AIDS virusi bowaqlar qinida tiz yoshurnidu

Towendiki xewerde dokilat qilishiche AIDS ni dawalsh dorisigha
qarshi kuchi bar yeni dora tesir qilmaydighan AIDS virusi apidin
baligha yuqqandin kiyin, balining imiyunut sistimisidiki hujeyriler
ichige yoshurnup, bir nechche yilliq yoshurun mezgilni bishidin
otkuzidiken. Bu balilar arisidiki AIDS ni dawalashta alahide
tosqunluq rol oynaydiken.

Amirkida apisi AIDS virusi bilen yuqumlanghanlarning balisigha
yuqturush nisbiti texminen 25% bolsimu, biraq tereqqi qiliwatqan
dowletlerde bu nisbet xilila yuquri iken.

AIDS ni dawalsh dorisigha qarshi kuchi bar yeni dora tesir
qilmaydighan AIDS virusi dawalash eslidin qiyin bolghan AIDS
kisilini tiximu murekkepleshturmekte, AIDS ni dawalsh dorisigha
qarshi kuchi bar yeni dora tesir qilmaydighan AIDS virusi dawalash
eslidin qiyin bolghan AIDS kisilini tiximu murekkepleshturmekte, we
AIDS kisilige giriptar bolghan balilarning dawalash unimining towen
bolushigha sewep bolmaqta.

Memet Emin


AIDS virus hides quickly inside babies' blood

Reuters Health

Monday, April 30, 2007

WASHINGTON (Reuters) - Drug-resistant versions of the AIDS virus
passed from mother to child can quickly hide in the infant's immune
system cells and lurk for years, researchers reported on Monday.
This will limit what drugs the children can take to control their
infection, Dr. Deborah Persaud of Johns Hopkins University School of
Medicine in Baltimore and colleagues said.

While mother-to-child transmission of the AIDS virus has been slowed
in the United States by giving drugs to both the mother and the baby
at the time of birth, it is still a major cause of HIV infection in
the developing world.

If not treated, about 25 percent of newborns get the virus from
their infected mothers, either during birth or shortly after, while
breastfeeding.

Drug-resistant versions of the human immunodeficiency virus are also
a growing problem. People develop resistance while taking AIDS
drugs, but then this resistant virus can be passed from one person
to another.

Persaud's team studied 21 HIV-infected infants in 10 U.S. states.
They found five of them were infected with drug-resistant HIV from
their mothers.

The virus moved quickly to so-called resting or inactive CD4 T-
cells -- the cells normally infected by HIV, Persaud's team reported
in The Journal of Infectious Diseases.

The virus was resistant to a class of AIDS drugs called non-
nucleoside reverse transcriptase inhibitors or NNRTIs. But protease
inhibitors, another class of AIDS drugs, worked, the researchers
found.

"The initial transmitted drug-resistant virus will likely never be
cleared from that infant with currently available treatments,"
Persaud said in a statement.

The AIDS virus is especially difficult to fight because it infects
the immune system cells that usually battle a viral infection.
Single drugs do very little to control it, so it is important to use
cocktails of drugs that interfere with the virus at various points
in its life cycle.

There are currently about 20 different available AIDS drugs in
various classes, but patients with resistant virus automatically
cannot use several of them.

Reuters Health