Post-Doc Openings @ Mayo : Genomics, Neph, HTN, Molecular, Biochem,
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Postdoctoral Position - Genomics
Summary
Investigator: David Smith, Ph.D. Professor and Consultant
We are looking for a highly trained individual with experience in both advanced molecular biology techniques and pathology to work on a project aimed at utilizing Next Generation DNA sequencing to measure gene expression in individuals who differ in their immune response to various vaccines. Ability to work with new technologies involved in library preparation for Next Generation sequencing. Will construct several hundred transcriptome libraries in preparation for DNA sequencing on the Illumina Genome Analyzer.
How to apply
Applications, including curriculum vitae and bibliography, summary of past accomplishments, and the names and email addresses of three references, should be sent to:
David Smith Ph.D. Mayo Clinic in Minnesota 200 First Street SW Rochester, MN U.S.A. 55905
Phone Number: 507 266-0309
Postdoctoral Position - Division of Nephrology and Hypertension
Summary
Investigator: Karl Nath, MD Professor of Medicine
Postdoctoral position available immediately to study the pathophysiology of kidney and vascular diseases. Dr Nath's laboratory has special interests in the study of acute renal failure, heme oxygenase, vascular access dysfunction, and sickle cell disease, employing rodent disease models and a broad range of analysis techniques. Applicant should have experience with animal experimentation and preferably have some experience with biochemical and molecular analysis techniques. Candidate should also possess strong communication and writing skills.
How to apply
Applications, including curriculum vitae and bibliography, summary of past accomplishments, and the names and email addresses of three references, should be sent to:
Anthony Croatt Mayo Clinic in Minnesota 200 First Street SW Rochester, MN U.S.A. 55905
Postdoctoral Position - Department of Molecular Medicine
Summary
Investigator: Kah-Whye Peng, Ph.D. Associate Professor
Motivated individuals with experience in molecular virology and tumor angiogenesis are invited to join the group of Dr. Kah-Whye Peng to develop replication-competent oncolytic measles viruses for cancer therapy with particular emphasis on retargeting virus tropism to tumor neovasculature.
How to apply
Applications, including curriculum vitae and bibliography, summary of past accomplishments, and the names and email addresses of three references, should be sent to peng.kah@... Kah-Whye Peng, Ph.D. Dept of Molecular Medicine, Gugg 18 Mayo Clinic 200 First Street SW Rochester, MN U.S.A. 55905
Kah-Whye Peng Ph.D. Mayo Clinic in Minnesota 200 First Street SW Rochester, MN U.S.A. 55905
Phone Number: 507-284-8357
Postdoctoral Position - Biochemistry and Molecular Biology Program
Summary
Investigator: Kun Ling, Ph.D.
One postdocs position is open for a newly established laboratory. We are interested in the molecular mechanism underlying cell adhesion and migration, and how these would relate to embryogenesis, wound healing, and human diseases such as cancer metastasis. Our current major focus is to investigate how type I phosphatidylinositol phosphate kinases (PIPKIs), which generate phosphatidylinositol-4,5-bisphosphate, regulate cell adhesion and migration, and participates in the relevant life events. Multidisciplinary approaches including molecular biology, biochemistry, cell biology, and genetics are used to address our research objectives. The postdoctoral fellow will join several ongoing projects to define the roles of PIPKIs in cancer metastasis, angiogenesis, and wound healing.
Ph.D. degree in cell biology or biochemistry is required. Candidates with experience of knockout or transgenic mouse will be preferred.
