http://groups.yahoo.com/group/aspartameNM/message/1004
the issue of aspartame toxicity: Forman: Murray 6.27.3

June 27 2003 I was very attracted to Gov. Howard Dean, MD last weekend,
when I first heard about him and visited his website. I sense that this
leader can be fully trusted.

http://dfa.convio.net/site/PageServer?pagename=homepage
Paul Forman, policy issues for Howard Dean's Presidential campaign
pforman@...

The European Parliament voted April 9 440 to 20 to have the safety of
aspartame reevaluated within 12 months. This is the first such
governmental challenge anywhere in the world since Donald Rumsfeld, CEO
of Searle Laboratories in 1977, used his powerful Washington connections
to force the FDA to approve aspartame in July, 1981, against the vote of
its own scientific Board of Inquiry.

Searle admitted in a research study in Oct 1973 in J. Nutrition by their
own lab, J.A. Oppermann et al, that the inevitable and immediate
products of the 11% methanol component of aspartame are the toxins
formaldehyde and formic acid. If only 10% of the methanol from 6 cans
of diet soda becomes permanent toxic products of formaldehyde daily,
that is sixty times the EPA limit for formaldehyde retained from daily
drinking water. A number of varieties of typical serious symptom suites
are readily discerned in thousands of citizen and physician reports. A
1% increase in the incidence in symptoms ranging from headache to
ideopathic seizures would be millions of cases yearly worldwide, yet be
undiscernable in almost all scientific surveys and even in large-scale
double-blind clinical tests-- even if funding were available for truly
objective, unbiased, and complete studies. Indeed, about a hundred
millon dollars has been spent yearly to proclaim that aspartame
(NutraSweet and Equal) are "the most tested food additive in history".

The term "food additive" is significant-- for it was arbitarily assigned
by adroit and largely hidden maneuvers, and means practically that the
industry is not required to prove its safety nor keep records of citizen
and physician complaints. As in the case of tobacco, decades of
entrenched corporate greed have created immense gratuitous human
suffering and cripling damage to society and its institutions.

It is sadly relevant that the public record shows that heavy users of
diet sodas and other aspartame products include the President, Al Gore,
and Bill Clinton.

The first public voice to speak out about this tragegy will reap much
deserved credit for alerting the people and spotlighting the need for
fundamental reforms: the Precautionary Principle, major reforms of the
FDA and EPA, public financing of all elections, and the elimination of
undue influence by vast vested interests.

Were it not for the remarkable evolution of the Net as a global forum
since 1995, and the efforts of a dozen volunteer citizen activists, the
world public would be still be defenseless against this outrage.
Leaders who act will quickly earn the approval of this global forum of
700 million worldwide, as this year a new global political process
emerges, in which excellence easily defeats mediocrity (I should say,
media-crity).

I recommend contacting the many informed experts, laymen and
professionals, listed for your convenience in this research summary.

Rich Murray
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http://groups.yahoo.com/group/aspartameNM/message/1002
http://groups.yahoo.com/group/aspartame/message/15477
aspartame review: methanol, formaldehyde, formic acid toxicity:
Murray 6.27.3 rmforall

Rich Murray, MA Room For All rmforall@...
1943 Otowi Road, Santa Fe, New Mexico 87505 USA 505-986-9103

http://groups.yahoo.com/group/aspartameNM/message/983
aspartame & formaldehyde toxicity: Murray 6.27.3 rmforall

http://groups.yahoo.com/group/aspartameNM/messages
for 1004 posts in a public searchable archive 103 members

http://groups.yahoo.com/group/aspartame/ 15494 posts 682 members

http://groups.yahoo.com/group/aspartameNM/message/989
EU votes 440 to 20 to approve sucralose, limit cyclamates & reevaluate
aspartame & stevia: Murray 4.12.3 rmforall

http://www.holisticmed.com/aspartame/scf2002-response.htm
Mark Gold exhaustively critiques European Commission Scientific
Committee on Food re aspartame (12.4.2): 59 pages, 230 references

http://groups.yahoo.com/group/aspartameNM/message/910
formaldehyde & formic acid from methanol in aspartame:
Murray: 12.9.2 rmforall

It is certain that high levels of aspartame use, above 2 liters daily
for months and years, must lead to chronic formaldehyde-formic acid
toxicity, since 11% of aspartame (1,120 mg in 2L diet soda, 5.6 12-oz
cans) is 123 mg methanol (wood alcohol), immediately released into the
body after drinking (unlike the large levels of methanol locked up in
molecules inside many fruits), then quickly transformed into
formaldehyde, which in turn becomes formic acid, both of which in
time are partially eliminated as carbon dioxide and water.

