Jenny,

Personally, I would not wait 12 hours inbetween. I've always been
told, its okay to give them their meds an hour before or after the regular
time, but they do not recoomend waiting much longer. Like I mentioned
before, while she is sleeping you can try to give her the meds by simply
getting her to open her mouth just a bit and then shoot the oral meds in.
They automatically swallow. She is going to have to get use to the taste.
Its really not that bad. I've tasted it myself. The sooner she realizes
she has to take the meds when you say she does, the easier it will be for
you in the long run. This is a lifetime responsibility.

Debbie