How to apply
Applications, including curriculum vitae and bibliography, summary of past accomplishments, and the names and email addresses of three references, should be sent to:
Kun Ling Mayo Clinic in Minnesota 200 First Street SW Rochester, MN U.S.A. 55905
Phone Number: 507-293-3498
Postdoctoral Position - Department of Molecular Pharmacology and Experimental Therapeutics
Summary
Investigator: Richard Weinshilboum, M.D. Professor
A Postdoctoral Research Fellow is sought by the Mayo Pharmacogenomics Research laboratory for a position that is available immediately. This laboratory is associated with the Mayo-NIH Pharmacogenetics Research Network (PGRN), a nationwide network of research programs devoted to pharmacogenetic and pharmacogenomic research. Studies conducted include the use of high throughput resequencing of genes that might influence drug response, functional genomic, in depth mechanistic studies of the functional effects of DNA sequence variation and translational studies of the implications of variant polymorphisms and haplotypes for individual differences in drug response. Requirements for the position include a Ph.D. and/or M.D. degree with significant past laboratory research experience ? with an emphasis on the techniques of molecular genomics.
How to apply
Applications, including curriculum vitae and bibliography, summary of past accomplishments, and three signed reference letters, should be sent to Dr. Richard Weinshilboum.
Richard Weinshilboum M.D. Mayo Clinic in Minnesota 200 First Street SW Rochester, MN U.S.A. 55905
Postdoctoral Position - Department of Biochemistry and Molecular Biology
Summary
Investigator: Irina Kovtun, PhD Assistant Professor
A Postdoctoral Research position is available to study the molecular mechanism of triplet repeat instability in embryonic stem cells. We are interested in cell cycle control of repeat expansion in mammalian cells. A Ph.D. in molecular biology or biochemistry is required. A background in developmental biology and familiarity with the techniques (isolation of blastomeres, primary cell isolation and culture) are desirable. Candidates who are highly self-motivated in research are encouraged to apply.
How to apply
Applications, including curriculum vitae and bibliography, summary of past accomplishments, and the names and email addresses of three references, should be sent to: Irina Kovtun, Assistant Professor, Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic College of Medicine, 200 First Street SW, Rochester, MN USA. 55905. Email: kovtun.irina@...
Irina Kovtun Ph.D. Mayo Clinic in Minnesota 200 First Street SW Rochester, MN U.S.A. 55905
Phone Number: 284-8911 or 284-3206
Postdoctoral Position - Division of Epidemiology
Summary
Investigator: Gloria M. Petersen, Ph.D. Professor of Epidemiology
Mayo Clinic in Rochester, Minnesota announces new postdoctoral positions in cancer genetics/cancer genetic epidemiology. Positions will be funded by the Mayo Cancer Genetic Epidemiology Training Program, which is supported by a grant from the National Cancer Institute, and are 3 years in duration. Mentoring will be provided by experienced faculty, including cancer genetic epidemiologists, statistical geneticists, cancer geneticists, bioinformaticians and clinical mentors. The goal of this training program is to develop a new cadre of scientists capable of combining laboratory based genetics and observational epidemiologic methods for developing independent careers that address cancer-related health issues, including prevention, detection, therapy and control. In addition to a stipend, the trainee will receive $15,000 per year for supplies. U.S. citizens or permanent residents only.
Located 80 miles southeast of the Minneapolis-St. Paul metro area, the Mayo Clinic is well regarded for its cancer research which includes established resources such as the Rochester Epidemiology Project, and SPOREs in Prostate, Breast and Pancreatic cancers, Brain tumors and Lymphoma and Myeloma. The NCI designated comprehensive Mayo Clinic Cancer Center (MCCC) provides extensive infrastructure support for patient orientated research, including biostatistical support and shared analytical resources supporting population science, and well-equipped laboratories and cores. Please visit http://mayoresearch.mayo.edu/mayo/research/cancercenter/ and
http://www.mayo.edu/ for more information.
How to apply
Mayo offers an attractive benefit package. Salary is competitive, and will be determined by experience. Please send statement of interest and accomplishments, CV, and the names of three references too: Gloria M. Petersen, Ph.D. Director, Cancer Genetic Epidemiology Training Program Mayo Clinic 200 First Street SW Rochester, MN 55905 Phone: (507)284-2896 Fax (507) 266-2478 E-mail: schuh.melissa@...
