Clinical Overview of Alan P. Mintz, MD
by Jeffry S. Life, MD, PhD
June 11, 2007

Dr. Alan P. Mintz was admitted to the hospital about six
weeks prior to his passing. He presented with a history
of a gradual onset of profound weakness and fatigue along
with the abrupt onset of an abnormal gait and mild confusion.

Weakness and fatigue developed in early January 2007 shortly
after he sustained an exercise-related head injury. A bar and
heavy weights accidentally fell on him, striking the back of
his head.

Initial diagnostic testing after hospitalization included a
CT and MRI of his brain; CT scans of his chest, abdomen and
pelvis; two spinal taps to analyze cerebrospinal fluid; and
a transesophageal echocardiogram. The only positive findings
were a non-diagnostic abnormality noted on the MRI of his
brain.

The echocardiogram demonstrated a patent foramen ovale (a
congenital hole between the upper chambers of the heart).

The radiologists were unclear as to the cause of the abnormality
noted on the MRI. All tests were negative for cancer, infection,
inflammation or any other disease process.

Lacking a definitive diagnosis or explanation for his condition,
Dr. Mintz and his team of medical specialists concluded that a
brain biopsy was necessary, so appropriate treatment could be
initiated. However, the results of the brain biopsy proved to
be negative for any disease process.

Extensive review of the biopsy was carried out in Las Vegas as
well as at the Mayo Clinic and UCLA Medical Center.

Dr. Mintz developed an intracerebral hemorrhage at the biopsy
site shortly after the procedure was completed. Bleeding into the
brain after a biopsy is a known but low risk associated with this
procedure. Dr. Mintz died about four weeks after the biopsy as
a result of the intracerebral hemorrhage.

Dr. Alan Mintz personified all the age management medical goals
of the Cenegenics program, which he cofounded. Those goals include
achieving optimal physical and mental health and function by
following a lifestyle consisting of the best nutrition, regular
exercise and maintaining normal and healthy hormone levels.

Dr. Mintz achieved his goal of a vital and excellent quality of
life until very near the time of his death. He will be greatly missed
by his personal family, his Cenegenics family and by thousands of
patients and friends who so admired and respected him and his work.