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Chronic to Accelerated phase   Message List  
Reply | Forward Message #4783 of 4801 |
Re: Chronic to Accelerated phase

Hi Silvia,

I'm not sure what you're talking about. I don't recall saying that
we couldn't stay in one phase with treatment. The goal is exactly
that, to halt the progression of the disease and this can only be
done with treatment.

Ideally, we want to remain in some form of remission where the
disease is fully controlled. If this cannot be achieved, the next
best thing would be to remain in the chronic phase which is not
fatal.

The problem is that CML can sometimes be unpredictable and we could
potentially advance to the accelerated phase despite treatment.
Thankfully however, this is not common. Although uncommon, it is
still possible so that's why we're so lucky to have these second
generation drugs coming through the pipe line. These drugs are
showing great promise for patients who have stopped responding to
Gleevec.

I'm not in the medical field but I have spent the last four years
since my diagnosis, reading medical journals and educating myself on
this disease.

I hope I haven't confused you.
Tracey







Sat Feb 4, 2006 3:41 am

traceyincanada
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Message #4783 of 4801 |
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Hi All, Its good to see some activity on the group. I have a question for you all. My mum's been CML patient for last 9 years. Started Gleevec nearly 4 years...
madhumathur
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Feb 2, 2006
2:13 am

Hi Madhulika, I'm sorry to hear about your mother. Why is she not in one of the trials for Gleevec resistant patients? There are two very promising new drugs...
Tracey
traceyincanada
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Feb 2, 2006
3:22 am

I hope I am right, but according to my onc, one does not switch phases once it is determined what kind of leukemia one has. If she has been on Gleevec for so...
Silvia Keidel
sk6898
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Feb 2, 2006
3:24 am

... phases once it is determined what kind of leukemia one has. If she has been on Gleevec for so long, and it is working, she must be in remission. Is...
Tracey
traceyincanada
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Feb 2, 2006
3:39 am

Tracey: thank you for your reply, I am sorry to be wrong, but how do you know this? I am very confused now, since my onc told me that one does not switch...
Silvia Keidel
sk6898
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Feb 2, 2006
3:58 am

Hi Silvia, Well I know this because I've seen many patients return to chronic phase after being in the accelerated phase or even blast phase. This is the goal...
Tracey
traceyincanada
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Feb 2, 2006
3:00 pm

Tracey, thank you very much for your information. Are you in the medical field? As far as the phases go, I always believed that without treatment a patient...
Silvia Keidel
sk6898
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Feb 3, 2006
6:25 pm

Hi Silvia, I'm not sure what you're talking about. I don't recall saying that we couldn't stay in one phase with treatment. The goal is exactly that, to halt...
Tracey
traceyincanada
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Feb 4, 2006
3:42 am

Tracey: indeed you have confused me. But maybe I did not explain things in a very understandable way since english is my second language. I apologize. I...
Silvia Keidel
sk6898
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Feb 8, 2006
8:12 pm

... phases once it is determined what kind of leukemia one has. If she has been on Gleevec for so long, and it is working, she must be in remission. Is...
telephonics
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Feb 11, 2006
9:49 pm

@telephonics: yes, I think I might have been mistaken, and thanks to Tracey's info I got to think about it some more. However, I will see my onc next week...
Silvia Keidel
sk6898
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Feb 12, 2006
4:36 am
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