Freeda,

My mom's repeat test came back worse. Here blast %age
is up to 26%. Her doctor has classified it as blast
stage. I thought blast stage was more than 30% blast
cells. But it seems WHO has a diff classification.

Here's what the doctor has proposed. (1) Increase
Gleevec dose from 300 to 600mg. (2) BMA in 2 weeks (3)
low cytometry for acute leukemia panel.

Her blast cells were checked in october 2005 and then
in feb 2006. The %age went up from 8 to 26%. So yes,
it was a dramatic increase. She was put on 400mg when
she started Gleevec initially. But her TLC would drop
so low that her therapy had to be stopped every 4
weeks for 2 weeks. So the docs put her on 300mg. Just
hoping her BMA results are not too bad.

Thanks & regards

Madhulika




--- Gleevec@yahoogroups.com wrote:

> There are 2 messages in this issue.
>
> Topics in this digest:
>
> 1. Re: Re: Chronic to Accelerated phase
> From: Silvia Keidel <sk6898@...>
> 2. Re: Digest Number 1147
> From: Freeda <no1freeda@...>
>
>
>
________________________________________________________________________
>
________________________________________________________________________
>
> Message: 1
> Date: Wed, 8 Feb 2006 12:10:47 -0800 (PST)
> From: Silvia Keidel <sk6898@...>
> Subject: Re: Re: Chronic to Accelerated phase
>
> Tracey:
> indeed you have confused me. But maybe I did not
> explain things in a very understandable way since
> english is my second language. I apologize.
> I agree with you on your last post. I hope that I
> will stay in chronic phase with treatment. Things
> are going good so far for me and my onc says that
> from all his patients I am the one with the best
> results so far. Of course I don't know what is
> laying ahead of me, but I hope for the best.
> Thanks again for your information!
>
> Best wishes,
> Silvia
>
>
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>
________________________________________________________________________
>
________________________________________________________________________
>
> Message: 2
> Date: Wed, 8 Feb 2006 16:26:49 -0800 (PST)
> From: Freeda <no1freeda@...>
> Subject: Re: Digest Number 1147
>
> Madhulika,
> I do hope there is help out there!! Did this come
> on suddenly after taking Gleevec? And I wonder why
> she wasn't given higher dosage right away??
> The best of everything to you and your mother!
> Freeda
>
>
>
>
> Dear Tracey,
>
> Thanks a lot. I spoke to Anjana. There are trials in
> Singapore. But my mum won't be eligible since the
> they
> are looking at patients who are resistant to min
> 400mg
> of Gleevec. My mum's been taking 300 mg. Her repeat
> test results came back even worse. The blast cells
> are
> at 26%. Her doc appointment is today. They are
> considering higher dosage of Gleevec or even
> combination therapy. We will know exactly by
> evening.
> Keeping my fingers crossed.
>
> Thanks and regards
>
> Madhulika
>
>
> Freeda
>
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