This was the question and the answer follows:

Q: I was searching around for the meds my son uses...he is now on
75 mg. of Imipramine (and 10mg Lorazepam)...so what kind of relation
is this to what I noticed on the website--Clomipramine...sounds kinda
like Clondine & Imipramine together...or is that a coincidence??

A: "Clomipramine is simply imipramine with a chloride atom added
onto it. That very small change makes a very big difference. It
gives the new med extra SRI (serotonin increasing) action which makes
Clomipramine a better anxiety med and gives it good OCD (obsessive
compulsive disorder) benefit which imipramine doesn't have.
Clonidine is unrelated. I don't know your son's age, weight, or the
target symptoms (i.e., what the meds are supposed to be helping) but
lorazepam 10 mg is a very big dose; 1 mg makes more sense. Lorazepam
(=Ativan) is usually used for panic attacks or sleep or temper and
not given every day to kids as it has a small habit forming effect.
Imipramine is a fine old med but the newer meds are often, but not
always, an improvement. You might want to talk more with your son's
doctor."

Source;
Dr. Kevin Leehay M.D.

Paul Marshall
http://paul.tourette.info
Tourette - Updates
http://groups.yahoo.com/group/Tourette-Updates