Melissa Schuh Mayo Clinic in Minnesota 200 First Street SW Rochester, MN U.S.A. 55905
Phone Number: 507-284-2896
Postdoctoral Position - Division of Hematology Research
Summary
Investigator: A. Keith Stewart, MD Professor of Medicine
A post-doctoral research position in B-cell malignancy and high throughput RNAi screening is available immediately at the Mayo Clinic Arizona Cancer Center. Genome wide RNAi screens of myeloma cells in the presence or absence of chemotherapies have revealed multiple vulnerabilities in myeloma cells. Follow up studies of these RNAi identified hits are required. Excellent writing skills are mandatory. Experience with bio-analysis of large genome based data sets, familiarity with molecular biology tools, including viral vector systems and with B-cell biology would all be assets.
How to apply
Applications, including curriculum vitae and bibliography, summary of past accomplishments, and the names and email addresses of three references, should be sent to:
Linda Farquhar Mayo Clinic in Minnesota 200 First Street SW Rochester, MN U.S.A. 55905
Phone Number: 480-301-4279
Postdoctoral Position - Biochemistry and Molecular Biology Program
Summary
Investigator: Zhiguo Zhang, Ph.D. Assistant Professor
Postdoctoral positions are available to study regulation of genome stability by histone modifying enzymes in yeast and/or epigenetic silencing of tumor suppressor genes in mammalian cells. Please visit (http://ndc.mayo.edu/mayo/research/zhang_lab/) for current projects in the lab. Candidates who have solid background in molecular biology and biochemistry and are highly self-motivated in research are encouraged to apply. Experiences with mammalian cells or yeast are very important for the postdoctoral positions. Salary will be paid according to the NIH guidelines. In addition, Mayo Clinic offers a comprehensive benefit package.
How to apply
Applications, including curriculum vitae and bibliography, summary of past accomplishments, and the names and email addresses of three references, should be sent to:
Zhiguo Zhang Mayo Clinic in Minnesota 200 First Street SW Rochester, MN U.S.A. 55905
Postdoctoral Position - Bioinformatics
Summary
Investigator: Jean-Pierre Kocher, Ph.D. Assistant Professor
POSTDOC POSITION NEXT-GENERATION SEQUENCING DATA ANALYSIS
Mayo Clinic in Rochester, Minnesota is seeking postdoc candidates in methodology development and annotation of DNA sequence data from high throughput, next-generation sequencing machines (e.g. Roche/454, Illumina/Solexa, ABI SOLiD).
Applicants must hold a Ph.D. degree in Bioinformatics, or related fields, having a solid background in developing bioinformatics tools, and with enough knowledge of molecular genetics. Experience with analysis of next generation sequencing data (454, Solexa, SOLiD) is a plus. Candidates must have strong communication skills and the ability to work in a team environment.
The postdoc is expected to lead the development of high-performance sequence data analysis pipeline, collaborate with sequencing core labs, experimental collaborators and colleagues at sequencing machine manufacturing companies. The examples of research areas are: rare mutation detection in somatic cancer samples, transcriptome profiling using 3?-tag sequencing and RNA-SEQ, and de novo assembly.
About the Division of Biomedical Statics and Informatics (BSI)
The Division of Biomedical Statics and Informatics includes more than 280 experts in biostatics, bioinformatics, and clinical informatics. Our scientists work collaboratively with basic and clinical researcher, providing analytical and interpretative expertise to enable or validate discoveries with high impact on patient care. BSI also leads the development of statistical and informatics methodologies to provide novel approaches to mine and analyze biomedical data.
Postdoctoral Position - Bioinformatics
Summary
Investigator: Jean-Pierre Kocher, Ph.D. Assistant Professor
The division of Biomedical Statistics and Informatics is recruiting a bioinformatics postdoctoral fellow. The successful individual will join the bioinformatics team to work on the analysis of multiple large genomics data sets. The fellow will join the BORA development team (Biologically Oriented Repository Architecture) to apply and develop system biology methods to large datasets made up of several data types such as clinical data, gene expression, genotypes, resequencing data, microRNA expression, methylation status, metabolomics, next generation sequencing, and bioinformatics annotation. The initial focus of this position will be to work on datasets from cancer and other complex diseases. This project requires to work in a team environment in close collaborations with clinicians, researchers, bioinformatics colleagues, information technology professionals, and statisticians.
