Hi everyone,
I came across this article to share with any of you
out there who are dealing with IBS clients or
patients.

Seth-Deborah


Abuse History Affects Pain Regulation In Women With
Irritable Bowel Syndrome
UCLA and University of North Carolina researchers
have found that women with irritable bowel syndrome
(IBS) who have experienced sexual and/or physical
abuse may have a heightened brain response to pain
that makes them more sensitive to abdominal
discomfort. IBS is a condition that affects 10 to 15
percent of the population and causes gastrointestinal
discomfort along with diarrhea, constipation or both.

Researchers used brain imaging to show that patients
with IBS who also had a background of abuse were not
as able to turn off a pain modulation mechanism in the
brain as effectively as were IBS patients who had not
suffered abuse.

According to previous studies, more than 50 percent of
patients with IBS have been physically or sexually
abused at some time in their lives. The new finding
may help explain why those in this subset of IBS
patients experience greater pain and poorer health
outcomes than others with the disorder.

Such insight provides a greater understanding of how
the disorder develops and may offer new pathways for
treatment. Brain imaging studies were performed at the
UCLA Brain Mapping Center.

The research appears in the Feb. 1 online edition of
the journal Gastroenterology. Authors include Dr.
Emeran Mayer, professor of medicine, David Geffen
School of Medicine at UCLA; Dr. Douglas Drossman,
professor of medicine, and Dr. Yehuda Ringel, lead
study author and assistant professor of medicine, both
at the University of North Carolina at Chapel Hill.

The study was funded by the National Institutes of
Health (NIDDK and NCCAM).

Adapted from materials provided by University of
California - Los Angeles.



University of California - Los Angeles (2008, February
3). Abuse History Affects Pain Regulation In Women
With Irritable Bowel Syndrome

<DIV><FONT color=#6000bf>Seth-Deborah Roth RN,CRNA,NBCCH, CI,   <FONT
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