New research has shown that Alzheimer's disease may be the
result of insulin resistance of neuron synapses in the brain.
High levels of insulin accelerates Alzheimer's. So in
insulin resistant patients, flooding their bodies with
additional insulin may be contributing to the development
of Alzheimer's.
The answer may be drugs that lower insulin resistance (like
Metformin and Pioglitizone) combined with weight loss (fat
increases insulin resistance).
Every day there is more and more evidence that hyper-
insulinemic type 2 diabetes is NOT best treated with
more insulin.
C. Marley, M.D.
Ellis: {Hello Dr. Marley. I never said that anybody should
FLOOD their body with insulin. I, and everybody, should use
THE RIGHT DOSE of insulin, AT THE RIGHT TIME, in order to
keep blood glucose near 85 or to bring it down as fast
as possible if it is higher than 100, so that it doesn't
cause sugar-damage...
Insulin resistance is caused by previously high blood
glucose levels, which caused the pancreas to release high
levels of insulin, which overstimulated the insulin receptors
of cells. The brain happens to be nervous tissue, and
nervous tissue is one of the ones that is most damaged by
high blood glucose... so it is very possible that high blood
glucose would also cause high insulin resistance.
That does not mean that the RIGHT DOSE at the RIGHT TIME
causes Alzheimer's... that means that THE LACK OF THE
RIGHT DOSE AT THE RIGHT TIME ultimately causes Alzheimer's
because it causes the brain cells to become insulin
resistant...
And lowering insulin resistance and causing the pancreas
to burn out beta cells because you turn it ON when you
could have let it REST by injecting insulin, is not a
very good idea, either. You have said before that you
don't agree that beta cells "burn out"... but Dr. Bernstein
believes that beta cell burn out when they are forced to
work when they could have been resting... and I agree
with Dr. Bernstein.
Thanks for writing... - Ellis}