About the Division of Biomedical Statics and Informatics (BSI)
The Division of Biomedical Statics and Informatics includes more than 280 experts in biostatics, bioinformatics, and clinical informatics. Our scientists work collaboratively with basic and clinical researcher, providing analytical and interpretative expertise to enable or validate discoveries with high impact on patient care. BSI also leads the development of statistical and informatics methodologies to provide novel approaches to mine and analyze biomedical data.
Minimum Education and/or Experience Required:
The candidate is required to have knowledge of human molecular biology and doctoral level experience with statistical analysis of biological data. The ideal candidate would have a PhD in bioinformatics, but equivalent combinations of experience and education will also be acceptable: Either a PhD in biological sciences with experience with data analysis of bioinformatics data or a PhD in a statistical or computational field with experience analyzing biological data.
Additional Experience and/or Qualifications:
The successful candidate will have experience with data analysis of genomics data types not limited to sequence analysis as well as possess a functional knowledge of univariate statistics, multivariate statistics, and linear models. The ideal candidate will also be expected to have some familiarity with Bayesian Statistics or machine learning techniques.
The fellow must be proficient in at least one programming or scripting language (such as Java,Perl, python, or ruby) or one statistical programming language such as R/S-plus or SAS. Experience with SQL and other informatics computing and data management technologies is desirable.
Good written and oral communication skills are required as well as the ability to prioritize, organize, and delegate various tasks on projects. The ideal candidate will have a history of demonstrated initiative in administration, education (seminars, training), software development, and technical reports.
How to apply
Applications, including curriculum vitae and bibliography, summary of past accomplishments, and the names and email addresses of three references, should be sent to: (When submitting materials please reference
Dawn Bergen Mayo Clinic in Minnesota 200 First Street SW Rochester, MN U.S.A. 55905
Phone Number: 507-284-5541
Postdoctoral Position - Division of Cardiovascular Diseases
Summary
Investigator: Petras Dzeja, Ph.D. Associate Professor
A postdoctoral research position is available immediately in cardiovascular bioenergetics, metabolomics and metabolic signaling area. A Ph.D. in biological sciences and a strong background and interest in biochemistry, cell bioenergetics and metabolic signaling are required. Familiarity with HPLC, GC/LC/MS, NMR, metabolic labeling and computational methods is a plus.
How to apply
Applications, including curriculum vitae and bibliography, summary of past accomplishments, and the names and email addresses of three references, should be sent to: Petras Dzeja, PhD, E-mail: Dzeja.Petras@...
Petras Dzeja Mayo Clinic in Minnesota 200 First Street SW Rochester, MN U.S.A. 55905
Postdoctoral Position - Oncology
Summary
Investigator: Zhenkun Lou, Ph.D.
A postdoctoral fellow position is available to study the molecular mechanism of aging and cancer. We are interested in the DNA damage response pathway, which is important for maintaining genomic stability and tumor suppression (Nature 421:957-961, 2003; Nature Structure and Molecular Biology, 12:589-563, 2005; Molecular Cell, 21:201-14. 2006). In addition, we are interested in the regulation of protein deaetylase SirT1 and its implication in aging and cancer (Nature, 451: 583-6, 2008).
Applications, including curriculum vitae and summary of past accomplishments, and the names and email addresses of three references, should be sent to: Zhenkun Lou, PhD, Assistant Professor, Department of Oncology, Mayo Clinic College of Medicine, 200 First Street SW, Rochester, MN U.S.A. 55905. Email: lou.zhenkun@...
