabetes, autism, ADHD, allergies,
and interstitial cystitis (bladder pain)
**********************************************************

http://members.tripod.com/~mission_possible/scotland_branch.html
http://www.aspartame.ca/ Canada
http://www.geocities.com/HotSprings/4578/ Canada
http://www.cybernaute.com/earthconcert2000/AspartaMalcache.htm
http://www.reseauproteus.net/therapies/nutritio/aspartame.htm
http://ww2.grn.es/avalls/aspa1.htm Spain
http://www.geocities.com/HotSprings/Falls/8669/ Brazil
http://www.phd.com.br/aspartame.htm
http://hem.passagen.se/mission.possible.sweden/
http://home.online.no/~dusan/foods/aspartame.html Norway
http://www.aspartaam.nl/info/product.html Holland, in Dutch
http://www.laleva.org/ Italy
http://www.laleva.org/alimenti/dorwayaspartame.html
http://users.westnet.gr/~cgian/aspartame.htm Greece
**********************************************************







Tue Sep 24, 2002 7:51 am

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http://groups.yahoo.com/group/aspartameNM/message/871 aspartame toxicity brief review: Murray 9.23.2 rmforall Rich Murray, MA Room For All...
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