However, about 30% of the methanol remains in the body as cumulative
durable toxic metabolites of formaldehyde and formic acid-- 37 mg daily,
a gram every month. [J. Nutrition 1973 Oct; 103(10): 1454-1459.
Metabolism of aspartame in monkeys. Oppermann JA, Muldoon E, Ranney RE.]
If 10% of the methanol is retained as formaldehyde, that would give 12
mg daily formaldehyde accumulation, about 60 times more than the 0.2 mg
from 10% retention of the 2 mg EPA daily limit for formaldehyde in
drinking water.

Bear in mind that the EPA limit for formaldehyde in drinking water is
1 ppm, or 2 mg daily for a typical daily consumption of 2 L of water.

http://groups.yahoo.com/group/aspartameNM/message/835
RTM: ATSDR: EPA limit 1 ppm formaldehyde in drinking water July 1999
5.30.2 rmforall

This long-term low-level chronic toxic exposure leads to typical
patterns of increasingly severe complex symptoms, starting with
headache, fatigue, joint pain, irritability, memory loss, and
leading to vision and eye problems, and even seizures. In many cases
there is addiction. Probably there are immune system disorders, with a
hypersensitivity to these toxins and other chemicals.

Confirming evidence and a general theory are given by Pall (2002):
http://groups.yahoo.com/group/aspartameNM/message/909
testable theory of MCS type diseases, vicious cycle of nitric oxide &
peroxynitrite: MSG: formaldehyde-methanol-aspartame:
Martin L. Pall: Murray: 12.9.2 rmforall

http://groups.yahoo.com/group/aspartameNM/message/946
Functional Therapeutics in Neurodegenerative Disease Part 1/2:
Perlmutter 7.15.99: Murray 1.10.3 rmforall

http://google.com gives 149,000 websites for "aspartame" , with the top
9 listings being anti-aspartame, while
http://groups.google.com/ finds on 700 MB of posts from 20 years of
Usenet groups, 79,300 posts, the top 10 being anti-aspartame.
http://www.AllTheWeb.com gives 239,091, the top 5 being leading and
very well informed volunteer anti-aspartame sites.
http://teoma.com/index.asp gives 42,900 websites, the top 7 are anti.
http://www.ncbi.nlm.nih.gov/PubMed/ lists 734 aspartame items.

http://groups.yahoo.com/group/aspartameNM/message/915
formaldehyde toxicity: Thrasher & Kilburn: Shaham: EPA: Gold: Murray:
Wilson: CIIN: 12.12.2 rmforall

http://groups.yahoo.com/group/aspartameNM/message/934
24 recent formaldehyde toxicity [Comet assay] reports:
Murray 12.31.2 rmforall

http://groups.yahoo.com/group/aspartameNM/message/935
Comet assay finds DNA damage from sucralose, cyclamate, saccharin in
mice: Sasaki YF & Tsuda S Aug 2002: Murray 1.1.3 rmforall
[Also borderline evidence, in this pilot study of 39 food additives,
using a test group of 4 mice, for DNA damage from for stomach, colon,
liver, bladder, and lung 3 hr after oral dose of 2000 mg/kg aspartame--
a very high dose.]

http://groups.yahoo.com/group/aspartameNM/message/961
genotoxins, Comet assay in mice: Ace-K, stevia fine; aspartame poor;
sucralose, cyclamate, saccharin bad: Y.F. Sasaki Aug 2002:
Murray 1.27.3 rmforall [A detailed look at the data]

http://groups.yahoo.com/group/aspartameNM/message/939
aspartame (aspartic acid, phenylalanine) binding to DNA:
Karikas July 1998: Murray 1.5.3 rmforall
Karikas GA, Schulpis KH, Reclos GJ, Kokotos G
Measurement of molecular interaction of aspartame and
its metabolites with DNA. Clin Biochem 1998 Jul; 31(5): 405-7.
Dept. of Chemistry, University of Athens, Greece
http://www.chem.uoa.gr gkokotos@...

http://groups.yahoo.com/group/aspartameNM/message/960
aspartame & MSG: possible role in autoimmune hepatitis:
Prandota Jan 2003: Murray 1.15.3 rmforall

http://www.dorway.com/tldaddic.html 5-page review
Roberts HJ Aspartame (NutraSweet) addiction.
Townsend Letter 2000 Jan; HJRobertsMD@...
http://www.sunsentpress.com/ sunsentpress@...
Sunshine Sentinel Press P.O.Box 17799 West Palm Beach, FL 33416
800-814-9800 561-588-7628 561-547-8008 fax

http://groups.yahoo.com/group/aspartameNM/message/669
1038-page medical text "Aspartame Disease: An Ignored Epidemic"
published May 30 2001 $ 85.00 postpaid data from 1200 cases
available at http://www.amazon.com
over 600 references from standard medical research
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