Interesting Will, thanks.
I do think the AGE theory has some relevance but I would attribute this to the decreased ability of FMS/CFS patients to metabolize carbohydrates. It is hard to
find FMS/CFS patients who do not suffer from adrenal exhaustion. Adrenal depletion results in faulty carb metabolism. The adrenals are involved in protein and fat metabolism as well.
How are you finding the pulses to be in the Kidney positions?
I think that most people/sufferers who have studied this syndrome...not disease...would agree that not much headway would be made without
recognizing that it is a neuroendocrine disorder. I would not refer my patients to Rheumatologist but rather to an Endocrinologist.
While there may be some symptoms fitting to the field of Rheumatology, there are way too many concurrent problems to
relegate its causes to this field. Perhaps that's not your contention, anyway. Fortunately, as usual, TCM does much to help just by correct pattern dx. And....of course, a large part of the equation is getting the patient to do what it takes to recover their adrenals and maintain a lifestyle that would continue to care for and spare unnecessary adrenal expenditure. Once exhausted they are not fully recoverable.
I also see the inflammatory response as being a result of the aformentioned carb problem and probably a Western diet in general....high temp cooked foods and processed foods.....also leading to poor digestion and possibly Leaky Gut Sydrome. ....Spleen and Stomach problems... Gosh, problems across all Organ systems.... BTW: One of the most important actions of the adrenal glucocorticoids(steroid hormones) is on the inflammatory response. The drug companies have this well-pegged and are making billions. Pharmaceutical steroids further damage healthy adrenals.
Here are S & S for Adrenal Exhaustion
Compared to FMS checklist:
BTW: AGE's are affected by food restriction.
Here's more on the neuroendocrine theory.
Adrenal Chapter from "Body Mechanics" (long but easy to skip around)
I find this point very interesting ...esp. considering that FMS can be "inherited". (Hmmm, and maybe postpartum sydrome in some women...just a theory)
"10) The stress of pregnancy can aggravate a case of hypoadrenia. This can cause problems in the fetus. In the third trimester when the fetus starts producing its own adrenal hormones the mother, if she suffers from hypoadrenia, not having enough of her own will "rob" some of the fetus. The mother as a result will feel better until after she gives birth and she loses the extra hormone supply. Meanwhile, the fetus’ adrenals being forced to produce enough hormones for it and an adult will get quickly depleted. The excess hormone production will also depress its immune system. The infant will become very prone to having allergies, recurrent infections, and be very irritable."
Fetal adrenal hormones are responsible for it's lung development.
I did mention pulses somewhere in there didn't I? ;-)
Kit Curtin
AOMA
----- Original Message -----From: WMorris116@...Sent: Tuesday, February 28, 2006 5:44 AMSubject: [PulseDiagnosis] fibromyalgia and advanced glycation end-product-modified proteinsAre advanced glycation end-product-modified proteins of pathogenetic importance
in fibromyalgia?
http://rheumatology.oxfordjournals.org/cgi/content/full/41/10/1163?eaf
And, this would seem to predispose towards a 'cotton' pulse.Will