Tracing its history during the battle of Solferino, Italy on June 24, 1859, the Red Cross Youth of the University of the Philippines Los Baños was established on June 25, 1975 as one of the components of the premier humanitarian movement in the world. It has for many years carried out the Seven Fundamental Principles of the Movement: Humanity, Impartiality, Neutrality, Independence, Voluntary service, Unity and Universality.

Red Cross Youth of UPLB conducts a wide range of activities and trainings, notably blood donations, first aid training, disaster preparedness management training, free medical and dental missions, first aid stationing, water safety and survival, and education programs on AIDS, Drug abuse, and the Laws of War (International Humanitarian Law). It is also very active in the field of youth development with a pool of youth trainers and facilitators trained to cater to requests for Leadership Training Seminars, Parliamentary Procedures training, Youth volunteers’ conference, HIV-AIDS and Drug Abuse seminars, International Humanitarian Law and First aid demonstrations.

The organization has received numerous awards within and outside the university. It received the Three Outstanding Youth Organization in the Philippines award in 1996, Department of Health blood provider’s award, Honor roll award for blood donation and championship awards in first aid competitions including the much coveted Southeast and East Asian First Aid Competition in 2002.

The organization has assisted numerous UPLB constituents, especially those who need blood donors or fresh blood for transfusion purposes through its 'Walking Blood Bank' dubbed as 'Blood Hounding' which was renamed to 'Blood Hound Gang' that was formally launched in 2001.

It has and will continually serve humanity and alleviate human suffering whenever and wherever it may be found with the help coming from the Red Cross Youth of UPLB Alumni.