Hi Group -
Tawny's post reminded me of the following -
I wanted to pass this article along to you so that you can try this if you
like. I am using CERTO along with Cherry or Pomegranate concentrate or
extract with a teaspoon of raw honey in a glass of club soda and having
great results immediately. It is keeping the pain and inflammation down
considerably. I don't know if it is a cure, but I am certainly hoping it
will at least repair some of the damage that has been done. At the same
time, I am also doing what is known as The Beck Protocol, so between the two
protocols, I am looking forward to some long term results.

Sasha

Subject: Life Extension Update October 4 2005

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October 4, 2005
In this issue
Life Extension Update Exclusive
Plant compounds could prevent joint inflammation
What's Hot
Pomegranate extract helps protect against arthritis
Protocol
Arthritis
Featured Products
ArthroPro System
Chloroplex


Life Extension Update Exclusive
Plant compounds could prevent joint inflammation
Research reported in the September 27 2005 issue of the Proceedings of the
National Academy of Sciences (http://www.pnas.org/) revealed that compounds
found in cruciferous vegetables could help protect the joints from damaging
inflammation, which may lead to a new treatment for arthritis.
The current experiment resulted from the interest of researchers at Johns
Hopkins University concerning the differing effects that shear stress has on
blood vessels and joints. Shear stress is generated when liquids move across
surfaces, which in this case are the cells lining the blood vessels and the
joints. Blood vessels produce beneficial phase 2 enzymes that help protect
cells from carcinogens in response to shear stress, but in the joints high
shear stress increases cyclooxygenase 2 (COX-2) enzyme levels, resulting in
pain, inflammation and suppression of phase 2 enzymes, and the eventual
death of cartilage cells known as chondrocytes.
To find out what would happen when chondrocytes were first exposed to phase
2 enzymes, the Hopkins researchers, led by associate professor of chemical
and biomolecular engineering Konstantinos Konstantopoulos, exposed cultured
chondrocytes to compounds derived from cruciferous vegetables such as
broccoli that are known to increase the enzymes. After 24 hours, the
researchers subjected the cells to a stress test designed to mimic the
effects of exercise, which would normally produce an increase in COX-2. Lead
author Zachary R. Healy, who is a doctoral student in Dr Konstantopoulos'
laboratory, explained the findings: “The beneficial phase 2 enzymes somehow
seemed to prevent the activation of the inflammatory COX-2 enzyme. The phase
2 enzymes inhibited the inflammation and the apoptosis -- the cellular
suicide we'd observed."
Paul Talalay, who is a coauthor of the PNAS report, commented, "This was the
first work done in applying these phytochemicals to chondrocytes, which are
constantly under the influence of forces because of the way we move our
joints. The phase 2 inducers seemed to counteract the effects of that stress
by inhibiting the expression of COX-2 enzyme. It's interesting to think that
people may be able to obtain this benefit through dietary components."

What's Hot
Pomegranate extract helps protect against arthritis
The September 2005 Journal of Nutrition (http://www.nutrition.org/)
published the findings of Case Western Reserve University School of Medicine
researchers that an extract derived from pomegranate fruit can block enzymes
that contribute to osteoarthritis. The study is the first to show the
ability of the fruit to slow cartilage deterioration.
http://www.lef.org/whatshot/index.html#pehp

Protocol
Arthritis
The word arthritis literally means inflammation of the joint. Joints can
become inflamed for many reasons, but most of us think of arthritis usually
as one of two kinds: osteoarthritis or rheumatoid arthritis. These are two
very distinct entities, and they are both a huge source of discomfort and
disability. A significant amount of new research provides an understanding
of both kinds of arthritis so that those who are afflicted may find relief.
Inflammation is partially characterized by high levels of arachidonic acid
products which are metabolized along two different enzymatic pathways:
cyclooxygenase (COX) and lipoxygenase, leading to prostaglandin (PGE-2) and
leukotriene (LTB4). Some physicians believe these are the most important
mediators of inflammation (Srivastava et al. 1992). PGE2 and LTB4 play a
crucial role in arthritis by causing resorption of bone, stimulating the
secretion of collagen breakdown enzymes, and inhibiting the formation of
proteoglycans--the building blocks of cartilage.
Unlike toxic FDA-approved drugs, natural therapies and diet modification can
often provide relief from chronic inflammation and pain. One of the most
compelling reasons for using natural therapies in arthritic conditions is
that while some drugs can cause cartilage destruction, natural therapies
correct the underlying factors involved in arthritic cartilage degeneration.
Natural therapies have been shown to work by the following mechanisms:
Inhibiting COX-2
Inhibition of the 5-LOX pathway
Suppressing TNF-alpha , IL -1b, and IL-6
Reducing production of LTB4
Preventing the over - expression of NF-KB
Inhibiting the formation of PE2
Promoting the synthesis of proteoglycans and glycosaminoglycans in the
joints
Suppressing cartilage-destroying enzymes, collagenase and phospholipase
Attracting water to the cartilage to enhance synovial lubrication
http://www.lef.org/protocols/prtcl-013.shtml

Featured Products
ArthroPro System

The ArthroPro multinutrient formula:
Promotes prostaglandin pathways that limit the production of TNF-a and IL-1b
through its super concentrated nettle leaf extract ingredient.
Inhibits 5-LOX with the inclusion of inflammatory blocker 5-Loxin®.
Protects against the age-related damaging effects of the COX-2 enzyme with
the agent Nexrutine®.
Includes gingerols (from ginger powder extract), which restrain the
cyclooxygenase and lipoxygenase cascade and the production of thromboxane
and leukotriene, powerful triggers of pain.
Helps to maintain healthy joint cartilage with the addition of glucosamine
and chondroitin sulfate, which also controls collagenase and phospholipase
http://www.lef.org/newshop/items/item00620.html
Chloroplex capsules

Chloroplex contains a variety of carotenoids and other plant extracts that
can protect against DNA mutation and enhance cardiovascular and ocular
health. Chloroplex also contains chlorophyll, an antioxidant and DNA
protectant. In addition, chlorophyll has the ability to neutralize
aflatoxins, produced by the Aspergillus flavus mold that grows on corn and
peanuts. While vitamin A and beta-carotene can neutralize aflatoxins to some
degree, chlorophyll is much more effective.
http://www.lef.org/newshop/items/item00178.html


If you have questions or comments concerning this issue or past issues of
Life Extension Update, send them to ddye@... or call 954 202
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For longer life,
Dayna Dye
Editor, Life Extension Update
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-------Original Message-------

From: Tawny J Northern
Date: 10/05/05 01:55:21
To: Psoriatic-Arthritis@yahoogroups.com
Subject: [Psoriatic-Arthritis] Re: Why Cherry Juice works (Cheryl)

Hi Cheryl, Thanks for this article. I've heard about Cherry Juice
but not why it works before. Sincerely Tawny
-- In Psoriatic-Arthritis@yahoogroups.com, Cheryl
<purplesun0104@y...> wrote:
> Hi,
> A lot of people are interesed in Cherry Juice for their aches and
pains and general good health, here is some research information I
thought would be of interest:
>




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