How to apply
Applications, including curriculum vitae and bibliography, summary of past accomplishments, and the names and email addresses of three references, should be sent to:
Zhenkun Lou Mayo Clinic in Minnesota 200 First Street SW Rochester, MN U.S.A. 55905
Postdoctoral Position - Division of Hematology Research
Summary
Investigator: Angela Dispenzieri, M.D. Professor of Laboratory Med/Pathology and Medicine,
Research Associate
In this position a self-directed researcher will design and implement translational research studies in Hematology, relating to B-Cell Malignancies, dissecting POEMS and Castleman?s disease. The researcher will determine the experiment progression, and analyze the results, as well as write manuscripts for publication and presentation at national and international meetings. Requires Ph.D. in Biology or related field; 3 years post-doctoral experience in Molecular and Cell Biology, which must include expression cloning in multiple mammalian systems; and multiple first-author publications.
How to apply
Applications, including curriculum vitae and bibliography, summary of past accomplishments, and the names and email addresses of three references, should be sent to:
Angela Dispenzieri M.D. Mayo Clinic in Minnesota 200 First Street SW Rochester, MN U.S.A. 55905
Phone Number: 4-3149
Postdoctoral Position - Department of Molecular Medicine
Summary
Investigator: Yasuhiro Ikeda, Ph.D., D.V.M. Assistant professor
Postdoctoral position available immediately to study induced pluripotent stem (iPS) cells for clinical interventions. Dr Ikeda's laboratory has special interests in iPS-mediated gene and cell therapy for type 1 diabetes and hemophilia. Applicant should have experience with cell culture and animal experimentation and preferably have some experience with viral vector techniques or stem cells. Candidate should also possess strong communication and writing skills.
How to apply
Applications, including curriculum vitae and bibliography, summary of past accomplishments, and the names and email addresses of three references, should be sent to: ikeda.yasuhiro@...
Yasuhiro Ikeda Ph.D., D.V.M. Mayo Clinic in Minnesota 200 First Street SW Rochester, MN U.S.A. 55905
Phone Number: 507-538-0153
Postdoctoral Position - Department of Molecular Pharmacology and Experimental Therapeutics
Summary
Investigator: Liewei Wang, M.D., Ph.D. Assistant Professor
A postdoctoral Research Fellow is sought by a Pharmacogenomics laboratory for a position that is available as soon as possible. This laboratory will focus on the pharmacogenomics of drug targets, especially those anti-neoplastic agents. Studies conducted include the use of high throughput genotyping and expression microarrays that might influence drug response, functional genomic, in depth mechanistic studies of the functional effects of DNA sequence variation and translational studies of the implications of variant polymorphisms and haplotypes for individual differences in drug response. Requirement for the position include a Ph.D. and /or M.D. degree with significant past laboratory research experience with an emphasis on cancer genetics and cancer pharmacology.
How to apply
Applications, including curriculum vitae and bibliography, summary of past accomplishments, and 3 signed reference letters, should be sent to: Liewei Wang M.D., PhD. Mayo Clinic College of Medicine Department of Molecular Pharmacology and Experimental Therapeutics 200 First Street SW Rochester, MN U.S.A. 55905 Email: wang.liewei@...
Liewei Wang M.D., Ph.D. Mayo Clinic in Minnesota 200 First Street SW Rochester, MN U.S.A. 55905
Postdoctoral Position - Clinical Pharmacology Clinical Pharmacology Fellowship Training
Summary
Investigator: Richard Weinshilboum, M.D. Professor
Mayo Clinic in Rochester, MN is seeking candidates for NIH-funded Clinical Pharmacology Fellowship positions. These positions are open to US citizens or permanent residents with M.D., M.D.-Ph.D., DO or equivalent degrees - especially those who have already completed residency training and who wish fellowship research training in clinical pharmacology, with an emphasis on the application of pharmacogenomics, pharmacometabolomics and molecular techniques to clinical pharmacology and related fields.
To learn more about Mayo Clinic and Rochester, MN please visit
www.mayoclinic.org
Mayo Clinic is a not-for-profit organization with integrated research, education and clinical practice activities on a multi-campus environment.
