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Does NHE promote diabetes?

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Message #191 of 429 |

Growth Hormone seems to promote diabetes in two ways:
1) by GH's ability to increase free fatty acid concentration in the blood
following lipolysis
(acts directly on beta cells in pancreas?)
2) by a sort of negative feedback loop which downregulates insulin receptors
(because GH
utilizes parts of the insulin signalling pathway)

Please bring relief to my concerns. Does NHE promote diabetes?

Thu Aug 31, 2006 12:36 am

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Message #191 of 429 |

Expand Messages	Author	Sort by Date
Growth Hormone seems to promote diabetes in two ways: 1) by GH's ability to increase free fatty acid concentration in the blood following lipolysis (acts...	fueled_on_ascorbate fueled_on_as...	Aug 31, 2006 12:36 am
Welcome to the board! First off, you should understand that growth hormone is a problem only when its too low or too high in an individual. There's some really...	Joel Rosart jrosart295	Aug 31, 2006 1:21 am
Doesn't NHE prevent diabetes? I kind of thought that since NHE keeps insulin levels low most of the time, that it would be the opposite. Preventing type II ...	Jason javidyana	Aug 31, 2006 2:17 am
Jason, I agree NHE should prevent diabetes. I believe concern arose from the fact that: a) NHE strives to heighten GH production b) Excess GH production can...	Joel Rosart jrosart295	Aug 31, 2006 2:28 am
Thanks Joel, I wouldn't imagine that any dietary manipulation would make GH go unreasonably hog wild. I knew a few people who were using exogenous GH, the...	jason yana javidyana	Aug 31, 2006 2:51 am
Not off topic at all Jason, this is what NHE is all about! Unless you're willing to take GH for the rest of your life I think there's no point in taking it....	Joel Rosart jrosart295	Aug 31, 2006 3:08 am
To add to Joel's good comments: Regarding aging and growth hormone, it appears that it isn't the body's capacity to produce the hormone that declines. Rather...	Simon Dankel simon_dankel	Aug 31, 2006 10:52 am
Good points Simon. The more you look into hormomes, the more complicated you realize the whole system is. It seems like influencing someone's hormones through...	Joel Rosart jrosart295	Aug 31, 2006 11:16 am
Yes, i witnessed exactly that - once they stopped taking it it kinda seemed like they were worse off than if they never did at all. No shortcuts in this life...	jason yana javidyana	Aug 31, 2006 3:14 am

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