I noticed a HUGE improvement with my fatigue shortly after a started
taking the Enbrel. I remember one Saturday morning/afternoon a few
weeks after I started taking it, being able to run more than one
errand and not having to go home to rest. I still have pain
everyday, but that is because I haven't had quite the response I
should be getting the Methotrexate. None-the-less...I am sure you
will see great improvements with the addition of the Enbrel to your
regimine. My Dr. believes in dual therapy, thus I am on both Metho
and Enbrel. Where one may lack, the other could pick up. I agree
and think dual therapy is worth it!

The other thing you may want to think about is whether to take the
25mg injections twice per week OR the 50mg injections once per
week. They just recently started offering the latter. This is what
I know about the two.

I take the 25mg inj and do pretty well. I CANNOT take them in the
morning...I get very dizzy when I do that. But for some reason,
when I take them in the evening I do fine. Once in awhile, I get a
dizzy spell but it only lasts a few minutes or so. Not a big deal.
I will take the occasional dizzy spell for ENERGY! :-)

I have heard the 50mg inj hurt more when they are administered...a
lot more. That is about all I have heard. I am not clear as to why
it would hurt more, but that is what people have said.

Hope this helps!

~Karin


--- In Psoriatic-Arthritis@yahoogroups.com, "Pete and Pen"
<PETERMIDGLEY@s...> wrote:
> Thank you so much for the info on Enbrel. It sounds like I have a
similar condition to your husband which is worse PA than skin PA.
> I will be starting my Enbrel this week. I have received my
starter kit and waiting for a nurse to call me. I look forward to
it. Are there any side affects that you know of?
> Cheers
>
> ----- Original Message -----
> From: Joan Goldstein
> To: Psoriatic-Arthritis@yahoogroups.com
> Sent: Monday, November 01, 2004 9:49 AM
> Subject: Re: [Psoriatic-Arthritis] Enbrel information
>
>
> Everyone has different experiences, and my husband's
> Enbrel experience is terrific. He has a slight case
> of skin P, and a disfiguring case of PA. He takes
> Enbrel shots twice a week, and it is controlling his
> PA to the point that he almost feels it is gone.
>
> My understanding of Enbrel, from our Rhuematologist as
> well as from our family experience, is that it takes a
> much higher dose to aleviate the skin plaques than it
> does to control the Arthritis. I believe that this is
> so: My husband's sister has a severe case of skin P,
> and a lesser case of PA, the exact opposite of my
> husband. His sister takes twice as much Enbrel for
> her skin as my husband does for his arthritis.
>
> By the way, my husband was on MTX and Vioxx for quite
> a while before switching to Enbrel. The Enbrel is a
> much better solution for him. He takes no other meds
> for his PA now. He has been on it long enough that
> the Dr tried to reduce the dose - the reduced dose
> didn't work as well, so he is back to twice a week.
>
> Good luck - Enbrel is great when it works for you!
>
>
>
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