Mayo Foundation is an affirmative action and equal opportunity employer and educator.
How to apply
CV and bibliography, summary of past accomplishments, and three signed letters of recommendation should be sent to: Richard Weinshilboum, M.D. Department: Molecular Pharmacology and Experimental Therapeutics Division: Clinical Pharmacology Mayo Clinic 200 First Street SW Rochester, MN 55905 Email address: Weinshilboum.Richard@...
Richard Weinshilboum M.D. Mayo Clinic in Minnesota 200 First Street SW Rochester, MN U.S.A. 55905
Postdoctoral Position - Division of Nephrology and Hypertension
Summary
Investigator: John Lieske, M.D. Professor of Medicine
Applications are sought for a postdoctoral fellow to participate in a study of urinary proteomics in relationship to kidney stone disease. Protocols will be developed and implemented to identify novel inhibitors of urinary crystallization and stone formation.
How to apply
Applications, including curriculum vitae and bibliography, summary of past accomplishments, and the names and email addresses of three references, should be sent to: John C. Lieske, MD Lieske.John@...
John Lieske M.D. Mayo Clinic in Minnesota 200 First Street SW Rochester, MN U.S.A. 55905
Phone Number: 507-284-2064
Postdoctoral Position - Biochemistry and Molecular Biology Program
Summary
Investigator: Georges Mer, Ph.D.
A postdoctoral position in X-ray crystallography is available immediately to study protein complexes involved in DNA repair and cell cycle checkpoint signaling. Candidates should have a doctoral degree with demonstrated experience in macromolecular crystallography and protein biochemistry.
http://mayoresearch.mayo.edu/mayo/research/staff/mer_g.cfm
How to apply
Applications, including curriculum vitae and the names and email addresses of three references, should be sent to:
Georges Mer Ph.D. Mayo Clinic in Minnesota 200 First Street SW Rochester, MN U.S.A. 55905
Postdoctoral Position - Department of Molecular Pharmacology and Experimental Therapeutics
Summary
Investigator: Doo-Sup Choi, Ph.D. Assistant Professor
A postdoctoral position is available immediately to study neurobiology of alcoholism and drug addiction, funded by NIH and the SC Johnson Foundation at Mayo Clinic College of Medicine. Our laboratory focuses on the integrated neural system of addictive behaviors in state-of-the-art facilities. The individual will have the opportunity to work with genetically engineered rodent models (e.g. Nature Neurosci. 7, 855-86, 2004; PNAS 21, 8215-8220, 2006; Genes, Brain and Behav, 6, 776-783, 2007). Qualifications for this position are, PhD or MD/PhD degree with 0-2 year postdoctoral experience in molecular biology, mouse genetics, neurobiology, or receptor pharmacology. Experience in alcohol-related rodent behavior and brain histology is preferred.
How to apply
Applications, including curriculum vitae and bibliography, summary of past accomplishments, and the names and email addresses of three references, should be sent to: Doo-Sup Choi, Ph.D. Mayo Clinic College of Medicine, Molecular Pharmacology and Experimental Therapeutics, Molecular Neuroscience Program, 200, First Street SW, Rochester MN 55905, email:choids@...
Doo-Sup Choi Ph.D. Mayo Clinic in Minnesota 200 First Street SW Rochester, MN U.S.A. 55905
Phone Number: 507-284-5602
Postdoctoral Position - Division of Experimental Pathology
Summary
Investigator: Fergus Couch, Ph.D. Associate Professor of Laboratory Medicine and Pathology
A postdoctoral position is available to investigate how disruption of cell division contributes to cancer. Candidates should have a strong background in molecular biology and cellular biology and experience with mouse models.
How to apply
Applications, including curriculum vitae and bibliography, summary of past accomplishments, and the names and email addresses of three references, should be sent to:
Fergus Couch Mayo Clinic in Minnesota 200 First Street SW Rochester, MN U.S.A. 55905
Phone Number: 6-0878
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